STRINGSTRING
PTPN11 PTPN11 GFAP GFAP AGER AGER EIF2B5 EIF2B5 LOC102745161 LOC102745161 LOC102741358 LOC102741358 SOX8 SOX8 LOC102747093 LOC102747093 GPR37L1 GPR37L1 IFNG IFNG MAPK1 MAPK1 DLL1 DLL1 LOC102727345 LOC102727345 S100A9 S100A9 ABL1 ABL1 LOC102738254 LOC102738254 NF1 NF1 LAMB2 LAMB2 S100B S100B BMP2 BMP2 STAT3 STAT3 LOC102749048 LOC102749048 KRAS KRAS LOC102732823 LOC102732823 CNTF CNTF LOC102729094 LOC102729094 PAX6 PAX6 TREM2 TREM2 LOC102741936 LOC102741936 NR2E1 NR2E1 LOC102731565 LOC102731565
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
GFAPGlial fibrillary acidic protein isoform X1; Belongs to the intermediate filament family. (432 aa)
AGERAdvanced glycosylation end product-specific receptor. (397 aa)
EIF2B5Translation initiation factor eIF-2B subunit epsilon. (718 aa)
LOC102745161Signal transducer and activator of transcription 3-like. (301 aa)
LOC102741358Protein S100; Belongs to the S-100 family. (89 aa)
SOX8Transcription factor SOX-8. (412 aa)
LOC102747093Tetraspanin-2-like; Belongs to the tetraspanin (TM4SF) family. (115 aa)
GPR37L1Prosaposin receptor GPR37L1. (477 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (326 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (724 aa)
LOC102727345Transcription factor SOX-9-like. (282 aa)
S100A9Protein S100; Belongs to the S-100 family. (140 aa)
ABL1Tyrosine-protein kinase ABL1-like. (312 aa)
LOC102738254Vimentin-like; Belongs to the intermediate filament family. (209 aa)
NF1Neurofibromin-like. (1269 aa)
LAMB2Laminin subunit beta-2 isoform X1. (1801 aa)
S100BProtein S100; Belongs to the S-100 family. (92 aa)
BMP2Bone morphogenetic protein 2-like. (395 aa)
STAT3Signal transducer and activator of transcription 3-like. (424 aa)
LOC102749048Myelin proteolipid protein-like isoform X1. (277 aa)
KRASGTPase KRas isoform X2. (188 aa)
LOC102732823Vimentin-like isoform X1; Belongs to the intermediate filament family. (466 aa)
CNTFCiliary neurotrophic factor. (199 aa)
LOC102729094Tetraspanin-2-like; Belongs to the tetraspanin (TM4SF) family. (106 aa)
PAX6Paired box protein Pax-6. (221 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (261 aa)
LOC102741936Trem-like transcript 1 protein-like. (128 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (385 aa)
LOC102731565Laminin subunit gamma-3-like. (231 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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