STRINGSTRING
LOC102729094 LOC102729094 EIF2B3 EIF2B3 PAX6 PAX6 MYRF MYRF VTN VTN DLX1 DLX1 PTEN PTEN NKX2-2 NKX2-2 TRPC4 TRPC4 MTOR MTOR CNTN2 CNTN2 PRDM8 PRDM8 MED12 MED12 NKX6-1 NKX6-1 EIF2B5 EIF2B5 ERCC2 ERCC2 SOX8 SOX8 LOC102747093 LOC102747093 NTRK2 NTRK2 LOC102741496 LOC102741496 LOC102736999 LOC102736999 DLX2 DLX2 CNTN1 CNTN1 NKX2-1 NKX2-1 WASF3 WASF3 KCNJ10 KCNJ10 NKX6-2 NKX6-2 CNP CNP FA2H FA2H TPPP TPPP LOC102727345 LOC102727345 EIF2B2 EIF2B2 TENM4 TENM4 SOX10 SOX10 LOC102732425 LOC102732425 NF1 NF1 EIF2B4 EIF2B4 NCSTN NCSTN LOC102749048 LOC102749048 CDK5 CDK5 LOC102744935 LOC102744935 LOC102729428 LOC102729428 LOC102734263 LOC102734263
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC102729094Tetraspanin-2-like; Belongs to the tetraspanin (TM4SF) family. (106 aa)
EIF2B3Translation initiation factor eIF-2B subunit gamma. (451 aa)
PAX6Paired box protein Pax-6. (221 aa)
MYRFMyelin regulatory factor. (604 aa)
VTNVitronectin. (456 aa)
DLX1Homeobox protein DLX-1 isoform X1. (255 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
NKX2-2Homeobox protein Nkx-2.2. (273 aa)
TRPC4Short transient receptor potential channel 4 isoform X1; Belongs to the transient receptor (TC 1.A.4) family. (982 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2550 aa)
CNTN2Contactin-2. (903 aa)
PRDM8PR domain zinc finger protein 8. (470 aa)
MED12Mediator of RNA polymerase II transcription subunit 12. (812 aa)
NKX6-1Homeobox protein Nkx-6.1-like. (366 aa)
EIF2B5Translation initiation factor eIF-2B subunit epsilon. (718 aa)
ERCC2TFIIH basal transcription factor complex helicase XPD subunit. (661 aa)
SOX8Transcription factor SOX-8. (412 aa)
LOC102747093Tetraspanin-2-like; Belongs to the tetraspanin (TM4SF) family. (115 aa)
NTRK2BDNF/NT-3 growth factors receptor-like. (420 aa)
LOC102741496BDNF/NT-3 growth factors receptor-like. (97 aa)
LOC102736999Dual specificity protein phosphatase 10-like; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (177 aa)
DLX2Homeobox protein DLX-2. (330 aa)
CNTN1Contactin-1-like isoform X1. (1018 aa)
NKX2-1Homeobox protein Nkx-2.1. (252 aa)
WASF3wiskott-Aldrich syndrome protein family member 3-like. (328 aa)
KCNJ10ATP-sensitive inward rectifier potassium channel 10. (379 aa)
NKX6-2Homeobox protein Nkx-6.2. (168 aa)
CNP2',3'-cyclic-nucleotide 3'-phosphodiesterase; May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin; Belongs to the 2H phosphoesterase superfamily. CNPase family. (420 aa)
FA2HFatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] (372 aa)
TPPPTubulin polymerization-promoting protein. (221 aa)
LOC102727345Transcription factor SOX-9-like. (282 aa)
EIF2B2Translation initiation factor eIF-2B subunit beta; Belongs to the eIF-2B alpha/beta/delta subunits family. (351 aa)
TENM4Teneurin-4. (1083 aa)
SOX10Transcription factor SOX-10. (469 aa)
LOC102732425Myelin-associated glycoprotein-like. (382 aa)
NF1Neurofibromin-like. (1269 aa)
EIF2B4Translation initiation factor eIF-2B subunit delta isoform X1; Belongs to the eIF-2B alpha/beta/delta subunits family. (544 aa)
NCSTNNicastrin. (602 aa)
LOC102749048Myelin proteolipid protein-like isoform X1. (277 aa)
CDK5Cyclin-dependent kinase 5 isoform X1; Belongs to the protein kinase superfamily. (292 aa)
LOC102744935Translation initiation factor eIF-2B subunit alpha-like; Belongs to the eIF-2B alpha/beta/delta subunits family. (75 aa)
LOC102729428Translation initiation factor eIF-2B subunit alpha-like; Belongs to the eIF-2B alpha/beta/delta subunits family. (114 aa)
LOC102734263Translation initiation factor eIF-2B subunit alpha-like; Belongs to the eIF-2B alpha/beta/delta subunits family. (142 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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