(17 nodes) Neural nucleus development network (Leptonychotes weddellii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ATF2	Cyclic AMP-dependent transcription factor ATF-2 isoform X2. (505 aa)
	NKX2-1	Homeobox protein Nkx-2.1. (252 aa)
	PHOX2B	Paired mesoderm homeobox protein 2B. (285 aa)
	HOXB2	Homeobox protein Hox-B2. (349 aa)
	HOXB1	Homeobox protein Hox-B1. (304 aa)
	NKX2-2	Homeobox protein Nkx-2.2. (273 aa)
	SEC24B	Protein transport protein Sec24B isoform X1. (1258 aa)
	LRRC1	Leucine-rich repeat-containing protein 1. (242 aa)
	ARX	Homeobox protein ARX. (457 aa)
	LOC102726777	Cyclin-dependent kinase 5 activator 2-like. (98 aa)
	LOC102742272	Aldehyde dehydrogenase family 1 member A3-like. (127 aa)
	FGF2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (113 aa)
	LOC102745732	Leucine-rich repeat-containing protein 1-like. (92 aa)
	LOC102749599	Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (420 aa)
	KCNE1	Potassium voltage-gated channel subfamily E member 1 isoform X2. (124 aa)
	ALDH1A3	Aldehyde dehydrogenase family 1 member A3; Belongs to the aldehyde dehydrogenase family. (261 aa)
	KIRREL3	Kin of IRRE-like protein 3. (745 aa)

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALDH1A3	LOC102742272	A0A2U3YD02	A0A2U3Z6U1	Aldehyde dehydrogenase family 1 member A3; Belongs to the aldehyde dehydrogenase family.	Aldehyde dehydrogenase family 1 member A3-like.	0.951
HOXB1	HOXB2	A0A2U3Y5X5	A0A2U3Y668	Homeobox protein Hox-B1.	Homeobox protein Hox-B2.	0.484
HOXB2	HOXB1	A0A2U3Y668	A0A2U3Y5X5	Homeobox protein Hox-B2.	Homeobox protein Hox-B1.	0.484
LOC102742272	ALDH1A3	A0A2U3Z6U1	A0A2U3YD02	Aldehyde dehydrogenase family 1 member A3-like.	Aldehyde dehydrogenase family 1 member A3; Belongs to the aldehyde dehydrogenase family.	0.951
LOC102745732	LRRC1	A0A2U3YZQ7	A0A2U3X9T6	Leucine-rich repeat-containing protein 1-like.	Leucine-rich repeat-containing protein 1.	0.900
LRRC1	LOC102745732	A0A2U3X9T6	A0A2U3YZQ7	Leucine-rich repeat-containing protein 1.	Leucine-rich repeat-containing protein 1-like.	0.900