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LOC102747944 LOC102747944 NDUFAF2 NDUFAF2 NR1H3 NR1H3 OPRM1 OPRM1 HMGCR HMGCR F2R F2R PTPN11 PTPN11 ADRA2A ADRA2A INHBB INHBB ADTRP ADTRP GHRL GHRL ACVR1C ACVR1C MIDN MIDN RAB11FIP1 RAB11FIP1 RSAD2 RSAD2 FKBP1B FKBP1B SIRT4 SIRT4 SFRP1 SFRP1 DRD3 DRD3 PFKL PFKL KLF7 KLF7 KCNJ11 KCNJ11 INS INS FOXO1 FOXO1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC102747944Potassium voltage-gated channel subfamily B member 1-like. (189 aa)
NDUFAF2Mimitin, mitochondrial. (169 aa)
NR1H3Oxysterols receptor LXR-alpha isoform X1. (456 aa)
OPRM1Mu-type opioid receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (403 aa)
HMGCR3-hydroxy-3-methylglutaryl coenzyme A reductase. (887 aa)
F2RProteinase-activated receptor 1; Belongs to the G-protein coupled receptor 1 family. (427 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
ADRA2Aalpha-2A adrenergic receptor. (350 aa)
INHBBInhibin beta B chain. (320 aa)
ADTRPAndrogen-dependent TFPI-regulating protein. (260 aa)
GHRLAppetite-regulating hormone isoform X1. (117 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (443 aa)
MIDNMidnolin. (489 aa)
RAB11FIP1Rab11 family-interacting protein 1 isoform X1. (1274 aa)
RSAD2Radical S-adenosyl methionine domain-containing protein 2. (245 aa)
FKBP1BPeptidylprolyl isomerase. (108 aa)
SIRT4NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] (314 aa)
SFRP1Secreted frizzled-related protein 1. (303 aa)
DRD3D(3) dopamine receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (400 aa)
PFKLATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (751 aa)
KLF7Krueppel-like factor 7-like isoform X1. (302 aa)
KCNJ11ATP-sensitive inward rectifier potassium channel 11. (390 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
FOXO1Forkhead box protein O1-like. (418 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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