STRINGSTRING
ACO1 ACO1 VDR VDR PLS1 PLS1 UGCG UGCG NPC1 NPC1 KCNQ1 KCNQ1 NPC1L1 NPC1L1 FABP2 FABP2 VILL VILL CEL CEL LDLR LDLR F11R F11R LEP LEP VIL1 VIL1 LOC102732141 LOC102732141 LOC102738856 LOC102738856 LOC102741867 LOC102741867
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACO1Cytoplasmic aconitate hydratase; Belongs to the aconitase/IPM isomerase family. (889 aa)
VDRVitamin D3 receptor. (427 aa)
PLS1Plastin-1. (604 aa)
UGCGCeramide glucosyltransferase. (275 aa)
NPC1niemann-Pick C1 protein. (1276 aa)
KCNQ1Potassium voltage-gated channel subfamily KQT member 1; Belongs to the potassium channel family. (599 aa)
NPC1L1niemann-Pick C1-like protein 1. (1331 aa)
FABP2Fatty acid-binding protein, intestinal; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
VILLVillin-like protein-like. (375 aa)
CELCarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (607 aa)
LDLRLow-density lipoprotein receptor. (861 aa)
F11RJunctional adhesion molecule A. (298 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (166 aa)
VIL1Villin-1. (330 aa)
LOC102732141Iron-responsive element-binding protein 2-like. (229 aa)
LOC102738856Villin-like protein-like. (205 aa)
LOC102741867Villin-1-like. (505 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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