(30 nodes) Regulation of lipid catabolic process network (Leptonychotes weddellii)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

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protein homology

Your Input:
	ABHD5	1-acylglycerol-3-phosphate O-acyltransferase ABHD5. (349 aa)
	ABCD1	ATP-binding cassette sub-family D member 1. (825 aa)
	AKT3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (418 aa)
	LRRN4CL	LRRN4 C-terminal-like protein. (237 aa)
	BSCL2	Seipin isoform X2. (394 aa)
	METTL20	Methyltransferase-like protein 20. (266 aa)
	ABCD2	ATP-binding cassette sub-family D member 2 isoform X2. (742 aa)
	ADRA2A	alpha-2A adrenergic receptor. (350 aa)
	LOC102733378	UPF0562 protein C7orf55 homolog. (113 aa)
	LTK	LOW QUALITY PROTEIN: leukocyte tyrosine kinase receptor. (841 aa)
	RARRES2	Retinoic acid receptor responder protein 2 isoform X1. (163 aa)
	PRKAA1	Non-specific serine/threonine protein kinase. (559 aa)
	LONP2	Lon protease homolog 2, peroxisomal. (660 aa)
	GPLD1	Phosphatidylinositol-glycan-specific phospholipase D. (840 aa)
	LOC102737090	Sortilin-related receptor-like. (446 aa)
	IDH1	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa)
	AKT1	Non-specific serine/threonine protein kinase. (518 aa)
	AADAC	Arylacetamide deacetylase. (399 aa)
	MFSD2A	Major facilitator superfamily domain-containing protein 2A isoform X1. (529 aa)
	TNF	Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
	PDE3B	Phosphodiesterase. (1180 aa)
	PNPLA2	Patatin-like phospholipase domain-containing protein 2. (486 aa)
	HCAR1	LOW QUALITY PROTEIN: hydroxycarboxylic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (360 aa)
	INS	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
	LOC102746352	Lon protease homolog 2, peroxisomal-like; Belongs to the peptidase S16 family. (206 aa)
	TYSND1	Peroxisomal leader peptide-processing protease. (356 aa)
	LOC102734938	Secretin-like. (108 aa)
	DAGLB	Sn1-specific diacylglycerol lipase beta. (671 aa)
	LGALS12	Galectin. (314 aa)
	LDLR	Low-density lipoprotein receptor. (861 aa)

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCD1	HCAR1	A0A2U3Y9Y2	A0A2U3Z949	ATP-binding cassette sub-family D member 1.	LOW QUALITY PROTEIN: hydroxycarboxylic acid receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.509
ABCD1	LGALS12	A0A2U3Y9Y2	A0A2U3YPP5	ATP-binding cassette sub-family D member 1.	Galectin.	0.495
ABCD2	HCAR1	A0A2U3X8E7	A0A2U3Z949	ATP-binding cassette sub-family D member 2 isoform X2.	LOW QUALITY PROTEIN: hydroxycarboxylic acid receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.509
ABCD2	LGALS12	A0A2U3X8E7	A0A2U3YPP5	ATP-binding cassette sub-family D member 2 isoform X2.	Galectin.	0.495
ABHD5	PNPLA2	A0A2U3YAA9	A0A2U3YCF5	1-acylglycerol-3-phosphate O-acyltransferase ABHD5.	Patatin-like phospholipase domain-containing protein 2.	0.963
AKT1	AKT3	A0A2U3Y3V3	A0A2U3Y8K7	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.808
AKT1	INS	A0A2U3Y3V3	A0A2U3Z329	Non-specific serine/threonine protein kinase.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.499
AKT1	PDE3B	A0A2U3Y3V3	A0A2U3YI06	Non-specific serine/threonine protein kinase.	Phosphodiesterase.	0.824
AKT1	PRKAA1	A0A2U3Y3V3	A0A2U3XPK0	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase.	0.453
AKT3	AKT1	A0A2U3Y8K7	A0A2U3Y3V3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase.	0.808
AKT3	INS	A0A2U3Y8K7	A0A2U3Z329	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.499
AKT3	PDE3B	A0A2U3Y8K7	A0A2U3YI06	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphodiesterase.	0.899
AKT3	PRKAA1	A0A2U3Y8K7	A0A2U3XPK0	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase.	0.454
BSCL2	PNPLA2	A0A2U3XGF4	A0A2U3YCF5	Seipin isoform X2.	Patatin-like phospholipase domain-containing protein 2.	0.482
HCAR1	ABCD1	A0A2U3Z949	A0A2U3Y9Y2	LOW QUALITY PROTEIN: hydroxycarboxylic acid receptor 1; Belongs to the G-protein coupled receptor 1 family.	ATP-binding cassette sub-family D member 1.	0.509
HCAR1	ABCD2	A0A2U3Z949	A0A2U3X8E7	LOW QUALITY PROTEIN: hydroxycarboxylic acid receptor 1; Belongs to the G-protein coupled receptor 1 family.	ATP-binding cassette sub-family D member 2 isoform X2.	0.509
HCAR1	LGALS12	A0A2U3Z949	A0A2U3YPP5	LOW QUALITY PROTEIN: hydroxycarboxylic acid receptor 1; Belongs to the G-protein coupled receptor 1 family.	Galectin.	0.620
INS	AKT1	A0A2U3Z329	A0A2U3Y3V3	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Non-specific serine/threonine protein kinase.	0.499
INS	AKT3	A0A2U3Z329	A0A2U3Y8K7	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.499
INS	LOC102734938	A0A2U3Z329	A0A2U3Z0B3	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Secretin-like.	0.487