(21 nodes) Negative regulation of lipid biosynthetic process network (Leptonychotes weddellii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ORMDL1	ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa)
	SNAI2	Zinc finger protein SNAI2. (268 aa)
	BMP5	Bone morphogenetic protein 5 isoform X2. (454 aa)
	ORMDL2	ORM1-like protein; Negative regulator of sphingolipid synthesis. (182 aa)
	SNAI1	Zinc finger protein SNAI1. (264 aa)
	NR0B1	Nuclear receptor subfamily 0 group B member 1. (393 aa)
	PRMT3	Protein arginine N-methyltransferase 3 isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (529 aa)
	ACADVL	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial isoform X1. (655 aa)
	LOC102746290	25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial-like; Belongs to the cytochrome P450 family. (508 aa)
	PIBF1	Progesterone-induced-blocking factor 1. (757 aa)
	SERPINA12	Serpin A12; Belongs to the serpin family. (416 aa)
	LOC102747801	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (219 aa)
	LOC102737823	Fibroblast growth factor 19-like; Belongs to the heparin-binding growth factors family. (115 aa)
	PDGFB	Platelet-derived growth factor subunit B isoform X1; Belongs to the PDGF/VEGF growth factor family. (241 aa)
	LPCAT1	Lysophosphatidylcholine acyltransferase 1. (447 aa)
	DKK3	Dickkopf-related protein 3. (286 aa)
	GPER1	G-protein coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (370 aa)
	DKKL1	Dickkopf-like protein 1 isoform X3. (237 aa)
	LOC102739775	Breast cancer type 1 susceptibility protein homolog. (471 aa)
	BMP2	Bone morphogenetic protein 2-like. (395 aa)
	LOC102750518	Tribbles homolog 3-like. (215 aa)

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP2	BMP5	A0A2U3Z3S1	A0A2U3XA39	Bone morphogenetic protein 2-like.	Bone morphogenetic protein 5 isoform X2.	0.497
BMP2	LOC102737823	A0A2U3Z3S1	A0A2U3YNM9	Bone morphogenetic protein 2-like.	Fibroblast growth factor 19-like; Belongs to the heparin-binding growth factors family.	0.475
BMP2	LOC102747801	A0A2U3Z3S1	A0A2U3YLJ1	Bone morphogenetic protein 2-like.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.534
BMP5	BMP2	A0A2U3XA39	A0A2U3Z3S1	Bone morphogenetic protein 5 isoform X2.	Bone morphogenetic protein 2-like.	0.497
LOC102737823	BMP2	A0A2U3YNM9	A0A2U3Z3S1	Fibroblast growth factor 19-like; Belongs to the heparin-binding growth factors family.	Bone morphogenetic protein 2-like.	0.475
LOC102747801	BMP2	A0A2U3YLJ1	A0A2U3Z3S1	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Bone morphogenetic protein 2-like.	0.534
SNAI1	SNAI2	A0A2U3XKB2	A0A2U3X8E1	Zinc finger protein SNAI1.	Zinc finger protein SNAI2.	0.455
SNAI2	SNAI1	A0A2U3X8E1	A0A2U3XKB2	Zinc finger protein SNAI2.	Zinc finger protein SNAI1.	0.455