STRINGSTRING
SLC39A14 SLC39A14 NOV NOV GDF5 GDF5 EPYC EPYC FGF18 FGF18 FGF4 FGF4 LOC102727345 LOC102727345 SERPINH1 SERPINH1 MEF2C MEF2C SULF2 SULF2 LOC102749599 LOC102749599 CER1 CER1 HAND1 HAND1 SMAD1 SMAD1 MSX1 MSX1 BMP7 BMP7 OGN OGN TWSG1 TWSG1 TRPV4 TRPV4 IFT80 IFT80 ATF2 ATF2 RARG RARG MMP13 MMP13 LECT1 LECT1 TAPT1 TAPT1 LOC102737096 LOC102737096 RB1 RB1 BGN BGN DLX2 DLX2 BMPR1A BMPR1A CYTL1 CYTL1 LTBP3 LTBP3 CTGF CTGF LOC102741200 LOC102741200 HOXD3 HOXD3 GPLD1 GPLD1 HOXB3 HOXB3 SATB2 SATB2 HIF1A HIF1A ZMPSTE24 ZMPSTE24 BMP3 BMP3 PTH1R PTH1R SRF SRF RARB RARB OSR1 OSR1 ZBTB16 ZBTB16 MYF5 MYF5 OTOR OTOR THBS3 THBS3 MEX3C MEX3C BMPR2 BMPR2 CYR61 CYR61 NPPC NPPC SFRP2 SFRP2 LOC102734562 LOC102734562 WNT10B WNT10B LOC102733272 LOC102733272 LOC102735151 LOC102735151 LOC102727186 LOC102727186 CHRDL2 CHRDL2 RUNX3 RUNX3 HYAL3 HYAL3 BMP2 BMP2 PITX1 PITX1 FGF2 FGF2 FGF6 FGF6 LOC102727681 LOC102727681 ANXA6 ANXA6 BMPR1B BMPR1B CSGALNACT1 CSGALNACT1 SNX19 SNX19 HOXA3 HOXA3 HOXA5 HOXA5 DDRGK1 DDRGK1 SNAI1 SNAI1 SULF1 SULF1 HOXA11 HOXA11 HMGA2 HMGA2 OSR2 OSR2 SMPD3 SMPD3 NOG NOG COL2A1 COL2A1 HOXC4 HOXC4 ECM1 ECM1 FGF9 FGF9 WNT2B WNT2B LOC102740547 LOC102740547 BBS2 BBS2 CBS CBS IL17F IL17F COMP COMP BBS1 BBS1 TGFB1 TGFB1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SLC39A14Zinc transporter ZIP14 isoform X1. (490 aa)
NOVProtein NOV homolog. (353 aa)
GDF5Growth/differentiation factor 5. (499 aa)
EPYCEpiphycan. (321 aa)
FGF18Fibroblast growth factor 18. (116 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (172 aa)
LOC102727345Transcription factor SOX-9-like. (282 aa)
SERPINH1Serpin H1 isoform X3; Belongs to the serpin family. (418 aa)
MEF2CMyocyte-specific enhancer factor 2C-like isoform X2. (473 aa)
SULF2N-acetylglucosamine-6-sulfatase. (412 aa)
LOC102749599Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (420 aa)
CER1Cerberus. (274 aa)
HAND1Heart- and neural crest derivatives-expressed protein 1. (218 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
MSX1Homeobox protein MSX-1. (303 aa)
BMP7Bone morphogenetic protein 7-like. (312 aa)
OGNMimecan. (208 aa)
TWSG1Twisted gastrulation protein homolog 1. (223 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (742 aa)
IFT80Intraflagellar transport protein 80 homolog. (777 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2 isoform X2. (505 aa)
RARGRetinoic acid receptor gamma isoform X1. (486 aa)
MMP13Collagenase 3. (470 aa)
LECT1Leukocyte cell-derived chemotaxin 1. (360 aa)
TAPT1Transmembrane anterior posterior transformation protein 1. (462 aa)
LOC102737096Retinoic acid receptor beta-like. (262 aa)
RB1Retinoblastoma-associated protein. (846 aa)
BGNBiglycan; May be involved in collagen fiber assembly. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. (369 aa)
DLX2Homeobox protein DLX-2. (330 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
CYTL1Cytokine-like protein 1. (133 aa)
LTBP3Latent-transforming growth factor beta-binding protein 3-like. (1159 aa)
CTGFConnective tissue growth factor. (211 aa)
LOC102741200Exostosin-1-like; Belongs to the glycosyltransferase 47 family. (746 aa)
HOXD3Homeobox protein Hox-D3. (432 aa)
GPLD1Phosphatidylinositol-glycan-specific phospholipase D. (840 aa)
HOXB3Homeobox protein Hox-B3. (211 aa)
SATB2DNA-binding protein SATB. (342 aa)
HIF1AHypoxia-inducible factor 1-alpha isoform X1. (823 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
BMP3Bone morphogenetic protein 3; Belongs to the TGF-beta family. (475 aa)
PTH1RLOW QUALITY PROTEIN: parathyroid hormone/parathyroid hormone-related peptide receptor; Belongs to the G-protein coupled receptor 2 family. (608 aa)
SRFSerum response factor. (508 aa)
RARBRetinoic acid receptor beta. (172 aa)
OSR1Protein odd-skipped-related 1 isoform X1. (267 aa)
ZBTB16Zinc finger and BTB domain-containing protein 16 isoform X1. (673 aa)
MYF5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
OTORLOW QUALITY PROTEIN: otoraplin. (129 aa)
THBS3Thrombospondin-3 isoform X1. (956 aa)
MEX3CRNA-binding E3 ubiquitin-protein ligase MEX3C. (465 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (974 aa)
CYR61Protein CYR61. (382 aa)
NPPCC-type natriuretic peptide isoform X1. (126 aa)
SFRP2Secreted frizzled-related protein 2. (294 aa)
LOC102734562Inositol monophosphatase 3-like. (171 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
LOC102733272Cartilage matrix protein-like. (279 aa)
LOC102735151Bone morphogenetic protein 7-like. (139 aa)
LOC102727186Heart- and neural crest derivatives-expressed protein 2-like. (217 aa)
CHRDL2Chordin-like protein 2-like. (333 aa)
RUNX3Runt-related transcription factor 3-like. (283 aa)
HYAL3Hyaluronidase. (419 aa)
BMP2Bone morphogenetic protein 2-like. (395 aa)
PITX1Homeobox protein. (312 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (113 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (182 aa)
LOC102727681Exostosin-2-like. (142 aa)
ANXA6Annexin. (673 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
CSGALNACT1Hexosyltransferase. (530 aa)
SNX19Sorting nexin-19-like. (868 aa)
HOXA3Homeobox protein Hox-A3. (440 aa)
HOXA5Homeobox protein Hox-A5. (270 aa)
DDRGK1DDRGK domain-containing protein 1. (315 aa)
SNAI1Zinc finger protein SNAI1. (264 aa)
SULF1Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (867 aa)
HOXA11Homeobox protein Hox-A11. (321 aa)
HMGA2High mobility group protein HMGI-C. (109 aa)
OSR2Protein odd-skipped-related 2 isoform X1. (312 aa)
SMPD3Sphingomyelin phosphodiesterase 3 isoform X1. (653 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
COL2A1Collagen alpha-1(II) chain isoform X1. (1487 aa)
HOXC4Homeobox protein Hox-C4 isoform X2. (263 aa)
ECM1LOW QUALITY PROTEIN: extracellular matrix protein 1. (550 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (393 aa)
LOC102740547Bone morphogenetic protein 4-like isoform X1. (409 aa)
BBS2Bardet-Biedl syndrome 2 protein-like. (603 aa)
CBSCystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (572 aa)
IL17Finterleukin-17F. (157 aa)
COMPCartilage oligomeric matrix protein. (728 aa)
BBS1Bardet-Biedl syndrome 1 protein. (540 aa)
TGFB1Transforming growth factor beta-1. (261 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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