STRINGSTRING
KHDC3L KHDC3L LINGO4 LINGO4 LRRTM1 LRRTM1 KRAS KRAS NLGN1 NLGN1 SLITRK3 SLITRK3 UFL1 UFL1 LOC102745089 LOC102745089 LOC102726335 LOC102726335 SLITRK6 SLITRK6 LOC102736404 LOC102736404 SLITRK1 SLITRK1 FLRT3 FLRT3 MTOR MTOR PLXNA4 PLXNA4 LRRN1 LRRN1 CUX2 CUX2 GFAP GFAP PRKCI PRKCI SRF SRF LOC102728321 LOC102728321 LOC102730452 LOC102730452 LOC102745156 LOC102745156 KDM1A KDM1A NR2E1 NR2E1 ITGB1 ITGB1 EPHB2 EPHB2 NKX6-1 NKX6-1 EPHB3 EPHB3 ZFYVE27 ZFYVE27 LOC102745362 LOC102745362 TNF TNF HIF1A HIF1A SLITRK4 SLITRK4 GHRL GHRL PLXNA1 PLXNA1 AMIGO2 AMIGO2 SOX8 SOX8 NGF NGF LAYN LAYN NTRK2 NTRK2 LOC102741496 LOC102741496 MECP2 MECP2 PLXNA3 PLXNA3 PLAG1 PLAG1 NEURL1 NEURL1 VEGFC VEGFC LRRTM2 LRRTM2 IFNG IFNG LOC102746893 LOC102746893 SEMA7A SEMA7A SPEN SPEN ISLR ISLR ISLR2 ISLR2 LOC102735405 LOC102735405 POU4F2 POU4F2 LIG4 LIG4 PAFAH1B1 PAFAH1B1 TGM2 TGM2 LPHN2 LPHN2 DHX36 DHX36 LRTM2 LRTM2 IST1 IST1 SMARCD3 SMARCD3 ZNF365 ZNF365 WNT3A WNT3A CLCF1 CLCF1 WNT3 WNT3 SRPX2 SRPX2 OTP OTP KIAA1598 KIAA1598 NKX6-2 NKX6-2 LOC102738222 LOC102738222 GOLGA4 GOLGA4 LRRC24 LRRC24 PAX6 PAX6 LOC102751154 LOC102751154 XRCC2 XRCC2 RASSF10 RASSF10 LOC102739340 LOC102739340 TRIM32 TRIM32 TGFB1 TGFB1 BHLHB9 BHLHB9 TENM4 TENM4 IL34 IL34 LRRC4B LRRC4B SOX10 SOX10 LOC102732425 LOC102732425 NTN1 NTN1 MEGF8 MEGF8 NTRK1 NTRK1 GPER1 GPER1 CAPRIN1 CAPRIN1 CLSTN2 CLSTN2 LOC102731237 LOC102731237 FGF2 FGF2 LOC102746061 LOC102746061 BMP2 BMP2 NUMBL NUMBL LOC102746247 LOC102746247 LOC102746856 LOC102746856 LOC102738767 LOC102738767 SEMA4A SEMA4A LOC102734560 LOC102734560 LOC102727190 LOC102727190 NEFL NEFL LOC102747252 LOC102747252 CAPRIN2 CAPRIN2 LOC102728392 LOC102728392 CBLN1 CBLN1 NUMB NUMB CDKL3 CDKL3 JADE2 JADE2 NIN NIN LRRN2 LRRN2 DMRTA2 DMRTA2 IL1RAPL2 IL1RAPL2 VSTM5 VSTM5 PLXNB1 PLXNB1 DBN1 DBN1 MAP3K13 MAP3K13 GRID2 GRID2 SRRT SRRT LOC102748159 LOC102748159 OPRM1 OPRM1 BMPR2 BMPR2 EGR2 EGR2 FZD3 FZD3
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KHDC3LKHDC3-like protein. (235 aa)
LINGO4Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 4. (593 aa)
LRRTM1Leucine-rich repeat transmembrane neuronal protein 1-like. (522 aa)
KRASGTPase KRas isoform X2. (188 aa)
NLGN1Neuroligin-1-like. (619 aa)
SLITRK3SLIT and NTRK-like protein 3 isoform X1. (979 aa)
UFL1E3 UFM1-protein ligase 1. (792 aa)
LOC102745089annotation not available (606 aa)
LOC102726335Glutamate receptor ionotropic, delta-2-like isoform X1. (787 aa)
SLITRK6SLIT and NTRK-like protein 6. (840 aa)
LOC102736404SLIT and NTRK-like protein 5-like. (963 aa)
SLITRK1SLIT and NTRK-like protein 1. (696 aa)
FLRT3Leucine-rich repeat transmembrane protein FLRT3 isoform X1. (649 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2550 aa)
PLXNA4plexin-A4-like. (1473 aa)
LRRN1Leucine-rich repeat neuronal protein 1. (716 aa)
CUX2One cut domain family member. (510 aa)
GFAPGlial fibrillary acidic protein isoform X1; Belongs to the intermediate filament family. (432 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (543 aa)
SRFSerum response factor. (508 aa)
LOC102728321High affinity nerve growth factor receptor-like. (109 aa)
LOC102730452semaphorin-4A-like; Belongs to the semaphorin family. (436 aa)
LOC102745156Catenin beta-1-like isoform X1. (216 aa)
KDM1ALysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (876 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (385 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
EPHB2Ephrin type-B receptor 2-like isoform X1. (545 aa)
NKX6-1Homeobox protein Nkx-6.1-like. (366 aa)
EPHB3Ephrin type-B receptor 3. (883 aa)
ZFYVE27Protrudin. (411 aa)
LOC102745362Calsyntenin-3-like. (404 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
HIF1AHypoxia-inducible factor 1-alpha isoform X1. (823 aa)
SLITRK4SLIT and NTRK-like protein 4-like isoform X1. (838 aa)
GHRLAppetite-regulating hormone isoform X1. (117 aa)
PLXNA1plexin-A1. (1911 aa)
AMIGO2Amphoterin-induced protein 2. (521 aa)
SOX8Transcription factor SOX-8. (412 aa)
NGFBeta-nerve growth factor; Belongs to the NGF-beta family. (241 aa)
LAYNLayilin. (380 aa)
NTRK2BDNF/NT-3 growth factors receptor-like. (420 aa)
LOC102741496BDNF/NT-3 growth factors receptor-like. (97 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (499 aa)
PLXNA3plexin-A3. (1452 aa)
PLAG1Zinc finger protein PLAG1 isoform X1. (499 aa)
NEURL1Neuralized-like protein 1A. (574 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (419 aa)
LRRTM2Leucine-rich repeat transmembrane neuronal protein 2 isoform X1. (516 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa)
LOC102746893Synapse differentiation-inducing gene protein 1-like. (258 aa)
SEMA7Asemaphorin-7A isoform X1; Belongs to the semaphorin family. (663 aa)
SPENMsx2-interacting protein. (3050 aa)
ISLRImmunoglobulin superfamily containing leucine-rich repeat protein. (426 aa)
ISLR2Immunoglobulin superfamily containing leucine-rich repeat protein 2. (746 aa)
LOC102735405Chondrolectin-like. (141 aa)
POU4F2POU domain protein. (408 aa)
LIG4DNA ligase. (911 aa)
PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha. (148 aa)
TGM2Protein-glutamine gamma-glutamyltransferase 2-like. (548 aa)
LPHN2Latrophilin-2-like isoform X1; Belongs to the G-protein coupled receptor 2 family. (1403 aa)
DHX36Probable ATP-dependent RNA helicase DHX36 isoform X1. (1011 aa)
LRTM2Leucine-rich repeat and transmembrane domain-containing protein 2. (370 aa)
IST1IST1 homolog isoform X1. (364 aa)
SMARCD3SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3. (435 aa)
ZNF365Protein ZNF365. (407 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
CLCF1Cardiotrophin-like cytokine factor 1. (215 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (338 aa)
SRPX2Sushi repeat-containing protein SRPX2. (465 aa)
OTPHomeobox protein orthopedia. (325 aa)
KIAA1598Shootin-1 isoform X1. (631 aa)
NKX6-2Homeobox protein Nkx-6.2. (168 aa)
LOC102738222RING finger protein 112-like. (617 aa)
GOLGA4Golgin subfamily A member 4 isoform X1. (2250 aa)
LRRC24Leucine-rich repeat-containing protein 24. (514 aa)
PAX6Paired box protein Pax-6. (221 aa)
LOC102751154Numb-like protein-like. (141 aa)
XRCC2DNA repair protein XRCC2. (280 aa)
RASSF10Ras association domain-containing protein 10. (498 aa)
LOC102739340Oncomodulin-like; Belongs to the parvalbumin family. (109 aa)
TRIM32E3 ubiquitin-protein ligase TRIM32-like isoform X1. (655 aa)
TGFB1Transforming growth factor beta-1. (261 aa)
BHLHB9Protein BHLHb9. (550 aa)
TENM4Teneurin-4. (1083 aa)
IL34Interleukin-34. (236 aa)
LRRC4BLeucine-rich repeat-containing protein 4B. (646 aa)
SOX10Transcription factor SOX-10. (469 aa)
LOC102732425Myelin-associated glycoprotein-like. (382 aa)
NTN1Netrin-1-like. (402 aa)
MEGF8Multiple epidermal growth factor-like domains protein 8. (2068 aa)
NTRK1Tyrosine-protein kinase receptor. (592 aa)
GPER1G-protein coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (370 aa)
CAPRIN1Caprin-1. (709 aa)
CLSTN2Calsyntenin-2. (508 aa)
LOC102731237SNW domain-containing protein 1-like. (340 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (113 aa)
LOC102746061Homeobox protein cut-like 2-like. (698 aa)
BMP2Bone morphogenetic protein 2-like. (395 aa)
NUMBLNumb-like protein-like. (413 aa)
LOC102746247L-dopachrome tautomerase-like. (413 aa)
LOC102746856Platelet-activating factor acetylhydrolase IB subunit alpha-like isoform X1. (239 aa)
LOC102738767plexin-A4-like. (456 aa)
SEMA4Asemaphorin-4A-like. (350 aa)
LOC102734560plexin-A2-like. (296 aa)
LOC102727190Serine/threonine-protein kinase STK11-like. (545 aa)
NEFLNeurofilament light polypeptide; Belongs to the intermediate filament family. (545 aa)
LOC102747252Protein kinase C eta type-like. (89 aa)
CAPRIN2Caprin-2 isoform X1. (1068 aa)
LOC102728392ephrin-A5-like; Belongs to the ephrin family. (191 aa)
CBLN1Cerebellin-1. (193 aa)
NUMBProtein numb homolog isoform X1. (653 aa)
CDKL3Cyclin-dependent kinase-like 3 isoform X2. (590 aa)
JADE2Protein Jade-2 isoform X2. (784 aa)
NINNinein isoform X1. (2089 aa)
LRRN2Leucine-rich repeat neuronal protein 2. (720 aa)
DMRTA2Doublesex- and mab-3-related transcription factor A2. (540 aa)
IL1RAPL2X-linked interleukin-1 receptor accessory protein-like 2. (645 aa)
VSTM5V-set and transmembrane domain-containing protein 5. (200 aa)
PLXNB1plexin-B1. (2137 aa)
DBN1Drebrin isoform X2. (653 aa)
MAP3K13Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (966 aa)
GRID2Glutamate receptor ionotropic, delta-2. (211 aa)
SRRTSerrate RNA effector molecule homolog. (872 aa)
LOC102748159Leucine-rich repeat transmembrane protein FLRT2-like. (660 aa)
OPRM1Mu-type opioid receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (403 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (974 aa)
EGR2E3 SUMO-protein ligase EGR2 isoform X1. (469 aa)
FZD3Frizzled-3 isoform X2; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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