STRINGSTRING
HAND1 HAND1 NOG NOG CHD7 CHD7 TNNC1 TNNC1 SMAD4 SMAD4 LOC102726900 LOC102726900 MYL2 MYL2 NKX2-5 NKX2-5 BMPR1A BMPR1A DLL4 DLL4 FOXH1 FOXH1 LOC102729478 LOC102729478 MED1 MED1 LOC102741543 LOC102741543 LOC102745028 LOC102745028 LOC102730020 LOC102730020
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HAND1Heart- and neural crest derivatives-expressed protein 1. (218 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
CHD7chromodomain-helicase-DNA-binding protein 7. (2429 aa)
TNNC1Troponin C, slow skeletal and cardiac muscles. (161 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
LOC102726900Mothers against decapentaplegic homolog 7-like. (178 aa)
MYL2Myosin regulatory light chain 2, ventricular/cardiac muscle isoform isoform X1. (166 aa)
NKX2-5Homeobox protein Nkx-2.5. (323 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
FOXH1Forkhead box protein H1. (360 aa)
LOC102729478Endothelin-1 receptor-like; Belongs to the G-protein coupled receptor 1 family. (253 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1582 aa)
LOC102741543Zinc finger protein ZFPM2-like. (827 aa)
LOC102745028Endothelin-1 receptor-like. (178 aa)
LOC102730020Myosin-7-like. (703 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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