(12 nodes) Response to lipoprotein particle network (Leptonychotes weddellii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC102741936	Trem-like transcript 1 protein-like. (128 aa)
	SMPD3	Sphingomyelin phosphodiesterase 3 isoform X1. (653 aa)
	SREBF2	Sterol regulatory element-binding protein 2-like. (557 aa)
	CDH13	Cadherin-13-like. (512 aa)
	CD9	Tetraspanin. (226 aa)
	ITGB1	Integrin beta; Belongs to the integrin beta chain family. (798 aa)
	ADTRP	Androgen-dependent TFPI-regulating protein. (260 aa)
	LDLR	Low-density lipoprotein receptor. (861 aa)
	FCER1G	High affinity immunoglobulin epsilon receptor subunit gamma. (94 aa)
	SOCS5	Suppressor of cytokine signaling 5. (536 aa)
	MYD88	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa)
	TREM2	Triggering receptor expressed on myeloid cells 2. (261 aa)

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD9	ITGB1	A0A2U3XX36	A0A2U3Y1P5	Tetraspanin.	Integrin beta; Belongs to the integrin beta chain family.	0.828
CD9	LOC102741936	A0A2U3XX36	A0A2U3XCU2	Tetraspanin.	Trem-like transcript 1 protein-like.	0.462
CD9	TREM2	A0A2U3XX36	A0A2U3XCQ7	Tetraspanin.	Triggering receptor expressed on myeloid cells 2.	0.462
FCER1G	LOC102741936	A0A2U3YL68	A0A2U3XCU2	High affinity immunoglobulin epsilon receptor subunit gamma.	Trem-like transcript 1 protein-like.	0.614
FCER1G	TREM2	A0A2U3YL68	A0A2U3XCQ7	High affinity immunoglobulin epsilon receptor subunit gamma.	Triggering receptor expressed on myeloid cells 2.	0.614
ITGB1	CD9	A0A2U3Y1P5	A0A2U3XX36	Integrin beta; Belongs to the integrin beta chain family.	Tetraspanin.	0.828
LOC102741936	CD9	A0A2U3XCU2	A0A2U3XX36	Trem-like transcript 1 protein-like.	Tetraspanin.	0.462
LOC102741936	FCER1G	A0A2U3XCU2	A0A2U3YL68	Trem-like transcript 1 protein-like.	High affinity immunoglobulin epsilon receptor subunit gamma.	0.614
LOC102741936	TREM2	A0A2U3XCU2	A0A2U3XCQ7	Trem-like transcript 1 protein-like.	Triggering receptor expressed on myeloid cells 2.	0.742
TREM2	CD9	A0A2U3XCQ7	A0A2U3XX36	Triggering receptor expressed on myeloid cells 2.	Tetraspanin.	0.462
TREM2	FCER1G	A0A2U3XCQ7	A0A2U3YL68	Triggering receptor expressed on myeloid cells 2.	High affinity immunoglobulin epsilon receptor subunit gamma.	0.614
TREM2	LOC102741936	A0A2U3XCQ7	A0A2U3XCU2	Triggering receptor expressed on myeloid cells 2.	Trem-like transcript 1 protein-like.	0.742