STRINGSTRING
SALL1 SALL1 LOC102728864 LOC102728864 EN1 EN1 ALX3 ALX3 FGF4 FGF4 SLC39A3 SLC39A3 LOC102727345 LOC102727345 TBX4 TBX4 SP9 SP9 ALDH1A2 ALDH1A2 MSX1 MSX1 SLC39A1 SLC39A1 TMEM231 TMEM231 LOC102746004 LOC102746004 LOC102733500 LOC102733500 IFT80 IFT80 FLVCR1 FLVCR1 ZIC3 ZIC3 LOC102739114 LOC102739114 RARG RARG LOC102737096 LOC102737096 BMPR1A BMPR1A LOC102741200 LOC102741200 HOXD10 HOXD10 HOXD13 HOXD13 LOC102739902 LOC102739902 HOXD12 HOXD12 EVX2 EVX2 TBX3 TBX3 PIAS4 PIAS4 TMEM107 TMEM107 PTCH1 PTCH1 BAK1 BAK1 HNF1A HNF1A RDH10 RDH10 LOC102747185 LOC102747185 RARB RARB OSR1 OSR1 ZBTB16 ZBTB16 LOC102747957 LOC102747957 RAX RAX SMAD4 SMAD4 BMPR2 BMPR2 SMOC1 SMOC1 LOC102732270 LOC102732270 SALL4 SALL4 RPGRIP1L RPGRIP1L RSPO2 RSPO2 B9D1 B9D1 FOXN1 FOXN1 SULF1 SULF1 HOXA9 HOXA9 HOXA11 HOXA11 ZNF219 ZNF219 FGF8 FGF8 MEOX2 MEOX2 NIPBL NIPBL GREM1 GREM1 OSR2 OSR2 GJA5 GJA5 GNA12 GNA12 NOG NOG FGF10 FGF10 CHD7 CHD7 COL2A1 COL2A1 HOXC10 HOXC10 HOXC13 HOXC13 HOXC11 HOXC11 FGF9 FGF9 LOC102733521 LOC102733521 INTU INTU PITX2 PITX2 SFRP2 SFRP2 LEF1 LEF1 SLC7A11 SLC7A11 SEMA3C SEMA3C ATRX ATRX MKS1 MKS1 LOC102743151 LOC102743151 LOC102740547 LOC102740547 LOC102727981 LOC102727981 PITX1 PITX1 LOC102742062 LOC102742062 LOC102727186 LOC102727186 LOC102750229 LOC102750229 SHH SHH LOC102733867 LOC102733867 LOC102744116 LOC102744116 KREMEN2 KREMEN2 LOC102731463 LOC102731463 LOC102734560 LOC102734560 LOC102734562 LOC102734562 LOC102734830 LOC102734830 ALX4 ALX4 COMP COMP MEGF8 MEGF8 NOTCH2 NOTCH2 LOC102736120 LOC102736120 MED31 MED31 MED1 MED1 GDF5 GDF5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SALL1Sal-like protein 1-like. (1314 aa)
LOC102728864R-spondin-4-like. (103 aa)
EN1Homeobox protein engrailed-like. (305 aa)
ALX3Homeobox protein aristaless-like 3. (200 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (172 aa)
SLC39A3Zinc transporter ZIP3. (314 aa)
LOC102727345Transcription factor SOX-9-like. (282 aa)
TBX4T-box transcription factor TBX4. (413 aa)
SP9Transcription factor Sp9. (355 aa)
ALDH1A2Retinal dehydrogenase 2 isoform X1; Belongs to the aldehyde dehydrogenase family. (518 aa)
MSX1Homeobox protein MSX-1. (303 aa)
SLC39A1Zinc transporter ZIP1 isoform X1. (324 aa)
TMEM231Transmembrane protein 231. (316 aa)
LOC102746004Bcl-2-like protein 11-like isoform X2. (140 aa)
LOC102733500Double homeobox protein A-like. (178 aa)
IFT80Intraflagellar transport protein 80 homolog. (777 aa)
FLVCR1Feline leukemia virus subgroup C receptor-related protein 1. (556 aa)
ZIC3Zinc finger protein ZIC 3. (465 aa)
LOC102739114Intraflagellar transport protein 140 homolog. (375 aa)
RARGRetinoic acid receptor gamma isoform X1. (486 aa)
LOC102737096Retinoic acid receptor beta-like. (262 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
LOC102741200Exostosin-1-like; Belongs to the glycosyltransferase 47 family. (746 aa)
HOXD10Homeobox protein Hox-D10. (340 aa)
HOXD13Homeobox protein Hox-D13. (204 aa)
LOC102739902Uncharacterized protein C1orf172 homolog. (397 aa)
HOXD12Homeobox protein Hox-D12. (270 aa)
EVX2Homeobox even-skipped homolog protein 2. (397 aa)
TBX3T-box transcription factor TBX3. (675 aa)
PIAS4E3 SUMO-protein ligase PIAS4. (503 aa)
TMEM107Transmembrane protein 107 isoform X1. (140 aa)
PTCH1Protein patched homolog 1. (1301 aa)
BAK1Bcl-2 homologous antagonist/killer. (211 aa)
HNF1AHepatocyte nuclear factor 1-alpha. (631 aa)
RDH10Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
LOC102747185Homeobox protein DLX-5-like. (214 aa)
RARBRetinoic acid receptor beta. (172 aa)
OSR1Protein odd-skipped-related 1 isoform X1. (267 aa)
ZBTB16Zinc finger and BTB domain-containing protein 16 isoform X1. (673 aa)
LOC102747957Meckel syndrome type 1 protein-like. (318 aa)
RAXRetinal homeobox protein Rx. (243 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (974 aa)
SMOC1SPARC-related modular calcium-binding protein 1. (410 aa)
LOC102732270Double homeobox protein A-like. (179 aa)
SALL4Sal-like protein 4. (1052 aa)
RPGRIP1LProtein fantom isoform X2. (1244 aa)
RSPO2R-spondin-2 isoform X1. (243 aa)
B9D1B9 domain-containing protein 1. (204 aa)
FOXN1Forkhead box protein N1 isoform X1. (641 aa)
SULF1Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (867 aa)
HOXA9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (272 aa)
HOXA11Homeobox protein Hox-A11. (321 aa)
ZNF219Zinc finger protein 219 isoform X1. (718 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (140 aa)
MEOX2Homeobox protein MOX-2. (303 aa)
NIPBLNipped-B protein. (2803 aa)
GREM1Gremlin. (184 aa)
OSR2Protein odd-skipped-related 2 isoform X1. (312 aa)
GJA5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (358 aa)
GNA12Guanine nucleotide-binding protein subunit alpha-12 isoform X1. (305 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (218 aa)
CHD7chromodomain-helicase-DNA-binding protein 7. (2429 aa)
COL2A1Collagen alpha-1(II) chain isoform X1. (1487 aa)
HOXC10Homeobox protein Hox-C10. (342 aa)
HOXC13Homeobox protein Hox-C13. (92 aa)
HOXC11Homeobox protein Hox-C11. (304 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
LOC102733521R-spondin-4-like. (154 aa)
INTUProtein inturned. (943 aa)
PITX2Homeobox protein. (325 aa)
SFRP2Secreted frizzled-related protein 2. (294 aa)
LEF1Lymphoid enhancer-binding factor 1 isoform X1. (399 aa)
SLC7A11Cystine/glutamate transporter-like isoform X2. (503 aa)
SEMA3Csemaphorin-3C; Belongs to the semaphorin family. (696 aa)
ATRXTranscriptional regulator ATRX isoform X1. (2489 aa)
MKS1Meckel syndrome type 1 protein. (262 aa)
LOC102743151RING finger protein 165-like. (326 aa)
LOC102740547Bone morphogenetic protein 4-like isoform X1. (409 aa)
LOC102727981Homeobox protein aristaless-like 4-like. (278 aa)
PITX1Homeobox protein. (312 aa)
LOC102742062T-box transcription factor TBX5-like. (308 aa)
LOC102727186Heart- and neural crest derivatives-expressed protein 2-like. (217 aa)
LOC102750229Homeobox protein Hox-C13-like. (364 aa)
SHHSonic hedgehog protein-like. (286 aa)
LOC102733867Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (235 aa)
LOC102744116Interferon regulatory factor 6-like. (227 aa)
KREMEN2Kremen protein 2-like. (307 aa)
LOC102731463Transcription factor AP-2-beta-like. (180 aa)
LOC102734560plexin-A2-like. (296 aa)
LOC102734562Inositol monophosphatase 3-like. (171 aa)
LOC102734830Endothelin-converting enzyme 1-like. (211 aa)
ALX4Homeobox protein aristaless-like 4. (201 aa)
COMPCartilage oligomeric matrix protein. (728 aa)
MEGF8Multiple epidermal growth factor-like domains protein 8. (2068 aa)
NOTCH2Neurogenic locus notch homolog protein 2. (1238 aa)
LOC102736120Transcription factor AP-2-alpha-like. (431 aa)
MED31Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (131 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1582 aa)
GDF5Growth/differentiation factor 5. (499 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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