(13 nodes) Retinal rod cell differentiation network (Leptonychotes weddellii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	STAT3	Signal transducer and activator of transcription 3-like. (424 aa)
	NTRK2	BDNF/NT-3 growth factors receptor-like. (420 aa)
	SOX8	Transcription factor SOX-8. (412 aa)
	NRL	Neural retina-specific leucine zipper protein. (237 aa)
	LOC102745161	Signal transducer and activator of transcription 3-like. (301 aa)
	RPGRIP1L	Protein fantom isoform X2. (1244 aa)
	RPGRIP1	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1. (1266 aa)
	RORB	Nuclear receptor ROR-beta. (459 aa)
	CNTF	Ciliary neurotrophic factor. (199 aa)
	LOC102750488	Oxygen-regulated protein 1-like. (2144 aa)
	LOC102738369	Merlin-like. (110 aa)
	LOC102727345	Transcription factor SOX-9-like. (282 aa)
	LOC102741496	BDNF/NT-3 growth factors receptor-like. (97 aa)

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CNTF	LOC102745161	A0A2U3XAU3	A0A2U3Y4I5	Ciliary neurotrophic factor.	Signal transducer and activator of transcription 3-like.	0.508
CNTF	STAT3	A0A2U3XAU3	A0A2U3Z463	Ciliary neurotrophic factor.	Signal transducer and activator of transcription 3-like.	0.563
LOC102741496	NTRK2	A0A2U3Y6P9	A0A2U3Y6N6	BDNF/NT-3 growth factors receptor-like.	BDNF/NT-3 growth factors receptor-like.	0.900
LOC102745161	CNTF	A0A2U3Y4I5	A0A2U3XAU3	Signal transducer and activator of transcription 3-like.	Ciliary neurotrophic factor.	0.508
LOC102745161	STAT3	A0A2U3Y4I5	A0A2U3Z463	Signal transducer and activator of transcription 3-like.	Signal transducer and activator of transcription 3-like.	0.950
LOC102750488	NRL	A0A2U3XA72	A0A2U3Y516	Oxygen-regulated protein 1-like.	Neural retina-specific leucine zipper protein.	0.472
NRL	LOC102750488	A0A2U3Y516	A0A2U3XA72	Neural retina-specific leucine zipper protein.	Oxygen-regulated protein 1-like.	0.472
NTRK2	LOC102741496	A0A2U3Y6N6	A0A2U3Y6P9	BDNF/NT-3 growth factors receptor-like.	BDNF/NT-3 growth factors receptor-like.	0.900
RPGRIP1	RPGRIP1L	A0A2U3XIV2	A0A2U3XME4	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1.	Protein fantom isoform X2.	0.402
RPGRIP1L	RPGRIP1	A0A2U3XME4	A0A2U3XIV2	Protein fantom isoform X2.	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1.	0.402
STAT3	CNTF	A0A2U3Z463	A0A2U3XAU3	Signal transducer and activator of transcription 3-like.	Ciliary neurotrophic factor.	0.563
STAT3	LOC102745161	A0A2U3Z463	A0A2U3Y4I5	Signal transducer and activator of transcription 3-like.	Signal transducer and activator of transcription 3-like.	0.950