STRINGSTRING
MPP2 MPP2 LOC102746549 LOC102746549 SYT12 SYT12 LOC102743561 LOC102743561 STX3 STX3 GRIN2D GRIN2D MAPK1 MAPK1 LRRTM2 LRRTM2 MECP2 MECP2 LOC102741496 LOC102741496 NTRK2 NTRK2 PRRT1 PRRT1 LOC102737493 LOC102737493 GFAP GFAP GRIN2A GRIN2A RGS14 RGS14 PTEN PTEN NOG NOG SLC24A1 SLC24A1 NR2E1 NR2E1 LRRTM1 LRRTM1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MPP2MAGUK p55 subfamily member 2; Belongs to the MAGUK family. (413 aa)
LOC102746549Glutamate receptor ionotropic, NMDA 2C-like. (348 aa)
SYT12Synaptotagmin-12. (419 aa)
LOC102743561Corticotropin-releasing factor receptor 2-like. (76 aa)
STX3Syntaxin-3; Belongs to the syntaxin family. (285 aa)
GRIN2DGlutamate receptor ionotropic, NMDA 2D. (840 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (326 aa)
LRRTM2Leucine-rich repeat transmembrane neuronal protein 2 isoform X1. (516 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (499 aa)
LOC102741496BDNF/NT-3 growth factors receptor-like. (97 aa)
NTRK2BDNF/NT-3 growth factors receptor-like. (420 aa)
PRRT1Proline-rich transmembrane protein 1. (306 aa)
LOC102737493Synaptosomal-associated protein; Belongs to the SNAP-25 family. (143 aa)
GFAPGlial fibrillary acidic protein isoform X1; Belongs to the intermediate filament family. (432 aa)
GRIN2AGlutamate receptor ionotropic, NMDA 2A. (1308 aa)
RGS14Regulator of G-protein signaling 14. (85 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
SLC24A1Sodium/potassium/calcium exchanger 1 isoform X1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (1109 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (385 aa)
LRRTM1Leucine-rich repeat transmembrane neuronal protein 1-like. (522 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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