STRINGSTRING
SGPL1 SGPL1 CHD7 CHD7 TIPARP TIPARP CRISPLD1 CRISPLD1 LEF1 LEF1 LOC102729478 LOC102729478 ANKRD11 ANKRD11 RRAS RRAS ALDH1A2 ALDH1A2 MSX1 MSX1 MAPK1 MAPK1 ZIC3 ZIC3 PDGFRA PDGFRA RARG RARG ALDH1A3 ALDH1A3 RAF1 RAF1 HOXB3 HOXB3 SRF SRF LOC102747185 LOC102747185 TGFB3 TGFB3 PTPN11 PTPN11 CSRNP1 CSRNP1 NIPBL NIPBL EP300 EP300 NOG NOG LOC102729222 LOC102729222 LOC102745028 LOC102745028 LOC102742272 LOC102742272
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SGPL1Sphingosine-1-phosphate lyase 1. (568 aa)
CHD7chromodomain-helicase-DNA-binding protein 7. (2429 aa)
TIPARPTCDD-inducible poly [ADP-ribose] polymerase. (657 aa)
CRISPLD1Cysteine-rich secretory protein LCCL domain-containing 1 isoform X1. (500 aa)
LEF1Lymphoid enhancer-binding factor 1 isoform X1. (399 aa)
LOC102729478Endothelin-1 receptor-like; Belongs to the G-protein coupled receptor 1 family. (253 aa)
ANKRD11Ankyrin repeat domain-containing protein 11. (2595 aa)
RRASRas-related protein R-Ras. (218 aa)
ALDH1A2Retinal dehydrogenase 2 isoform X1; Belongs to the aldehyde dehydrogenase family. (518 aa)
MSX1Homeobox protein MSX-1. (303 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (326 aa)
ZIC3Zinc finger protein ZIC 3. (465 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1090 aa)
RARGRetinoic acid receptor gamma isoform X1. (486 aa)
ALDH1A3Aldehyde dehydrogenase family 1 member A3; Belongs to the aldehyde dehydrogenase family. (261 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase isoform X1. (648 aa)
HOXB3Homeobox protein Hox-B3. (211 aa)
SRFSerum response factor. (508 aa)
LOC102747185Homeobox protein DLX-5-like. (214 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
CSRNP1Cysteine/serine-rich nuclear protein 1. (582 aa)
NIPBLNipped-B protein. (2803 aa)
EP300Histone acetyltransferase p300. (2425 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
LOC102729222Schwannomin-interacting protein 1-like. (146 aa)
LOC102745028Endothelin-1 receptor-like. (178 aa)
LOC102742272Aldehyde dehydrogenase family 1 member A3-like. (127 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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