(13 nodes) Innervation network (Leptonychotes weddellii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GABRA5	Gamma-aminobutyric acid receptor subunit alpha-5; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (463 aa)
	CHD7	chromodomain-helicase-DNA-binding protein 7. (2429 aa)
	SULF1	Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (867 aa)
	NPTX1	Neuronal pentraxin-1. (432 aa)
	LOC102728321	High affinity nerve growth factor receptor-like. (109 aa)
	FBXO45	F-box/SPRY domain-containing protein 1. (286 aa)
	SULF2	N-acetylglucosamine-6-sulfatase. (412 aa)
	LOC102729478	Endothelin-1 receptor-like; Belongs to the G-protein coupled receptor 1 family. (253 aa)
	NTRK1	Tyrosine-protein kinase receptor. (592 aa)
	LOC102734830	Endothelin-converting enzyme 1-like. (211 aa)
	LOC102743151	RING finger protein 165-like. (326 aa)
	NTF4	Neurotrophin-4; Belongs to the NGF-beta family. (211 aa)
	LOC102745028	Endothelin-1 receptor-like. (178 aa)

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC102728321	NTF4	A0A2U3XZA5	A0A2U3Z3T9	High affinity nerve growth factor receptor-like.	Neurotrophin-4; Belongs to the NGF-beta family.	0.901
LOC102728321	NTRK1	A0A2U3XZA5	A0A2U3YYL0	High affinity nerve growth factor receptor-like.	Tyrosine-protein kinase receptor.	0.455
LOC102729478	LOC102734830	A0A2U3YS39	A0A2U3YYX4	Endothelin-1 receptor-like; Belongs to the G-protein coupled receptor 1 family.	Endothelin-converting enzyme 1-like.	0.493
LOC102729478	LOC102745028	A0A2U3YS39	A0A2U3Z7H5	Endothelin-1 receptor-like; Belongs to the G-protein coupled receptor 1 family.	Endothelin-1 receptor-like.	0.900
LOC102734830	LOC102729478	A0A2U3YYX4	A0A2U3YS39	Endothelin-converting enzyme 1-like.	Endothelin-1 receptor-like; Belongs to the G-protein coupled receptor 1 family.	0.493
LOC102734830	LOC102745028	A0A2U3YYX4	A0A2U3Z7H5	Endothelin-converting enzyme 1-like.	Endothelin-1 receptor-like.	0.493
LOC102745028	LOC102729478	A0A2U3Z7H5	A0A2U3YS39	Endothelin-1 receptor-like.	Endothelin-1 receptor-like; Belongs to the G-protein coupled receptor 1 family.	0.900
LOC102745028	LOC102734830	A0A2U3Z7H5	A0A2U3YYX4	Endothelin-1 receptor-like.	Endothelin-converting enzyme 1-like.	0.493
NTF4	LOC102728321	A0A2U3Z3T9	A0A2U3XZA5	Neurotrophin-4; Belongs to the NGF-beta family.	High affinity nerve growth factor receptor-like.	0.901
NTF4	NTRK1	A0A2U3Z3T9	A0A2U3YYL0	Neurotrophin-4; Belongs to the NGF-beta family.	Tyrosine-protein kinase receptor.	0.901
NTRK1	LOC102728321	A0A2U3YYL0	A0A2U3XZA5	Tyrosine-protein kinase receptor.	High affinity nerve growth factor receptor-like.	0.455
NTRK1	NTF4	A0A2U3YYL0	A0A2U3Z3T9	Tyrosine-protein kinase receptor.	Neurotrophin-4; Belongs to the NGF-beta family.	0.901