(24 nodes) Lung epithelium development network (Leptonychotes weddellii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CREB1	Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
	LOC102740547	Bone morphogenetic protein 4-like isoform X1. (409 aa)
	RCN3	Reticulocalbin-3. (328 aa)
	YAP1	Yorkie homolog. (326 aa)
	AIMP2	Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 isoform X1. (320 aa)
	ERRFI1	ERBB receptor feedback inhibitor 1. (460 aa)
	FNDC3B	Fibronectin type III domain-containing protein 3B. (1155 aa)
	LOC102727345	Transcription factor SOX-9-like. (282 aa)
	LOC102749599	Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (420 aa)
	ADAMTSL2	ADAMTS-like protein 2. (955 aa)
	NKX2-1	Homeobox protein Nkx-2.1. (252 aa)
	SPDEF	SAM pointed domain-containing Ets transcription factor. (335 aa)
	AGR2	Anterior gradient protein 2 homolog isoform X1. (175 aa)
	NKX2-2	Homeobox protein Nkx-2.2. (273 aa)
	GATA6	Transcription factor GATA-6. (287 aa)
	HOXA5	Homeobox protein Hox-A5. (270 aa)
	TMEM38B	Trimeric intracellular cation channel type B. (291 aa)
	SAV1	Protein salvador homolog 1. (384 aa)
	RBBP9	Putative hydrolase RBBP9. (186 aa)
	PPP3R1	Calcineurin subunit B type 1 isoform X1. (170 aa)
	FOXA1	Hepatocyte nuclear factor 3-alpha. (473 aa)
	FGF10	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (218 aa)
	FOXJ1	Forkhead box protein J1. (421 aa)
	KRAS	GTPase KRas isoform X2. (188 aa)

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGR2	FOXA1	A0A2U3XXS6	A0A2U3XEU1	Anterior gradient protein 2 homolog isoform X1.	Hepatocyte nuclear factor 3-alpha.	0.448
AGR2	SPDEF	A0A2U3XXS6	A0A2U3Y066	Anterior gradient protein 2 homolog isoform X1.	SAM pointed domain-containing Ets transcription factor.	0.580
FGF10	FOXJ1	A0A2U3XE64	A0A2U3X9J3	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Forkhead box protein J1.	0.406
FGF10	KRAS	A0A2U3XE64	A0A2U3X8L4	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	GTPase KRas isoform X2.	0.616
FGF10	LOC102727345	A0A2U3XE64	A0A2U3YND0	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Transcription factor SOX-9-like.	0.509
FGF10	LOC102740547	A0A2U3XE64	A0A2U3Z034	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Bone morphogenetic protein 4-like isoform X1.	0.769
FGF10	NKX2-1	A0A2U3XE64	A0A2U3YB70	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Homeobox protein Nkx-2.1.	0.489
FOXA1	AGR2	A0A2U3XEU1	A0A2U3XXS6	Hepatocyte nuclear factor 3-alpha.	Anterior gradient protein 2 homolog isoform X1.	0.448
FOXA1	GATA6	A0A2U3XEU1	A0A2U3XNQ5	Hepatocyte nuclear factor 3-alpha.	Transcription factor GATA-6.	0.794
FOXA1	NKX2-1	A0A2U3XEU1	A0A2U3YB70	Hepatocyte nuclear factor 3-alpha.	Homeobox protein Nkx-2.1.	0.581
FOXA1	NKX2-2	A0A2U3XEU1	A0A2U3XNW3	Hepatocyte nuclear factor 3-alpha.	Homeobox protein Nkx-2.2.	0.442
FOXA1	SPDEF	A0A2U3XEU1	A0A2U3Y066	Hepatocyte nuclear factor 3-alpha.	SAM pointed domain-containing Ets transcription factor.	0.407
FOXJ1	FGF10	A0A2U3X9J3	A0A2U3XE64	Forkhead box protein J1.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.406
FOXJ1	LOC102727345	A0A2U3X9J3	A0A2U3YND0	Forkhead box protein J1.	Transcription factor SOX-9-like.	0.621
FOXJ1	NKX2-1	A0A2U3X9J3	A0A2U3YB70	Forkhead box protein J1.	Homeobox protein Nkx-2.1.	0.484
FOXJ1	SPDEF	A0A2U3X9J3	A0A2U3Y066	Forkhead box protein J1.	SAM pointed domain-containing Ets transcription factor.	0.488
GATA6	FOXA1	A0A2U3XNQ5	A0A2U3XEU1	Transcription factor GATA-6.	Hepatocyte nuclear factor 3-alpha.	0.794
GATA6	LOC102727345	A0A2U3XNQ5	A0A2U3YND0	Transcription factor GATA-6.	Transcription factor SOX-9-like.	0.512
GATA6	LOC102740547	A0A2U3XNQ5	A0A2U3Z034	Transcription factor GATA-6.	Bone morphogenetic protein 4-like isoform X1.	0.593
GATA6	NKX2-1	A0A2U3XNQ5	A0A2U3YB70	Transcription factor GATA-6.	Homeobox protein Nkx-2.1.	0.454