STRINGSTRING
LOC102745732 LOC102745732 LRRC1 LRRC1 VDR VDR FGF10 FGF10 LOC102741253 LOC102741253 SRC SRC SOSTDC1 SOSTDC1 PHB2 PHB2 PTCH1 PTCH1 TBX3 TBX3 KDM5B KDM5B PML PML MST1 MST1 DDR1 DDR1 CSF1 CSF1 MED1 MED1 NTN1 NTN1 LOC102730307 LOC102730307
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC102745732Leucine-rich repeat-containing protein 1-like. (92 aa)
LRRC1Leucine-rich repeat-containing protein 1. (242 aa)
VDRVitamin D3 receptor. (427 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (218 aa)
LOC102741253Amphiregulin-like. (253 aa)
SRCTyrosine-protein kinase. (536 aa)
SOSTDC1Sclerostin domain-containing protein 1. (208 aa)
PHB2Prohibitin. (299 aa)
PTCH1Protein patched homolog 1. (1301 aa)
TBX3T-box transcription factor TBX3. (675 aa)
KDM5BLysine-specific demethylase 5B. (872 aa)
PMLProtein PML. (880 aa)
MST1Hepatocyte growth factor-like protein; Belongs to the peptidase S1 family. Plasminogen subfamily. (711 aa)
DDR1Epithelial discoidin domain-containing receptor 1 isoform X1. (921 aa)
CSF1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (547 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1582 aa)
NTN1Netrin-1-like. (402 aa)
LOC102730307CUB and sushi domain-containing protein 1-like. (828 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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