(16 nodes) Cell fate commitment involved in formation of primary germ layer network (Leptonychotes weddellii)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SFRP2	Secreted frizzled-related protein 2. (294 aa)
	CTR9	RNA polymerase-associated protein CTR9 homolog. (723 aa)
	HOXA11	Homeobox protein Hox-A11. (321 aa)
	GATA6	Transcription factor GATA-6. (287 aa)
	LEO1	RNA polymerase-associated protein LEO1. (570 aa)
	TBX6	T-box transcription factor TBX6. (436 aa)
	NANOG	Homeobox protein NANOG. (226 aa)
	EOMES	Eomesodermin homolog isoform X2. (571 aa)
	SOX17	Transcription factor SOX-17-like. (406 aa)
	ETV2	ETS translocation variant 2 isoform X1. (340 aa)
	PAF1	RNA polymerase II-associated factor 1 homolog isoform X2. (528 aa)
	EYA1	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (592 aa)
	SMAD1	Mothers against decapentaplegic homolog. (465 aa)
	NODAL	Nodal homolog. (348 aa)
	LOC102740547	Bone morphogenetic protein 4-like isoform X1. (409 aa)
	LOC102746660	RNA polymerase-associated protein CTR9 homolog. (452 aa)

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CTR9	LEO1	A0A2U3XAT8	A0A2U3XPS9	RNA polymerase-associated protein CTR9 homolog.	RNA polymerase-associated protein LEO1.	0.999
CTR9	LOC102746660	A0A2U3XAT8	A0A2U3Z2T5	RNA polymerase-associated protein CTR9 homolog.	RNA polymerase-associated protein CTR9 homolog.	0.944
CTR9	PAF1	A0A2U3XAT8	A0A2U3YIB0	RNA polymerase-associated protein CTR9 homolog.	RNA polymerase II-associated factor 1 homolog isoform X2.	0.988
EOMES	GATA6	A0A2U3YA50	A0A2U3XNQ5	Eomesodermin homolog isoform X2.	Transcription factor GATA-6.	0.579
EOMES	LOC102740547	A0A2U3YA50	A0A2U3Z034	Eomesodermin homolog isoform X2.	Bone morphogenetic protein 4-like isoform X1.	0.500
EOMES	NANOG	A0A2U3YA50	A0A2U3Y3X4	Eomesodermin homolog isoform X2.	Homeobox protein NANOG.	0.605
EOMES	NODAL	A0A2U3YA50	A0A2U3YPZ3	Eomesodermin homolog isoform X2.	Nodal homolog.	0.621
EOMES	SOX17	A0A2U3YA50	A0A2U3YER1	Eomesodermin homolog isoform X2.	Transcription factor SOX-17-like.	0.776
EYA1	LOC102740547	A0A2U3YJ16	A0A2U3Z034	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Bone morphogenetic protein 4-like isoform X1.	0.400
GATA6	EOMES	A0A2U3XNQ5	A0A2U3YA50	Transcription factor GATA-6.	Eomesodermin homolog isoform X2.	0.579
GATA6	LOC102740547	A0A2U3XNQ5	A0A2U3Z034	Transcription factor GATA-6.	Bone morphogenetic protein 4-like isoform X1.	0.593
GATA6	NANOG	A0A2U3XNQ5	A0A2U3Y3X4	Transcription factor GATA-6.	Homeobox protein NANOG.	0.826
GATA6	NODAL	A0A2U3XNQ5	A0A2U3YPZ3	Transcription factor GATA-6.	Nodal homolog.	0.544
GATA6	SOX17	A0A2U3XNQ5	A0A2U3YER1	Transcription factor GATA-6.	Transcription factor SOX-17-like.	0.888
LEO1	CTR9	A0A2U3XPS9	A0A2U3XAT8	RNA polymerase-associated protein LEO1.	RNA polymerase-associated protein CTR9 homolog.	0.999
LEO1	LOC102746660	A0A2U3XPS9	A0A2U3Z2T5	RNA polymerase-associated protein LEO1.	RNA polymerase-associated protein CTR9 homolog.	0.999
LEO1	PAF1	A0A2U3XPS9	A0A2U3YIB0	RNA polymerase-associated protein LEO1.	RNA polymerase II-associated factor 1 homolog isoform X2.	0.999
LOC102740547	EOMES	A0A2U3Z034	A0A2U3YA50	Bone morphogenetic protein 4-like isoform X1.	Eomesodermin homolog isoform X2.	0.500
LOC102740547	EYA1	A0A2U3Z034	A0A2U3YJ16	Bone morphogenetic protein 4-like isoform X1.	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.400
LOC102740547	GATA6	A0A2U3Z034	A0A2U3XNQ5	Bone morphogenetic protein 4-like isoform X1.	Transcription factor GATA-6.	0.593