(18 nodes) Coronary vasculature development network (Leptonychotes weddellii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SEC24B	Protein transport protein Sec24B isoform X1. (1258 aa)
	SGCD	Delta-sarcoglycan. (122 aa)
	DCTN5	Dynactin subunit 5. (182 aa)
	LOC102727186	Heart- and neural crest derivatives-expressed protein 2-like. (217 aa)
	LOC102750017	Mothers against decapentaplegic homolog 6-like. (181 aa)
	MEGF8	Multiple epidermal growth factor-like domains protein 8. (2068 aa)
	LOC102740547	Bone morphogenetic protein 4-like isoform X1. (409 aa)
	LOC102743063	Delta-sarcoglycan-like. (113 aa)
	GATA6	Transcription factor GATA-6. (287 aa)
	LOC102731945	Suppressor of fused homolog. (106 aa)
	MMP21	Matrix metalloproteinase-21. (465 aa)
	SRF	Serum response factor. (508 aa)
	PTK7	Inactive tyrosine-protein kinase 7 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1070 aa)
	ZBTB14	Zinc finger and BTB domain-containing protein 14. (449 aa)
	ARID2	AT-rich interactive domain-containing protein 2. (1836 aa)
	PRDM1	PR domain zinc finger protein 1 isoform X3. (818 aa)
	VEGFB	Vascular endothelial growth factor B isoform X1; Belongs to the PDGF/VEGF growth factor family. (207 aa)
	LOC102732559	Apelin receptor-like; Belongs to the G-protein coupled receptor 1 family. (380 aa)

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GATA6	LOC102727186	A0A2U3XNQ5	A0A2U3Z5T9	Transcription factor GATA-6.	Heart- and neural crest derivatives-expressed protein 2-like.	0.579
GATA6	LOC102740547	A0A2U3XNQ5	A0A2U3Z034	Transcription factor GATA-6.	Bone morphogenetic protein 4-like isoform X1.	0.593
GATA6	SRF	A0A2U3XNQ5	A0A2U3XZ49	Transcription factor GATA-6.	Serum response factor.	0.769
LOC102727186	GATA6	A0A2U3Z5T9	A0A2U3XNQ5	Heart- and neural crest derivatives-expressed protein 2-like.	Transcription factor GATA-6.	0.579
LOC102727186	LOC102740547	A0A2U3Z5T9	A0A2U3Z034	Heart- and neural crest derivatives-expressed protein 2-like.	Bone morphogenetic protein 4-like isoform X1.	0.487
LOC102740547	GATA6	A0A2U3Z034	A0A2U3XNQ5	Bone morphogenetic protein 4-like isoform X1.	Transcription factor GATA-6.	0.593
LOC102740547	LOC102727186	A0A2U3Z034	A0A2U3Z5T9	Bone morphogenetic protein 4-like isoform X1.	Heart- and neural crest derivatives-expressed protein 2-like.	0.487
LOC102740547	LOC102750017	A0A2U3Z034	A0A2U3Z1Z6	Bone morphogenetic protein 4-like isoform X1.	Mothers against decapentaplegic homolog 6-like.	0.732
LOC102743063	SGCD	A0A2U3XMM4	A0A2U3XGT9	Delta-sarcoglycan-like.	Delta-sarcoglycan.	0.957
LOC102750017	LOC102740547	A0A2U3Z1Z6	A0A2U3Z034	Mothers against decapentaplegic homolog 6-like.	Bone morphogenetic protein 4-like isoform X1.	0.732
PTK7	SEC24B	A0A2U3XZD5	A0A2U3X722	Inactive tyrosine-protein kinase 7 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Protein transport protein Sec24B isoform X1.	0.400
SEC24B	PTK7	A0A2U3X722	A0A2U3XZD5	Protein transport protein Sec24B isoform X1.	Inactive tyrosine-protein kinase 7 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.400
SGCD	LOC102743063	A0A2U3XGT9	A0A2U3XMM4	Delta-sarcoglycan.	Delta-sarcoglycan-like.	0.957
SRF	GATA6	A0A2U3XZ49	A0A2U3XNQ5	Serum response factor.	Transcription factor GATA-6.	0.769