(11 nodes) Cell surface receptor signaling pathway involved in heart development network (Leptonychotes weddellii)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
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Known Interactions

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Predicted Interactions

gene neighborhood

gene fusions

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co-expression

protein homology

Your Input:
	MSX1	Homeobox protein MSX-1. (303 aa)
	NOG	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
	SNAI1	Zinc finger protein SNAI1. (264 aa)
	LOC102747957	Meckel syndrome type 1 protein-like. (318 aa)
	JAG1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
	WNT8A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
	BMPR1A	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
	DLL4	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
	MKS1	Meckel syndrome type 1 protein. (262 aa)
	LOC102740547	Bone morphogenetic protein 4-like isoform X1. (409 aa)
	BMP2	Bone morphogenetic protein 2-like. (395 aa)

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP2	BMPR1A	A0A2U3Z3S1	A0A2U3Y9P6	Bone morphogenetic protein 2-like.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.999
BMP2	LOC102740547	A0A2U3Z3S1	A0A2U3Z034	Bone morphogenetic protein 2-like.	Bone morphogenetic protein 4-like isoform X1.	0.898
BMP2	MSX1	A0A2U3Z3S1	A0A2U3YJR0	Bone morphogenetic protein 2-like.	Homeobox protein MSX-1.	0.415
BMP2	NOG	A0A2U3Z3S1	A0A2U3XEL8	Bone morphogenetic protein 2-like.	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	0.971
BMPR1A	BMP2	A0A2U3Y9P6	A0A2U3Z3S1	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Bone morphogenetic protein 2-like.	0.999
BMPR1A	LOC102740547	A0A2U3Y9P6	A0A2U3Z034	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Bone morphogenetic protein 4-like isoform X1.	0.994
BMPR1A	MSX1	A0A2U3Y9P6	A0A2U3YJR0	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Homeobox protein MSX-1.	0.595
BMPR1A	NOG	A0A2U3Y9P6	A0A2U3XEL8	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	0.688
DLL4	JAG1	A0A2U3YFQ8	A0A2U3XZY3	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.451
JAG1	DLL4	A0A2U3XZY3	A0A2U3YFQ8	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.451
JAG1	LOC102740547	A0A2U3XZY3	A0A2U3Z034	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Bone morphogenetic protein 4-like isoform X1.	0.646
JAG1	NOG	A0A2U3XZY3	A0A2U3XEL8	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	0.618
LOC102740547	BMP2	A0A2U3Z034	A0A2U3Z3S1	Bone morphogenetic protein 4-like isoform X1.	Bone morphogenetic protein 2-like.	0.898
LOC102740547	BMPR1A	A0A2U3Z034	A0A2U3Y9P6	Bone morphogenetic protein 4-like isoform X1.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.994
LOC102740547	JAG1	A0A2U3Z034	A0A2U3XZY3	Bone morphogenetic protein 4-like isoform X1.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.646
LOC102740547	MSX1	A0A2U3Z034	A0A2U3YJR0	Bone morphogenetic protein 4-like isoform X1.	Homeobox protein MSX-1.	0.595
LOC102740547	NOG	A0A2U3Z034	A0A2U3XEL8	Bone morphogenetic protein 4-like isoform X1.	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	0.992
LOC102747957	MKS1	A0A2U3XUI3	A0A2U3YYY5	Meckel syndrome type 1 protein-like.	Meckel syndrome type 1 protein.	0.934
MKS1	LOC102747957	A0A2U3YYY5	A0A2U3XUI3	Meckel syndrome type 1 protein.	Meckel syndrome type 1 protein-like.	0.934
MSX1	BMP2	A0A2U3YJR0	A0A2U3Z3S1	Homeobox protein MSX-1.	Bone morphogenetic protein 2-like.	0.415