(15 nodes) Nuclear import signal receptor activity network (Leptonychotes weddellii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	IPO4	Importin-4. (1080 aa)
	TNPO2	Transportin-2. (897 aa)
	LOC102744037	Importin subunit alpha-3-like. (241 aa)
	RANBP6	Ran-binding protein 6 isoform X1. (1105 aa)
	KPNA1	Importin subunit alpha; Functions in nuclear protein import. (538 aa)
	SNUPN	Snurportin-1 isoform X1. (368 aa)
	KPNB1	Importin subunit beta-1 isoform X3. (876 aa)
	SHISA4	Protein shisa-4. (197 aa)
	KPNA3	Importin subunit alpha; Functions in nuclear protein import. (497 aa)
	KPNA2	Importin subunit alpha; Functions in nuclear protein import. (529 aa)
	TMCO6	Transmembrane and coiled-coil domain-containing protein 6. (493 aa)
	LOC102729442	Protein Hikeshi. (197 aa)
	IPO5	Importin-5 isoform X1. (1097 aa)
	KPNA5	Importin subunit alpha; Functions in nuclear protein import. (539 aa)
	LOC102750113	Importin subunit alpha; Functions in nuclear protein import. (523 aa)

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
IPO4	IPO5	A0A2U3Y7C5	A0A2U3XSH7	Importin-4.	Importin-5 isoform X1.	0.808
IPO4	KPNA1	A0A2U3Y7C5	A0A2U3YI58	Importin-4.	Importin subunit alpha; Functions in nuclear protein import.	0.491
IPO4	KPNA2	A0A2U3Y7C5	A0A2U3XDN0	Importin-4.	Importin subunit alpha; Functions in nuclear protein import.	0.490
IPO4	KPNA5	A0A2U3Y7C5	A0A2U3XT32	Importin-4.	Importin subunit alpha; Functions in nuclear protein import.	0.452
IPO4	KPNB1	A0A2U3Y7C5	A0A2U3YMK7	Importin-4.	Importin subunit beta-1 isoform X3.	0.789
IPO4	LOC102744037	A0A2U3Y7C5	A0A2U3Y883	Importin-4.	Importin subunit alpha-3-like.	0.569
IPO4	RANBP6	A0A2U3Y7C5	A0A2U3YF57	Importin-4.	Ran-binding protein 6 isoform X1.	0.763
IPO4	TNPO2	A0A2U3Y7C5	A0A2U3Z3W4	Importin-4.	Transportin-2.	0.789
IPO5	IPO4	A0A2U3XSH7	A0A2U3Y7C5	Importin-5 isoform X1.	Importin-4.	0.808
IPO5	KPNA1	A0A2U3XSH7	A0A2U3YI58	Importin-5 isoform X1.	Importin subunit alpha; Functions in nuclear protein import.	0.450
IPO5	KPNA2	A0A2U3XSH7	A0A2U3XDN0	Importin-5 isoform X1.	Importin subunit alpha; Functions in nuclear protein import.	0.526
IPO5	KPNA3	A0A2U3XSH7	A0A2U3Y0E8	Importin-5 isoform X1.	Importin subunit alpha; Functions in nuclear protein import.	0.417
IPO5	KPNA5	A0A2U3XSH7	A0A2U3XT32	Importin-5 isoform X1.	Importin subunit alpha; Functions in nuclear protein import.	0.442
IPO5	KPNB1	A0A2U3XSH7	A0A2U3YMK7	Importin-5 isoform X1.	Importin subunit beta-1 isoform X3.	0.743
IPO5	LOC102729442	A0A2U3XSH7	A0A2U3XXT0	Importin-5 isoform X1.	Protein Hikeshi.	0.744
IPO5	TNPO2	A0A2U3XSH7	A0A2U3Z3W4	Importin-5 isoform X1.	Transportin-2.	0.728
KPNA1	IPO4	A0A2U3YI58	A0A2U3Y7C5	Importin subunit alpha; Functions in nuclear protein import.	Importin-4.	0.491
KPNA1	IPO5	A0A2U3YI58	A0A2U3XSH7	Importin subunit alpha; Functions in nuclear protein import.	Importin-5 isoform X1.	0.450
KPNA1	KPNA2	A0A2U3YI58	A0A2U3XDN0	Importin subunit alpha; Functions in nuclear protein import.	Importin subunit alpha; Functions in nuclear protein import.	0.558
KPNA1	KPNA3	A0A2U3YI58	A0A2U3Y0E8	Importin subunit alpha; Functions in nuclear protein import.	Importin subunit alpha; Functions in nuclear protein import.	0.952