(47 nodes) Intracellular protein transmembrane transport network (Leptonychotes weddellii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC102730527	Breakpoint cluster region protein-like. (172 aa)
	PEX2	Peroxisome biogenesis factor 2 isoform X1. (305 aa)
	HSPD1	60 kDa heat shock protein, mitochondrial isoform X1; Belongs to the chaperonin (HSP60) family. (573 aa)
	LOC102735345	Mitochondrial import receptor subunit TOM7 homolog. (55 aa)
	TOMM70A	Mitochondrial import receptor subunit TOM70. (609 aa)
	SEC61G	Protein transport protein Sec61 subunit gamma. (68 aa)
	DNAJC15	dnaJ homolog subfamily C member 15. (149 aa)
	DNAJC19	Mitochondrial import inner membrane translocase subunit TIM14. (116 aa)
	LOC102734246	Uncharacterized protein C3orf18 homolog isoform X1. (162 aa)
	FAM185A	Protein FAM185A. (387 aa)
	PEX10	Peroxisome biogenesis factor 10. (326 aa)
	PEX1	Peroxisome biogenesis factor 1 isoform X1. (1262 aa)
	PEX13	Peroxisomal membrane protein PEX13. (403 aa)
	LOC102734059	Apoptosis-inducing factor 1, mitochondrial-like. (145 aa)
	LOC102738778	Apoptosis-inducing factor 1, mitochondrial-like. (210 aa)
	GRPEL1	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family. (232 aa)
	PEX6	Peroxisome assembly factor 2 isoform X1. (980 aa)
	LOC102742298	Peroxisomal targeting signal 1 receptor-like. (323 aa)
	PEX5	Peroxisomal targeting signal 1 receptor-like. (349 aa)
	TIMM17B	Mitochondrial import inner membrane translocase subunit TIM17; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (172 aa)
	RTN2	Reticulon. (474 aa)
	LOC102735487	Translocating chain-associated membrane protein; Belongs to the TRAM family. (370 aa)
	TIMM17A	Mitochondrial import inner membrane translocase subunit TIM17; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (162 aa)
	GRPEL2	grpE protein homolog 2, mitochondrial. (113 aa)
	TIMM21	Mitochondrial import inner membrane translocase subunit Tim21. (244 aa)
	LONP2	Lon protease homolog 2, peroxisomal. (660 aa)
	ZFAND2B	AN1-type zinc finger protein 2B isoform X2. (258 aa)
	LOC102728044	Protein transport protein Sec61 subunit gamma-like. (81 aa)
	TIMM50	Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (355 aa)
	SEC63	Translocation protein SEC63 homolog. (760 aa)
	LOC102744979	DNL-type zinc finger protein-like. (102 aa)
	TOMM20L	TOMM20-like protein 1. (152 aa)
	PEX12	Peroxisome assembly protein 12; Required for protein import into peroxisomes. Belongs to the pex2/pex10/pex12 family. (359 aa)
	HSPA5	78 kDa glucose-regulated protein isoform X2; Belongs to the heat shock protein 70 family. (654 aa)
	LOC102738323	Mitochondrial import receptor subunit TOM40B-like. (142 aa)
	LOC102750571	Peroxisomal membrane protein PEX14-like. (239 aa)
	TOMM20	Mitochondrial import receptor subunit TOM20 homolog. (145 aa)
	LOC102735720	Mitochondrial import receptor subunit TOM40B-like. (145 aa)
	PEX7	Peroxisomal targeting signal 2 receptor. (354 aa)
	TOMM40	Mitochondrial import receptor subunit TOM40 homolog isoform X1. (361 aa)
	TRAM2	Translocating chain-associated membrane protein; Belongs to the TRAM family. (370 aa)
	CHCHD4	Mitochondrial intermembrane space import and assembly protein 40. (141 aa)
	LOC102746860	Apoptosis-inducing factor 1, mitochondrial-like. (232 aa)
	ROMO1	Reactive oxygen species modulator 1 isoform X1. (79 aa)
	SEC61A1	Protein transport protein Sec61 subunit alpha isoform 1. (415 aa)
	PEX14	Peroxisomal membrane protein PEX14. (99 aa)
	LOC102746352	Lon protease homolog 2, peroxisomal-like; Belongs to the peptidase S16 family. (206 aa)

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHCHD4	TIMM17A	A0A2U3YYG4	A0A2U3Y7M1	Mitochondrial intermembrane space import and assembly protein 40.	Mitochondrial import inner membrane translocase subunit TIM17; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.	0.405
CHCHD4	TIMM21	A0A2U3YYG4	A0A2U3YG68	Mitochondrial intermembrane space import and assembly protein 40.	Mitochondrial import inner membrane translocase subunit Tim21.	0.497
CHCHD4	TIMM50	A0A2U3YYG4	A0A2U3YIP0	Mitochondrial intermembrane space import and assembly protein 40.	Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.	0.502
CHCHD4	TOMM70A	A0A2U3YYG4	A0A2U3XDT5	Mitochondrial intermembrane space import and assembly protein 40.	Mitochondrial import receptor subunit TOM70.	0.517
DNAJC15	GRPEL1	A0A2U3XGT2	A0A2U3XXF8	dnaJ homolog subfamily C member 15.	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.	0.642
DNAJC15	GRPEL2	A0A2U3XGT2	A0A2U3YAL7	dnaJ homolog subfamily C member 15.	grpE protein homolog 2, mitochondrial.	0.596
DNAJC15	LOC102735345	A0A2U3XGT2	A0A2U3XDD5	dnaJ homolog subfamily C member 15.	Mitochondrial import receptor subunit TOM7 homolog.	0.423
DNAJC15	TIMM17A	A0A2U3XGT2	A0A2U3Y7M1	dnaJ homolog subfamily C member 15.	Mitochondrial import inner membrane translocase subunit TIM17; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.	0.701
DNAJC15	TIMM17B	A0A2U3XGT2	A0A2U3Y3Z2	dnaJ homolog subfamily C member 15.	Mitochondrial import inner membrane translocase subunit TIM17; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.	0.548
DNAJC15	TIMM21	A0A2U3XGT2	A0A2U3YG68	dnaJ homolog subfamily C member 15.	Mitochondrial import inner membrane translocase subunit Tim21.	0.518
DNAJC15	TIMM50	A0A2U3XGT2	A0A2U3YIP0	dnaJ homolog subfamily C member 15.	Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.	0.495
DNAJC19	GRPEL1	A0A2U3XIZ4	A0A2U3XXF8	Mitochondrial import inner membrane translocase subunit TIM14.	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.	0.512
DNAJC19	GRPEL2	A0A2U3XIZ4	A0A2U3YAL7	Mitochondrial import inner membrane translocase subunit TIM14.	grpE protein homolog 2, mitochondrial.	0.512
DNAJC19	LOC102735345	A0A2U3XIZ4	A0A2U3XDD5	Mitochondrial import inner membrane translocase subunit TIM14.	Mitochondrial import receptor subunit TOM7 homolog.	0.423
DNAJC19	TIMM17A	A0A2U3XIZ4	A0A2U3Y7M1	Mitochondrial import inner membrane translocase subunit TIM14.	Mitochondrial import inner membrane translocase subunit TIM17; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.	0.649
DNAJC19	TIMM17B	A0A2U3XIZ4	A0A2U3Y3Z2	Mitochondrial import inner membrane translocase subunit TIM14.	Mitochondrial import inner membrane translocase subunit TIM17; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.	0.556
DNAJC19	TIMM21	A0A2U3XIZ4	A0A2U3YG68	Mitochondrial import inner membrane translocase subunit TIM14.	Mitochondrial import inner membrane translocase subunit Tim21.	0.623
DNAJC19	TIMM50	A0A2U3XIZ4	A0A2U3YIP0	Mitochondrial import inner membrane translocase subunit TIM14.	Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.	0.632
FAM185A	LOC102742298	A0A2U3XKH4	A0A2U3Y2M4	Protein FAM185A.	Peroxisomal targeting signal 1 receptor-like.	0.829
FAM185A	PEX1	A0A2U3XKH4	A0A2U3XML0	Protein FAM185A.	Peroxisome biogenesis factor 1 isoform X1.	0.728