STRINGSTRING
SHH SHH LOC102748833 LOC102748833 IL4I1 IL4I1 NF1 NF1 PLA2G2F PLA2G2F LOC102740547 LOC102740547 LOC102745732 LOC102745732 LGALS9 LGALS9 CRTAM CRTAM LOC102734445 LOC102734445 CTLA4 CTLA4 LOC102727257 LOC102727257 LRRC32 LRRC32 TNFRSF14 TNFRSF14 BLK BLK PRNP PRNP ATM ATM LOC102726821 LOC102726821 FOXP3 FOXP3 TYROBP TYROBP TWSG1 TWSG1 PRKAR1A PRKAR1A NDFIP1 NDFIP1 ARG2 ARG2 IL2 IL2 PKN1 PKN1 BTK BTK PDCD1LG2 PDCD1LG2 BCL6 BCL6 MARCH7 MARCH7 PAWR PAWR LOC102741183 LOC102741183 DLG2 DLG2 IL10 IL10 CLEC4G CLEC4G VSIG4 VSIG4 PTEN PTEN IDO1 IDO1 CEBPB CEBPB LOC102749335 LOC102749335 CD80 CD80 GREM1 GREM1 GPNMB GPNMB GLMN GLMN RASSF5 RASSF5 CBLB CBLB LRRC1 LRRC1 CD300A CD300A FOXJ1 FOXJ1 TNFRSF21 TNFRSF21 KIAA0922 KIAA0922
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SHHSonic hedgehog protein-like. (286 aa)
LOC102748833Tyrosine-protein kinase. (375 aa)
IL4I1L-amino-acid oxidase. (386 aa)
NF1Neurofibromin-like. (1269 aa)
PLA2G2FPhospholipase A(2). (210 aa)
LOC102740547Bone morphogenetic protein 4-like isoform X1. (409 aa)
LOC102745732Leucine-rich repeat-containing protein 1-like. (92 aa)
LGALS9Galectin. (364 aa)
CRTAMCytotoxic and regulatory T-cell molecule. (366 aa)
LOC102734445Phospholipase A(2). (145 aa)
CTLA4Cytotoxic T-lymphocyte protein 4 isoform X1. (223 aa)
LOC102727257Tumor necrosis factor receptor superfamily member 13B-like. (270 aa)
LRRC32Leucine-rich repeat-containing protein 32. (663 aa)
TNFRSF14Tumor necrosis factor receptor superfamily member 14. (272 aa)
BLKTyrosine-protein kinase. (500 aa)
PRNPMajor prion protein; Belongs to the prion family. (257 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3054 aa)
LOC102726821Galectin. (139 aa)
FOXP3Forkhead box protein P3 isoform X1. (456 aa)
TYROBPTYRO protein tyrosine kinase-binding protein isoform X1. (111 aa)
TWSG1Twisted gastrulation protein homolog 1. (223 aa)
PRKAR1AcAMP-dependent protein kinase type I-alpha regulatory subunit. (381 aa)
NDFIP1NEDD4 family-interacting protein 1 isoform X1. (221 aa)
ARG2Arginase. (354 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (154 aa)
PKN1Serine/threonine-protein kinase N1. (796 aa)
BTKTyrosine-protein kinase. (659 aa)
PDCD1LG2Programmed cell death 1 ligand 2. (273 aa)
BCL6B-cell lymphoma 6 protein. (706 aa)
MARCH7E3 ubiquitin-protein ligase MARCH7. (695 aa)
PAWRPRKC apoptosis WT1 regulator protein. (290 aa)
LOC102741183Roquin-1-like. (688 aa)
DLG2Disks large homolog 2 isoform X1. (905 aa)
IL10Interleukin-10. (178 aa)
CLEC4GC-type lectin domain family 4 member G. (293 aa)
VSIG4V-set and immunoglobulin domain-containing protein 4 isoform X1. (399 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
IDO1Indoleamine 2,3-dioxygenase 1. (394 aa)
CEBPBCCAAT/enhancer-binding protein. (345 aa)
LOC102749335E3 ubiquitin-protein ligase CBL-B-like. (139 aa)
CD80LOW QUALITY PROTEIN: T-lymphocyte activation antigen CD80. (295 aa)
GREM1Gremlin. (184 aa)
GPNMBTransmembrane glycoprotein NMB isoform X2. (554 aa)
GLMNGlomulin. (521 aa)
RASSF5Ras association domain-containing protein 5. (194 aa)
CBLBE3 ubiquitin-protein ligase CBL-B-like. (832 aa)
LRRC1Leucine-rich repeat-containing protein 1. (242 aa)
CD300ACMRF35-like molecule 8. (309 aa)
FOXJ1Forkhead box protein J1. (421 aa)
TNFRSF21Tumor necrosis factor receptor superfamily member 21 isoform X1. (651 aa)
KIAA0922Transmembrane protein 131-like. (1601 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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