(21 nodes) Transmembrane receptor protein serine/threonine kinase binding network (Leptonychotes weddellii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NODAL	Nodal homolog. (348 aa)
	LOC102735151	Bone morphogenetic protein 7-like. (139 aa)
	LOC102747049	Signal peptide, CUB and EGF-like domain-containing protein 3-like. (624 aa)
	BMP2	Bone morphogenetic protein 2-like. (395 aa)
	LOC102750017	Mothers against decapentaplegic homolog 6-like. (181 aa)
	LOC102740157	Cadherin-5-like; Cadherins are calcium-dependent cell adhesion proteins. (464 aa)
	LOC102740547	Bone morphogenetic protein 4-like isoform X1. (409 aa)
	INHBA	Inhibin beta A chain. (424 aa)
	GDF15	Growth/differentiation factor 15. (308 aa)
	BMP6	Bone morphogenetic protein 6. (189 aa)
	BMP7	Bone morphogenetic protein 7-like. (312 aa)
	BMP8B	Bone morphogenetic protein 8B. (169 aa)
	BMP3	Bone morphogenetic protein 3; Belongs to the TGF-beta family. (475 aa)
	LOC102729648	Teratocarcinoma-derived growth factor 1-like. (184 aa)
	SYNJ2BP	Synaptojanin-2-binding protein. (145 aa)
	SRC	Tyrosine-protein kinase. (536 aa)
	SAV1	Protein salvador homolog 1. (384 aa)
	PYCARD	Apoptosis-associated speck-like protein containing a CARD isoform X1. (194 aa)
	KIAA1324L	UPF0577 protein KIAA1324-like homolog isoform X1. (915 aa)
	BMPER	BMP-binding endothelial regulator protein-like. (446 aa)
	BMP5	Bone morphogenetic protein 5 isoform X2. (454 aa)

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP2	BMP5	A0A2U3Z3S1	A0A2U3XA39	Bone morphogenetic protein 2-like.	Bone morphogenetic protein 5 isoform X2.	0.497
BMP2	BMP6	A0A2U3Z3S1	A0A2U3YPC2	Bone morphogenetic protein 2-like.	Bone morphogenetic protein 6.	0.924
BMP2	BMP7	A0A2U3Z3S1	A0A2U3YG58	Bone morphogenetic protein 2-like.	Bone morphogenetic protein 7-like.	0.592
BMP2	BMP8B	A0A2U3Z3S1	A0A2U3Y1R3	Bone morphogenetic protein 2-like.	Bone morphogenetic protein 8B.	0.488
BMP2	BMPER	A0A2U3Z3S1	A0A2U3XBU2	Bone morphogenetic protein 2-like.	BMP-binding endothelial regulator protein-like.	0.415
BMP2	LOC102735151	A0A2U3Z3S1	A0A2U3Z6A5	Bone morphogenetic protein 2-like.	Bone morphogenetic protein 7-like.	0.582
BMP2	LOC102740547	A0A2U3Z3S1	A0A2U3Z034	Bone morphogenetic protein 2-like.	Bone morphogenetic protein 4-like isoform X1.	0.898
BMP2	LOC102750017	A0A2U3Z3S1	A0A2U3Z1Z6	Bone morphogenetic protein 2-like.	Mothers against decapentaplegic homolog 6-like.	0.743
BMP2	NODAL	A0A2U3Z3S1	A0A2U3YPZ3	Bone morphogenetic protein 2-like.	Nodal homolog.	0.407
BMP5	BMP2	A0A2U3XA39	A0A2U3Z3S1	Bone morphogenetic protein 5 isoform X2.	Bone morphogenetic protein 2-like.	0.497
BMP5	LOC102740547	A0A2U3XA39	A0A2U3Z034	Bone morphogenetic protein 5 isoform X2.	Bone morphogenetic protein 4-like isoform X1.	0.650
BMP6	BMP2	A0A2U3YPC2	A0A2U3Z3S1	Bone morphogenetic protein 6.	Bone morphogenetic protein 2-like.	0.924
BMP6	BMPER	A0A2U3YPC2	A0A2U3XBU2	Bone morphogenetic protein 6.	BMP-binding endothelial regulator protein-like.	0.588
BMP6	LOC102735151	A0A2U3YPC2	A0A2U3Z6A5	Bone morphogenetic protein 6.	Bone morphogenetic protein 7-like.	0.900
BMP6	LOC102740547	A0A2U3YPC2	A0A2U3Z034	Bone morphogenetic protein 6.	Bone morphogenetic protein 4-like isoform X1.	0.944
BMP6	LOC102750017	A0A2U3YPC2	A0A2U3Z1Z6	Bone morphogenetic protein 6.	Mothers against decapentaplegic homolog 6-like.	0.571
BMP7	BMP2	A0A2U3YG58	A0A2U3Z3S1	Bone morphogenetic protein 7-like.	Bone morphogenetic protein 2-like.	0.592
BMP7	LOC102735151	A0A2U3YG58	A0A2U3Z6A5	Bone morphogenetic protein 7-like.	Bone morphogenetic protein 7-like.	0.900
BMP7	LOC102740547	A0A2U3YG58	A0A2U3Z034	Bone morphogenetic protein 7-like.	Bone morphogenetic protein 4-like isoform X1.	0.734
BMP7	LOC102750017	A0A2U3YG58	A0A2U3Z1Z6	Bone morphogenetic protein 7-like.	Mothers against decapentaplegic homolog 6-like.	0.549