(23 nodes) Cellular response to epidermal growth factor stimulus network (Leptonychotes weddellii)

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second shell of interactors

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Your Input:
	EEF1A1	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (462 aa)
	PTPN12	Tyrosine-protein phosphatase non-receptor type 12 isoform X3. (782 aa)
	PTPN11	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
	STAT5B	Signal transducer and activator of transcription 5B. (508 aa)
	ZFP36L1	Zinc finger protein 36, C3H1 type-like 1 isoform X1. (338 aa)
	VILL	Villin-like protein-like. (375 aa)
	INPP5K	Inositol polyphosphate 5-phosphatase K isoform X1. (452 aa)
	BAG4	BAG family molecular chaperone regulator 4. (421 aa)
	KNSTRN	Small kinetochore-associated protein isoform X1. (316 aa)
	ZFP36L2	Zinc finger protein 36, C3H1 type-like 2-like. (491 aa)
	ZNF259	Zinc finger protein ZPR1. (460 aa)
	ZFP36	Tristetraprolin. (325 aa)
	SNAI2	Zinc finger protein SNAI2. (268 aa)
	GAREM	GRB2-associated and regulator of MAPK protein. (753 aa)
	LOC102727345	Transcription factor SOX-9-like. (282 aa)
	LOC102737030	Receptor tyrosine-protein kinase erbB-2-like; Belongs to the protein kinase superfamily. Tyr protein kinase family. (627 aa)
	MED1	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1582 aa)
	VIL1	Villin-1. (330 aa)
	LOC102738856	Villin-like protein-like. (205 aa)
	MARS	methionine--tRNA ligase, cytoplasmic; Belongs to the class-I aminoacyl-tRNA synthetase family. (900 aa)
	LOC102741867	Villin-1-like. (505 aa)
	LOC102736146	3-phosphoinositide-dependent protein kinase 1-like. (216 aa)
	LOC102731864	Signal transducer and activator of transcription 5B-like. (353 aa)

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EEF1A1	MARS	A0A2U3XB66	A0A2U3Z416	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	methionine--tRNA ligase, cytoplasmic; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.868
EEF1A1	MED1	A0A2U3XB66	A0A2U3YTF7	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.566
EEF1A1	PTPN11	A0A2U3XB66	A0A2U3XWH5	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.500
EEF1A1	ZNF259	A0A2U3XB66	A0A2U3YIG7	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	Zinc finger protein ZPR1.	0.605
INPP5K	PTPN11	A0A2U3YCI9	A0A2U3XWH5	Inositol polyphosphate 5-phosphatase K isoform X1.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.428
LOC102727345	SNAI2	A0A2U3YND0	A0A2U3X8E1	Transcription factor SOX-9-like.	Zinc finger protein SNAI2.	0.497
LOC102731864	LOC102737030	A0A2U3Z7Y1	A0A2U3YTF2	Signal transducer and activator of transcription 5B-like.	Receptor tyrosine-protein kinase erbB-2-like; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.540
LOC102731864	PTPN11	A0A2U3Z7Y1	A0A2U3XWH5	Signal transducer and activator of transcription 5B-like.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.435
LOC102731864	STAT5B	A0A2U3Z7Y1	A0A2U3Y4J7	Signal transducer and activator of transcription 5B-like.	Signal transducer and activator of transcription 5B.	0.947
LOC102737030	LOC102731864	A0A2U3YTF2	A0A2U3Z7Y1	Receptor tyrosine-protein kinase erbB-2-like; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Signal transducer and activator of transcription 5B-like.	0.540
LOC102737030	PTPN11	A0A2U3YTF2	A0A2U3XWH5	Receptor tyrosine-protein kinase erbB-2-like; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.890
LOC102737030	PTPN12	A0A2U3YTF2	A0A2U3XKG6	Receptor tyrosine-protein kinase erbB-2-like; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Tyrosine-protein phosphatase non-receptor type 12 isoform X3.	0.557
LOC102737030	STAT5B	A0A2U3YTF2	A0A2U3Y4J7	Receptor tyrosine-protein kinase erbB-2-like; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Signal transducer and activator of transcription 5B.	0.540
LOC102738856	LOC102741867	A0A2U3Z2C5	A0A2U3Z4D4	Villin-like protein-like.	Villin-1-like.	0.899
LOC102738856	VILL	A0A2U3Z2C5	A0A2U3YBS8	Villin-like protein-like.	Villin-like protein-like.	0.899
LOC102741867	LOC102738856	A0A2U3Z4D4	A0A2U3Z2C5	Villin-1-like.	Villin-like protein-like.	0.899
LOC102741867	VIL1	A0A2U3Z4D4	A0A2U3YZ94	Villin-1-like.	Villin-1.	0.947
MARS	EEF1A1	A0A2U3Z416	A0A2U3XB66	methionine--tRNA ligase, cytoplasmic; Belongs to the class-I aminoacyl-tRNA synthetase family.	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	0.868
MARS	MED1	A0A2U3Z416	A0A2U3YTF7	methionine--tRNA ligase, cytoplasmic; Belongs to the class-I aminoacyl-tRNA synthetase family.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.554
MED1	EEF1A1	A0A2U3YTF7	A0A2U3XB66	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	0.566