(6 nodes) Podocyte development network (Leptonychotes weddellii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NOTCH2	Neurogenic locus notch homolog protein 2. (1238 aa)
	NPHS1	Nephrin. (1242 aa)
	JAG1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
	NPHS2	Podocin. (377 aa)
	LAMB2	Laminin subunit beta-2 isoform X1. (1801 aa)
	LOC102740547	Bone morphogenetic protein 4-like isoform X1. (409 aa)

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
JAG1	LOC102740547	A0A2U3XZY3	A0A2U3Z034	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Bone morphogenetic protein 4-like isoform X1.	0.646
JAG1	NOTCH2	A0A2U3XZY3	A0A2U3YXQ8	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Neurogenic locus notch homolog protein 2.	0.990
LOC102740547	JAG1	A0A2U3Z034	A0A2U3XZY3	Bone morphogenetic protein 4-like isoform X1.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.646
NOTCH2	JAG1	A0A2U3YXQ8	A0A2U3XZY3	Neurogenic locus notch homolog protein 2.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.990
NPHS1	NPHS2	A0A2U3YGQ4	A0A2U3XS05	Nephrin.	Podocin.	0.894
NPHS2	NPHS1	A0A2U3XS05	A0A2U3YGQ4	Podocin.	Nephrin.	0.894