STRINGSTRING
BCL2L1 BCL2L1 BOK BOK LOC102729504 LOC102729504 GSK3A GSK3A NF1 NF1 BCL2L2 BCL2L2 CASP2 CASP2 EYA2 EYA2 EYA1 EYA1 LOC102746004 LOC102746004 GSK3B GSK3B BCL2A1 BCL2A1 KITLG KITLG IL2 IL2 BAK1 BAK1 FADD FADD FGF10 FGF10 FOXO3 FOXO3 COL2A1 COL2A1 ERBB3 ERBB3 MCL1 MCL1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BCL2L1Bcl-2-like protein 1 isoform X1. (233 aa)
BOKBcl-2-related ovarian killer protein. (213 aa)
LOC102729504Apoptosis regulator BAX-like. (212 aa)
GSK3AGlycogen synthase kinase-3 alpha; Belongs to the protein kinase superfamily. (419 aa)
NF1Neurofibromin-like. (1269 aa)
BCL2L2Bcl-2-like protein 2 isoform X1. (193 aa)
CASP2Caspase-2; Belongs to the peptidase C14A family. (312 aa)
EYA2Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (251 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (592 aa)
LOC102746004Bcl-2-like protein 11-like isoform X2. (140 aa)
GSK3BGlycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa)
BCL2A1Bcl-2-related protein A1. (174 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (274 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (154 aa)
BAK1Bcl-2 homologous antagonist/killer. (211 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (218 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (218 aa)
FOXO3Forkhead box protein O3. (672 aa)
COL2A1Collagen alpha-1(II) chain isoform X1. (1487 aa)
ERBB3Receptor tyrosine-protein kinase erbB-3. (1339 aa)
MCL1Induced myeloid leukemia cell differentiation protein Mcl-1 homolog isoform X1. (350 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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