STRINGSTRING
AGTR2 AGTR2 CAV1 CAV1 LOC102747630 LOC102747630 GJA5 GJA5 ARHGAP42 ARHGAP42 ADRA2B ADRA2B HRH2 HRH2 DRD1 DRD1 LOC102734862 LOC102734862 PLOD3 PLOD3 HTR2B HTR2B BMPR2 BMPR2 F2R F2R F2RL1 F2RL1 NPPA NPPA ADRA2A ADRA2A BDKRB2 BDKRB2 LOC102739889 LOC102739889 LOC102738191 LOC102738191 ADRA1A ADRA1A ITGB1BP1 ITGB1BP1 HTR1D HTR1D HTR7 HTR7 TBXA2R TBXA2R ATG5 ATG5 LOC102741200 LOC102741200 UTS2R UTS2R PRKG1 PRKG1 SERPINF2 SERPINF2 AVPR1B AVPR1B HTR1A HTR1A EDN2 EDN2 KNG1 KNG1 GRIP2 GRIP2 UCN UCN ZDHHC21 ZDHHC21 ADRA1D ADRA1D GCLC GCLC ADRA1B ADRA1B DBH DBH LOC102729478 LOC102729478 DRD5 DRD5 COMP COMP ABL1 ABL1 CBS CBS BBS2 BBS2 GPER1 GPER1 LOC102727681 LOC102727681 LOC102730623 LOC102730623 INS INS AGT AGT P2RY2 P2RY2 LOC102729925 LOC102729925 LOC102732556 LOC102732556 LOC102741172 LOC102741172 LOC102744509 LOC102744509 LOC102745028 LOC102745028 LOC102735756 LOC102735756
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AGTR2Type-2 angiotensin II receptor; Belongs to the G-protein coupled receptor 1 family. (361 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
LOC1027476305-hydroxytryptamine receptor 1B-like. (389 aa)
GJA5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (358 aa)
ARHGAP42Rho GTPase-activating protein 42. (874 aa)
ADRA2Balpha-2B adrenergic receptor. (444 aa)
HRH2Histamine H2 receptor; Belongs to the G-protein coupled receptor 1 family. (359 aa)
DRD1D(1A) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (446 aa)
LOC102734862Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa)
PLOD3Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3. (741 aa)
HTR2B5-hydroxytryptamine receptor 2B. (526 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (974 aa)
F2RProteinase-activated receptor 1; Belongs to the G-protein coupled receptor 1 family. (427 aa)
F2RL1Proteinase-activated receptor 2. (415 aa)
NPPANatriuretic peptides A. (150 aa)
ADRA2Aalpha-2A adrenergic receptor. (350 aa)
BDKRB2B2 bradykinin receptor; Belongs to the G-protein coupled receptor 1 family. (392 aa)
LOC102739889Dedicator of cytokinesis protein 4-like. (137 aa)
LOC102738191Dedicator of cytokinesis protein 4-like isoform X1; Belongs to the DOCK family. (846 aa)
ADRA1Aalpha-1A adrenergic receptor. (465 aa)
ITGB1BP1Integrin beta-1-binding protein 1 isoform X1. (200 aa)
HTR1D5-hydroxytryptamine receptor 1D. (377 aa)
HTR75-hydroxytryptamine receptor 7. (435 aa)
TBXA2RThromboxane A2 receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (343 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (255 aa)
LOC102741200Exostosin-1-like; Belongs to the glycosyltransferase 47 family. (746 aa)
UTS2RUrotensin-2 receptor; Belongs to the G-protein coupled receptor 1 family. (384 aa)
PRKG1cGMP-dependent protein kinase 1. (193 aa)
SERPINF2Alpha-2-antiplasmin; Belongs to the serpin family. (415 aa)
AVPR1BVasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (420 aa)
HTR1A5-hydroxytryptamine receptor 1A. (422 aa)
EDN2Endothelin-2. (179 aa)
KNG1Kininogen-1 isoform X1. (652 aa)
GRIP2Glutamate receptor-interacting protein 2. (919 aa)
UCNUrocortin. (126 aa)
ZDHHC21Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (265 aa)
ADRA1Dalpha-1D adrenergic receptor. (509 aa)
GCLCGlutamate--cysteine ligase catalytic subunit-like isoform X1. (637 aa)
ADRA1Balpha-1B adrenergic receptor. (345 aa)
DBHDopamine beta-hydroxylase. (274 aa)
LOC102729478Endothelin-1 receptor-like; Belongs to the G-protein coupled receptor 1 family. (253 aa)
DRD5D(1B) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (432 aa)
COMPCartilage oligomeric matrix protein. (728 aa)
ABL1Tyrosine-protein kinase ABL1-like. (312 aa)
CBSCystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (572 aa)
BBS2Bardet-Biedl syndrome 2 protein-like. (603 aa)
GPER1G-protein coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (370 aa)
LOC102727681Exostosin-2-like. (142 aa)
LOC102730623Beta-2 adrenergic receptor-like. (418 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
AGTAngiotensinogen; Belongs to the serpin family. (477 aa)
P2RY2P2Y purinoceptor 2; Belongs to the G-protein coupled receptor 1 family. (377 aa)
LOC102729925B1 bradykinin receptor-like. (343 aa)
LOC102732556Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (590 aa)
LOC102741172Carbamoyl-phosphate synthase [ammonia], mitochondrial-like. (179 aa)
LOC102744509Autophagy protein 5-like. (78 aa)
LOC102745028Endothelin-1 receptor-like. (178 aa)
LOC102735756alpha-1B adrenergic receptor-like. (213 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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