(25 nodes) Protein complex involved in cell adhesion network (Leptonychotes weddellii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ITGA5	Integrin alpha-5; Belongs to the integrin alpha chain family. (1054 aa)
	ITGA7	Integrin alpha-7; Belongs to the integrin alpha chain family. (1181 aa)
	ITGAD	Integrin alpha-D; Belongs to the integrin alpha chain family. (1160 aa)
	ITGAX	Integrin alpha-X; Belongs to the integrin alpha chain family. (1166 aa)
	ITGAM	Integrin alpha-M isoform X1; Belongs to the integrin alpha chain family. (1154 aa)
	ITGA10	LOW QUALITY PROTEIN: integrin alpha-10; Belongs to the integrin alpha chain family. (1165 aa)
	LOC102727373	Integrin alpha-10-like. (374 aa)
	CD80	LOW QUALITY PROTEIN: T-lymphocyte activation antigen CD80. (295 aa)
	VTN	Vitronectin. (456 aa)
	PLAUR	Urokinase plasminogen activator surface receptor isoform X1. (335 aa)
	ITGB3	Integrin beta; Belongs to the integrin beta chain family. (852 aa)
	ITGB1	Integrin beta; Belongs to the integrin beta chain family. (798 aa)
	ITGAL	Integrin alpha-L; Belongs to the integrin alpha chain family. (1168 aa)
	LOC102749767	Integrin alpha-IIb-like. (534 aa)
	LOC102744445	Integrin beta; Belongs to the integrin beta chain family. (197 aa)
	ITGA4	Integrin alpha-4; Belongs to the integrin alpha chain family. (1033 aa)
	LGALS2	Galectin. (130 aa)
	LGALS1	Galectin. (135 aa)
	LOC102739404	Integrin alpha-9-like. (152 aa)
	ITGA9	Integrin alpha-9-like. (470 aa)
	ITGB7	Integrin beta; Belongs to the integrin beta chain family. (763 aa)
	EMILIN1	EMILIN-1-like. (1013 aa)
	LOC102741220	Integrin alpha-9-like. (114 aa)
	CD28	T-cell-specific surface glycoprotein CD28. (209 aa)
	CTLA4	Cytotoxic T-lymphocyte protein 4 isoform X1. (223 aa)

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD28	CD80	A0A2U3YTM8	A0A2U3XGM7	T-cell-specific surface glycoprotein CD28.	LOW QUALITY PROTEIN: T-lymphocyte activation antigen CD80.	0.984
CD28	CTLA4	A0A2U3YTM8	A0A2U3YTN6	T-cell-specific surface glycoprotein CD28.	Cytotoxic T-lymphocyte protein 4 isoform X1.	0.589
CD80	CD28	A0A2U3XGM7	A0A2U3YTM8	LOW QUALITY PROTEIN: T-lymphocyte activation antigen CD80.	T-cell-specific surface glycoprotein CD28.	0.984
CD80	CTLA4	A0A2U3XGM7	A0A2U3YTN6	LOW QUALITY PROTEIN: T-lymphocyte activation antigen CD80.	Cytotoxic T-lymphocyte protein 4 isoform X1.	0.999
CD80	ITGAL	A0A2U3XGM7	A0A2U3Y2T7	LOW QUALITY PROTEIN: T-lymphocyte activation antigen CD80.	Integrin alpha-L; Belongs to the integrin alpha chain family.	0.634
CD80	ITGAM	A0A2U3XGM7	A0A2U3XF06	LOW QUALITY PROTEIN: T-lymphocyte activation antigen CD80.	Integrin alpha-M isoform X1; Belongs to the integrin alpha chain family.	0.531
CD80	ITGAX	A0A2U3XGM7	A0A2U3XEP9	LOW QUALITY PROTEIN: T-lymphocyte activation antigen CD80.	Integrin alpha-X; Belongs to the integrin alpha chain family.	0.531
CD80	ITGB1	A0A2U3XGM7	A0A2U3Y1P5	LOW QUALITY PROTEIN: T-lymphocyte activation antigen CD80.	Integrin beta; Belongs to the integrin beta chain family.	0.496
CTLA4	CD28	A0A2U3YTN6	A0A2U3YTM8	Cytotoxic T-lymphocyte protein 4 isoform X1.	T-cell-specific surface glycoprotein CD28.	0.589
CTLA4	CD80	A0A2U3YTN6	A0A2U3XGM7	Cytotoxic T-lymphocyte protein 4 isoform X1.	LOW QUALITY PROTEIN: T-lymphocyte activation antigen CD80.	0.999
ITGA10	ITGA4	A0A2U3XFD9	A0A2U3YB92	LOW QUALITY PROTEIN: integrin alpha-10; Belongs to the integrin alpha chain family.	Integrin alpha-4; Belongs to the integrin alpha chain family.	0.532
ITGA10	ITGA5	A0A2U3XFD9	A0A2U3XBB2	LOW QUALITY PROTEIN: integrin alpha-10; Belongs to the integrin alpha chain family.	Integrin alpha-5; Belongs to the integrin alpha chain family.	0.651
ITGA10	ITGA7	A0A2U3XFD9	A0A2U3XBE3	LOW QUALITY PROTEIN: integrin alpha-10; Belongs to the integrin alpha chain family.	Integrin alpha-7; Belongs to the integrin alpha chain family.	0.684
ITGA10	ITGA9	A0A2U3XFD9	A0A2U3YBR3	LOW QUALITY PROTEIN: integrin alpha-10; Belongs to the integrin alpha chain family.	Integrin alpha-9-like.	0.514
ITGA10	ITGAD	A0A2U3XFD9	A0A2U3XEL7	LOW QUALITY PROTEIN: integrin alpha-10; Belongs to the integrin alpha chain family.	Integrin alpha-D; Belongs to the integrin alpha chain family.	0.481
ITGA10	ITGAL	A0A2U3XFD9	A0A2U3Y2T7	LOW QUALITY PROTEIN: integrin alpha-10; Belongs to the integrin alpha chain family.	Integrin alpha-L; Belongs to the integrin alpha chain family.	0.543
ITGA10	ITGAM	A0A2U3XFD9	A0A2U3XF06	LOW QUALITY PROTEIN: integrin alpha-10; Belongs to the integrin alpha chain family.	Integrin alpha-M isoform X1; Belongs to the integrin alpha chain family.	0.472
ITGA10	ITGAX	A0A2U3XFD9	A0A2U3XEP9	LOW QUALITY PROTEIN: integrin alpha-10; Belongs to the integrin alpha chain family.	Integrin alpha-X; Belongs to the integrin alpha chain family.	0.472
ITGA10	ITGB1	A0A2U3XFD9	A0A2U3Y1P5	LOW QUALITY PROTEIN: integrin alpha-10; Belongs to the integrin alpha chain family.	Integrin beta; Belongs to the integrin beta chain family.	0.969
ITGA10	ITGB3	A0A2U3XFD9	A0A2U3XSL7	LOW QUALITY PROTEIN: integrin alpha-10; Belongs to the integrin alpha chain family.	Integrin beta; Belongs to the integrin beta chain family.	0.872