STRINGSTRING
CALCRL CALCRL LOC102726335 LOC102726335 B2M B2M GRIK2 GRIK2 GRIN3A GRIN3A ACVR2A ACVR2A OLFM3 OLFM3 ITGA5 ITGA5 ITGA7 ITGA7 ERBB3 ERBB3 CACNG5 CACNG5 CACNG4 CACNG4 ITGAD ITGAD ITGAX ITGAX ITGAM ITGAM ITGA10 ITGA10 LOC102727373 LOC102727373 CD79A CD79A TLR6 TLR6 GRIA2 GRIA2 ACVR2B ACVR2B GRID2 GRID2 ZAP70 ZAP70 GRIK4 GRIK4 ITGB3 ITGB3 GRIN2A GRIN2A CHRNA9 CHRNA9 ACVR1C ACVR1C CHRNB2 CHRNB2 ACVR1 ACVR1 HTRA2 HTRA2 HTR3A HTR3A IL23R IL23R CD247 CD247 STXBP5 STXBP5 GRM1 GRM1 RAMP3 RAMP3 TRAF6 TRAF6 CACNG7 CACNG7 IL18R1 IL18R1 GRIN1 GRIN1 DLG3 DLG3 ITGB1 ITGB1 CD79B CD79B ITGAL ITGAL IGF1R IGF1R PORCN PORCN RNF31 RNF31 LOC102749767 LOC102749767 CHRNB1 CHRNB1 DLG4 DLG4 STOML2 STOML2 LOC102749673 LOC102749673 LOC102736905 LOC102736905 LOC102744445 LOC102744445 CHRNA7 CHRNA7 ITGA4 ITGA4 LOC102739404 LOC102739404 ITGA9 ITGA9 LOC102730162 LOC102730162 ITGB7 ITGB7 LOC102734398 LOC102734398 AMHR2 AMHR2 CD3D CD3D LOC102731583 LOC102731583 GPR156 GPR156 CSF2RB CSF2RB LOC102729256 LOC102729256 EMILIN1 EMILIN1 ACVRL1 ACVRL1 LOC102740611 LOC102740611 LOC102730789 LOC102730789 INSRR INSRR LOC102741220 LOC102741220 GRIN2D GRIN2D VWC2L VWC2L CACNG2 CACNG2 HFE2 HFE2 ABHD6 ABHD6 GRIA1 GRIA1 CHRNA2 CHRNA2 CHRNB4 CHRNB4 LOC102731850 LOC102731850 CHRND CHRND RAMP2 RAMP2 BMP2 BMP2 LOC102746549 LOC102746549 CSF2 CSF2 LOC102732364 LOC102732364 TFR2 TFR2
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CALCRLCalcitonin gene-related peptide type 1 receptor; Belongs to the G-protein coupled receptor 2 family. (410 aa)
LOC102726335Glutamate receptor ionotropic, delta-2-like isoform X1. (787 aa)
B2MBeta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (118 aa)
GRIK2Glutamate receptor ionotropic, kainate 2-like. (841 aa)
GRIN3AGlutamate receptor ionotropic, NMDA 3A. (1115 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
OLFM3Noelin-3 isoform X1. (478 aa)
ITGA5Integrin alpha-5; Belongs to the integrin alpha chain family. (1054 aa)
ITGA7Integrin alpha-7; Belongs to the integrin alpha chain family. (1181 aa)
ERBB3Receptor tyrosine-protein kinase erbB-3. (1339 aa)
CACNG5Voltage-dependent calcium channel gamma-5 subunit. (275 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (327 aa)
ITGADIntegrin alpha-D; Belongs to the integrin alpha chain family. (1160 aa)
ITGAXIntegrin alpha-X; Belongs to the integrin alpha chain family. (1166 aa)
ITGAMIntegrin alpha-M isoform X1; Belongs to the integrin alpha chain family. (1154 aa)
ITGA10LOW QUALITY PROTEIN: integrin alpha-10; Belongs to the integrin alpha chain family. (1165 aa)
LOC102727373Integrin alpha-10-like. (374 aa)
CD79AB-cell antigen receptor complex-associated protein alpha chain isoform X1. (236 aa)
TLR6Toll-like receptor. (794 aa)
GRIA2Glutamate receptor 2 isoform X1. (940 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (434 aa)
GRID2Glutamate receptor ionotropic, delta-2. (211 aa)
ZAP70Tyrosine-protein kinase. (616 aa)
GRIK4Glutamate receptor ionotropic, kainate 4. (956 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (852 aa)
GRIN2AGlutamate receptor ionotropic, NMDA 2A. (1308 aa)
CHRNA9Neuronal acetylcholine receptor subunit alpha-9. (479 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (443 aa)
CHRNB2Neuronal acetylcholine receptor subunit beta-2. (510 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
HTRA2Serine protease HTRA2, mitochondrial isoform X1. (458 aa)
HTR3A5-hydroxytryptamine receptor 3A; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (483 aa)
IL23RInterleukin-23 receptor. (631 aa)
CD247T-cell surface glycoprotein CD3 zeta chain. (166 aa)
STXBP5Syntaxin-binding protein 5 isoform X1. (1152 aa)
GRM1Metabotropic glutamate receptor 1. (887 aa)
RAMP3Receptor activity-modifying protein 3. (116 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa)
CACNG7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa)
IL18R1Interleukin-18 receptor 1. (540 aa)
GRIN1Glutamate receptor ionotropic, NMDA 1 isoform X1. (943 aa)
DLG3Disks large homolog 3 isoform X1; Belongs to the MAGUK family. (512 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
CD79BB-cell antigen receptor complex-associated protein beta chain isoform X1. (222 aa)
ITGALIntegrin alpha-L; Belongs to the integrin alpha chain family. (1168 aa)
IGF1RInsulin-like growth factor 1 receptor-like. (291 aa)
PORCNProtein-cysteine N-palmitoyltransferase porcupine isoform X1; Belongs to the membrane-bound acyltransferase family. (461 aa)
RNF31E3 ubiquitin-protein ligase RNF31 isoform X1. (1080 aa)
LOC102749767Integrin alpha-IIb-like. (534 aa)
CHRNB1Acetylcholine receptor subunit beta. (504 aa)
DLG4Disks large homolog 4 isoform X1; Belongs to the MAGUK family. (764 aa)
STOML2Stomatin-like protein 2, mitochondrial isoform X1. (356 aa)
LOC102749673Insulin-like growth factor 1 receptor-like. (143 aa)
LOC102736905Glutamate receptor 3-like. (89 aa)
LOC102744445Integrin beta; Belongs to the integrin beta chain family. (197 aa)
CHRNA7Neuronal acetylcholine receptor subunit alpha-7-like isoform X2. (499 aa)
ITGA4Integrin alpha-4; Belongs to the integrin alpha chain family. (1033 aa)
LOC102739404Integrin alpha-9-like. (152 aa)
ITGA9Integrin alpha-9-like. (470 aa)
LOC102730162T-cell surface glycoprotein CD3 gamma chain-like. (182 aa)
ITGB7Integrin beta; Belongs to the integrin beta chain family. (763 aa)
LOC102734398T-cell surface glycoprotein CD3 gamma chain-like. (167 aa)
AMHR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (583 aa)
CD3DT-cell surface glycoprotein CD3 delta chain. (171 aa)
LOC102731583Voltage-dependent calcium channel gamma-3 subunit-like. (315 aa)
GPR156Probable G-protein coupled receptor 156 isoform X1. (815 aa)
CSF2RBCytokine receptor common subunit beta. (902 aa)
LOC102729256TNF receptor-associated factor 3-like. (283 aa)
EMILIN1EMILIN-1-like. (1013 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
LOC102740611TNF receptor-associated factor. (490 aa)
LOC102730789TNF receptor-associated factor 3-like. (295 aa)
INSRRTyrosine-protein kinase receptor. (1380 aa)
LOC102741220Integrin alpha-9-like. (114 aa)
GRIN2DGlutamate receptor ionotropic, NMDA 2D. (840 aa)
VWC2LVon Willebrand factor C domain-containing protein 2-like. (222 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (252 aa)
HFE2Hemojuvelin-like isoform X1. (428 aa)
ABHD6Monoacylglycerol lipase ABHD6. (337 aa)
GRIA1Glutamate receptor 1-like; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (528 aa)
CHRNA2Neuronal acetylcholine receptor subunit alpha-2 isoform X1. (495 aa)
CHRNB4Neuronal acetylcholine receptor subunit beta-4. (498 aa)
LOC102731850Tyrosine-protein kinase receptor. (757 aa)
CHRNDAcetylcholine receptor subunit delta isoform X1. (517 aa)
RAMP2Receptor activity-modifying protein 2. (118 aa)
BMP2Bone morphogenetic protein 2-like. (395 aa)
LOC102746549Glutamate receptor ionotropic, NMDA 2C-like. (348 aa)
CSF2Granulocyte-macrophage colony-stimulating factor. (153 aa)
LOC102732364Brorin-like. (133 aa)
TFR2Transferrin receptor protein 2-like. (641 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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