(31 nodes) Regulation of cell-substrate junction organization network (Leptonychotes weddellii)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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Predicted Interactions

gene neighborhood

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Your Input:
	S100A10	Protein S100-A10; Belongs to the S-100 family. (97 aa)
	PTPRJ	Receptor-type tyrosine-protein phosphatase eta-like. (1218 aa)
	ARF6	ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
	GREM1	Gremlin. (184 aa)
	LOC102728392	ephrin-A5-like; Belongs to the ephrin family. (191 aa)
	LOC102726679	Protein S100-A10-like; Belongs to the S-100 family. (97 aa)
	LOC102726171	LIM domain-binding protein 1-like. (190 aa)
	LOC102732851	LIM domain-binding protein 1-like. (227 aa)
	PTEN	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
	LOC102734862	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa)
	CORO1C	coronin-1C. (303 aa)
	VCL	Vinculin isoform X1. (1134 aa)
	FERMT2	Fermitin family homolog 2 isoform X1. (687 aa)
	MYOC	Myocilin. (490 aa)
	LAMTOR2	Ragulator complex protein LAMTOR2 isoform X1. (125 aa)
	TEK	Angiopoietin-1 receptor isoform X1. (1125 aa)
	ITGB1BP1	Integrin beta-1-binding protein 1 isoform X1. (200 aa)
	THY1	Thy-1 membrane glycoprotein. (161 aa)
	ACVRL1	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
	PPM1F	Protein phosphatase 1F. (287 aa)
	SLK	STE20-like serine/threonine-protein kinase isoform X1. (1241 aa)
	DMTN	Dematin isoform X1. (405 aa)
	LOC102725841	Microtubule-associated protein RP/EB family member 2-like. (124 aa)
	SFRP1	Secreted frizzled-related protein 1. (303 aa)
	LOC102736516	Phosphatidylinositol 3-kinase regulatory subunit alpha-like. (138 aa)
	GPM6B	Neuronal membrane glycoprotein M6-b. (153 aa)
	ABL1	Tyrosine-protein kinase ABL1-like. (312 aa)
	LOC102740057	Vascular endothelial growth factor A-like isoform X1; Belongs to the PDGF/VEGF growth factor family. (186 aa)
	LOC102730108	Neuropilin-1-like. (465 aa)
	LOC102751021	Phosphatidylinositol 3-kinase regulatory subunit alpha-like isoform X1. (454 aa)
	LOC102730129	Uncharacterized protein LOC102730129. (471 aa)

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABL1	LOC102736516	A0A2U3YZ15	A0A2U3YU20	Tyrosine-protein kinase ABL1-like.	Phosphatidylinositol 3-kinase regulatory subunit alpha-like.	0.423
ABL1	LOC102751021	A0A2U3YZ15	A0A2U3Z893	Tyrosine-protein kinase ABL1-like.	Phosphatidylinositol 3-kinase regulatory subunit alpha-like isoform X1.	0.423
ABL1	VCL	A0A2U3YZ15	A0A2U3XPV4	Tyrosine-protein kinase ABL1-like.	Vinculin isoform X1.	0.571
FERMT2	PPM1F	A0A2U3XVZ1	A0A2U3YIV5	Fermitin family homolog 2 isoform X1.	Protein phosphatase 1F.	0.474
FERMT2	VCL	A0A2U3XVZ1	A0A2U3XPV4	Fermitin family homolog 2 isoform X1.	Vinculin isoform X1.	0.667
LOC102726171	LOC102732851	A0A2U3XI31	A0A2U3XIK9	LIM domain-binding protein 1-like.	LIM domain-binding protein 1-like.	0.922
LOC102728392	LOC102730108	A0A2U3XG39	A0A2U3Z2Y2	ephrin-A5-like; Belongs to the ephrin family.	Neuropilin-1-like.	0.483
LOC102730108	LOC102728392	A0A2U3Z2Y2	A0A2U3XG39	Neuropilin-1-like.	ephrin-A5-like; Belongs to the ephrin family.	0.483
LOC102730108	LOC102730129	A0A2U3Z2Y2	A0A2U3Z8I1	Neuropilin-1-like.	Uncharacterized protein LOC102730129.	0.637
LOC102730108	LOC102740057	A0A2U3Z2Y2	A0A2U3Z228	Neuropilin-1-like.	Vascular endothelial growth factor A-like isoform X1; Belongs to the PDGF/VEGF growth factor family.	0.637
LOC102730108	TEK	A0A2U3Z2Y2	A0A2U3Y080	Neuropilin-1-like.	Angiopoietin-1 receptor isoform X1.	0.559
LOC102730129	LOC102730108	A0A2U3Z8I1	A0A2U3Z2Y2	Uncharacterized protein LOC102730129.	Neuropilin-1-like.	0.637
LOC102730129	LOC102740057	A0A2U3Z8I1	A0A2U3Z228	Uncharacterized protein LOC102730129.	Vascular endothelial growth factor A-like isoform X1; Belongs to the PDGF/VEGF growth factor family.	0.899
LOC102730129	PTEN	A0A2U3Z8I1	A0A2U3XMX7	Uncharacterized protein LOC102730129.	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.474
LOC102730129	TEK	A0A2U3Z8I1	A0A2U3Y080	Uncharacterized protein LOC102730129.	Angiopoietin-1 receptor isoform X1.	0.903
LOC102732851	LOC102726171	A0A2U3XIK9	A0A2U3XI31	LIM domain-binding protein 1-like.	LIM domain-binding protein 1-like.	0.922
LOC102734862	PTEN	A0A2U3XNQ7	A0A2U3XMX7	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.942
LOC102734862	VCL	A0A2U3XNQ7	A0A2U3XPV4	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	Vinculin isoform X1.	0.516
LOC102736516	ABL1	A0A2U3YU20	A0A2U3YZ15	Phosphatidylinositol 3-kinase regulatory subunit alpha-like.	Tyrosine-protein kinase ABL1-like.	0.423
LOC102736516	LOC102751021	A0A2U3YU20	A0A2U3Z893	Phosphatidylinositol 3-kinase regulatory subunit alpha-like.	Phosphatidylinositol 3-kinase regulatory subunit alpha-like isoform X1.	0.900