STRINGSTRING
S1PR4 S1PR4 HTR2A HTR2A AVPR1B AVPR1B PHB2 PHB2 NMUR1 NMUR1 HTR2B HTR2B LPAR1 LPAR1 RNASE4 RNASE4 ITK ITK LOC102735329 LOC102735329 PTH PTH GPR55 GPR55 FGF2 FGF2 ABL1 ABL1 LOC102748816 LOC102748816 PDGFRA PDGFRA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
S1PR4Sphingosine 1-phosphate receptor 4 isoform X1. (385 aa)
HTR2A5-hydroxytryptamine receptor 2A. (263 aa)
AVPR1BVasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (420 aa)
PHB2Prohibitin. (299 aa)
NMUR1neuromedin-U receptor 1; Belongs to the G-protein coupled receptor 1 family. (429 aa)
HTR2B5-hydroxytryptamine receptor 2B. (526 aa)
LPAR1Lysophosphatidic acid receptor 1 isoform X1; Belongs to the G-protein coupled receptor 1 family. (364 aa)
RNASE4Ribonuclease 4 isoform X1; Belongs to the pancreatic ribonuclease family. (147 aa)
ITKTyrosine-protein kinase. (486 aa)
LOC102735329Vascular endothelial growth factor receptor 1-like. (351 aa)
PTHParathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. (115 aa)
GPR55G-protein coupled receptor 55; Belongs to the G-protein coupled receptor 1 family. (320 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (113 aa)
ABL1Tyrosine-protein kinase ABL1-like. (312 aa)
LOC1027488165-hydroxytryptamine receptor 2A-like; Belongs to the G-protein coupled receptor 1 family. (204 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1090 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
Server load: low (10%) [HD]