STRINGSTRING
STOX1 STOX1 TREX1 TREX1 LOC102745618 LOC102745618 CTDSP1 CTDSP1 LOC102737939 LOC102737939 AMBRA1 AMBRA1 CASP2 CASP2 MBLAC1 MBLAC1 MEPCE MEPCE LOC102741471 LOC102741471 INHBA INHBA LOC102729387 LOC102729387 DCUN1D3 DCUN1D3 CDKN2A CDKN2A CDKN2B CDKN2B CCND1 CCND1 KANK2 KANK2 DACT1 DACT1 NACC2 NACC2 CDK2AP2 CDK2AP2 TM4SF5 TM4SF5 FBXO31 FBXO31 LOC102745380 LOC102745380 WAC WAC CENPJ CENPJ SDE2 SDE2 PIDD PIDD CTDSPL CTDSPL CDKN2D CDKN2D PML PML RB1 RB1 MDM2 MDM2 LOC102727937 LOC102727937 CRLF3 CRLF3 TP53 TP53 PSME3 PSME3 TFDP1 TFDP1 PSME2 PSME2 PSME1 PSME1 AIF1 AIF1 DDX3X DDX3X BCL7C BCL7C RRM2 RRM2 CPSF3 CPSF3 LOC102738400 LOC102738400 LSM10 LSM10 CRADD CRADD DDR2 DDR2 DLG2 DLG2 RBL1 RBL1 CDKN1B CDKN1B SASS6 SASS6 PTEN PTEN CDKN2C CDKN2C EZH2 EZH2 MNAT1 MNAT1 ANKRD17 ANKRD17 FGF10 FGF10 GPNMB GPNMB CCND3 CCND3 CDC73 CDC73 CCNH CCNH JADE1 JADE1 PLRG1 PLRG1 PKD2 PKD2 INO80 INO80 CDKN1A CDKN1A CUL4A CUL4A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
STOX1Storkhead-box protein 1. (881 aa)
TREX1Three prime repair exonuclease 1. (314 aa)
LOC102745618Glycosyl-phosphatidylinositol-anchored molecule-like protein-like. (120 aa)
CTDSP1Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform X2. (261 aa)
LOC102737939Transcription factor E2F7-like. (739 aa)
AMBRA1Activating molecule in BECN1-regulated autophagy protein 1-like. (299 aa)
CASP2Caspase-2; Belongs to the peptidase C14A family. (312 aa)
MBLAC1Metallo-beta-lactamase domain-containing protein 1. (250 aa)
MEPCE7SK snRNA methylphosphate capping enzyme. (702 aa)
LOC102741471Parafibromin-like. (141 aa)
INHBAInhibin beta A chain. (424 aa)
LOC102729387F-box only protein 7-like. (300 aa)
DCUN1D3DCN1-like protein. (304 aa)
CDKN2ACyclin-dependent kinase inhibitor 2A, isoforms 1/2/3. (152 aa)
CDKN2BCyclin-dependent kinase 4 inhibitor B. (138 aa)
CCND1G1/S-specific cyclin-D1; Belongs to the cyclin family. (214 aa)
KANK2KN motif and ankyrin repeat domain-containing protein 2. (419 aa)
DACT1Dapper homolog 1. (523 aa)
NACC2Nucleus accumbens-associated protein 2. (586 aa)
CDK2AP2Cyclin-dependent kinase 2-associated protein; Belongs to the CDK2AP family. (127 aa)
TM4SF5Transmembrane 4 L6 family member 5. (196 aa)
FBXO31F-box only protein 31. (397 aa)
LOC102745380Histone-lysine N-methyltransferase EZH2-like. (556 aa)
WACWW domain-containing adapter protein with coiled-coil-like isoform X1. (646 aa)
CENPJCentromere protein J. (1354 aa)
SDE2Protein SDE2 homolog. (452 aa)
PIDDP53-induced protein with a death domain. (916 aa)
CTDSPLCTD small phosphatase-like protein. (119 aa)
CDKN2DCyclin-dependent kinase 4 inhibitor D isoform X2. (166 aa)
PMLProtein PML. (880 aa)
RB1Retinoblastoma-associated protein. (846 aa)
MDM2E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (487 aa)
LOC102727937Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2-like. (249 aa)
CRLF3Cytokine receptor-like factor 3. (438 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (381 aa)
PSME3Proteasome activator complex subunit 3 isoform X3. (254 aa)
TFDP1Transcription factor. (290 aa)
PSME2Proteasome activator complex subunit 2 isoform X1. (239 aa)
PSME1Proteasome activator complex subunit 1 isoform X1. (249 aa)
AIF1Allograft inflammatory factor 1. (147 aa)
DDX3XATP-dependent RNA helicase DDX3X-like isoform X1; Belongs to the DEAD box helicase family. (662 aa)
BCL7CB-cell CLL/lymphoma 7 protein family member C. (217 aa)
RRM2Ribonucleoside-diphosphate reductase subunit M2. (392 aa)
CPSF3Cleavage and polyadenylation specificity factor subunit 3. (684 aa)
LOC102738400Annexin. (345 aa)
LSM10U7 snRNA-associated Sm-like protein LSm10 isoform X1. (123 aa)
CRADDDeath domain-containing protein CRADD. (199 aa)
DDR2Discoidin domain-containing receptor 2-like. (367 aa)
DLG2Disks large homolog 2 isoform X1. (905 aa)
RBL1Retinoblastoma-like protein 1. (1068 aa)
CDKN1BCyclin-dependent kinase inhibitor 1B. (198 aa)
SASS6Spindle assembly abnormal protein 6 homolog. (657 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
CDKN2CCyclin-dependent kinase 4 inhibitor C. (168 aa)
EZH2Histone-lysine N-methyltransferase EZH2. (144 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
ANKRD17Ankyrin repeat domain-containing protein 17. (2491 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (218 aa)
GPNMBTransmembrane glycoprotein NMB isoform X2. (554 aa)
CCND3G1/S-specific cyclin-D3 isoform X1; Belongs to the cyclin family. (291 aa)
CDC73Parafibromin. (418 aa)
CCNHcyclin-H-like; Belongs to the cyclin family. (344 aa)
JADE1Protein Jade-1 isoform X1. (843 aa)
PLRG1Pleiotropic regulator 1 isoform X1. (515 aa)
PKD2Polycystin-2. (935 aa)
INO80DNA helicase INO80-like. (350 aa)
CDKN1ACyclin-dependent kinase inhibitor 1 isoform X1. (161 aa)
CUL4ALOW QUALITY PROTEIN: cullin 4A; Belongs to the cullin family. (326 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.