STRINGSTRING
LOC102733867 LOC102733867 STK17B STK17B STK17A STK17A NUPR1 NUPR1 BTG1 BTG1 LOC102746004 LOC102746004 SFRP1 SFRP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
LOC102733867Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (235 aa)
STK17BSerine/threonine-protein kinase 17B; Belongs to the protein kinase superfamily. (372 aa)
STK17ASerine/threonine-protein kinase 17A. (201 aa)
NUPR1Nuclear protein 1 isoform X1. (82 aa)
BTG1Protein BTG1. (171 aa)
LOC102746004Bcl-2-like protein 11-like isoform X2. (140 aa)
SFRP1Secreted frizzled-related protein 1. (303 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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