STRINGSTRING
ABCD2 ABCD2 MPV17L MPV17L PON2 PON2 PON3 PON3 AATF AATF LOC102751218 LOC102751218 PINK1 PINK1 HIF1A HIF1A TP53 TP53 ATG5 ATG5 SIRT2 SIRT2 ABCD1 ABCD1 MMP3 MMP3 PARK7 PARK7 LOC102736120 LOC102736120 LOC102730527 LOC102730527 LOC102746954 LOC102746954 INS INS LOC102744509 LOC102744509
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ABCD2ATP-binding cassette sub-family D member 2 isoform X2. (742 aa)
MPV17LMpv17-like protein; Belongs to the peroxisomal membrane protein PXMP2/4 family. (191 aa)
PON2Serum paraoxonase/arylesterase 2 isoform X1. (354 aa)
PON3Serum paraoxonase/lactonase 3. (354 aa)
AATFProtein AATF. (572 aa)
LOC102751218Voltage-dependent anion-selective channel protein 1-like. (280 aa)
PINK1Serine/threonine-protein kinase PINK1, mitochondrial. (488 aa)
HIF1AHypoxia-inducible factor 1-alpha isoform X1. (823 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (381 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (255 aa)
SIRT2NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (389 aa)
ABCD1ATP-binding cassette sub-family D member 1. (825 aa)
MMP3Stromelysin-1. (476 aa)
PARK7Protein DJ-1 isoform X1. (189 aa)
LOC102736120Transcription factor AP-2-alpha-like. (431 aa)
LOC102730527Breakpoint cluster region protein-like. (172 aa)
LOC102746954Fructose-2,6-bisphosphatase TIGAR. (270 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
LOC102744509Autophagy protein 5-like. (78 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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