node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATG5 | HIF1A | A0A2U3Y6R5 | A0A2U3Y4G5 | Autophagy protein 5; Involved in autophagic vesicle formation. | Hypoxia-inducible factor 1-alpha isoform X1. | 0.461 |
ATG5 | INS | A0A2U3Y6R5 | A0A2U3Z329 | Autophagy protein 5; Involved in autophagic vesicle formation. | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.485 |
ATG5 | LOC102744509 | A0A2U3Y6R5 | A0A2U3Z6M9 | Autophagy protein 5; Involved in autophagic vesicle formation. | Autophagy protein 5-like. | 0.900 |
ATG5 | LOC102751218 | A0A2U3Y6R5 | A0A2U3XST7 | Autophagy protein 5; Involved in autophagic vesicle formation. | Voltage-dependent anion-selective channel protein 1-like. | 0.549 |
ATG5 | PINK1 | A0A2U3Y6R5 | A0A2U3Y3N8 | Autophagy protein 5; Involved in autophagic vesicle formation. | Serine/threonine-protein kinase PINK1, mitochondrial. | 0.589 |
ATG5 | TP53 | A0A2U3Y6R5 | A0A2U3Y5G3 | Autophagy protein 5; Involved in autophagic vesicle formation. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.497 |
HIF1A | ATG5 | A0A2U3Y4G5 | A0A2U3Y6R5 | Hypoxia-inducible factor 1-alpha isoform X1. | Autophagy protein 5; Involved in autophagic vesicle formation. | 0.461 |
HIF1A | INS | A0A2U3Y4G5 | A0A2U3Z329 | Hypoxia-inducible factor 1-alpha isoform X1. | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.509 |
HIF1A | SIRT2 | A0A2U3Y4G5 | A0A2U3Y6V9 | Hypoxia-inducible factor 1-alpha isoform X1. | NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. | 0.411 |
HIF1A | TP53 | A0A2U3Y4G5 | A0A2U3Y5G3 | Hypoxia-inducible factor 1-alpha isoform X1. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.871 |
INS | ATG5 | A0A2U3Z329 | A0A2U3Y6R5 | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Autophagy protein 5; Involved in autophagic vesicle formation. | 0.485 |
INS | HIF1A | A0A2U3Z329 | A0A2U3Y4G5 | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Hypoxia-inducible factor 1-alpha isoform X1. | 0.509 |
INS | TP53 | A0A2U3Z329 | A0A2U3Y5G3 | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.628 |
LOC102736120 | TP53 | A0A2U3YXA4 | A0A2U3Y5G3 | Transcription factor AP-2-alpha-like. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.427 |
LOC102744509 | ATG5 | A0A2U3Z6M9 | A0A2U3Y6R5 | Autophagy protein 5-like. | Autophagy protein 5; Involved in autophagic vesicle formation. | 0.900 |
LOC102744509 | LOC102751218 | A0A2U3Z6M9 | A0A2U3XST7 | Autophagy protein 5-like. | Voltage-dependent anion-selective channel protein 1-like. | 0.549 |
LOC102746954 | TP53 | A0A2U3Z2V1 | A0A2U3Y5G3 | Fructose-2,6-bisphosphatase TIGAR. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.951 |
LOC102751218 | ATG5 | A0A2U3XST7 | A0A2U3Y6R5 | Voltage-dependent anion-selective channel protein 1-like. | Autophagy protein 5; Involved in autophagic vesicle formation. | 0.549 |
LOC102751218 | LOC102744509 | A0A2U3XST7 | A0A2U3Z6M9 | Voltage-dependent anion-selective channel protein 1-like. | Autophagy protein 5-like. | 0.549 |
LOC102751218 | PARK7 | A0A2U3XST7 | A0A2U3YTX8 | Voltage-dependent anion-selective channel protein 1-like. | Protein DJ-1 isoform X1. | 0.470 |