(41 nodes) Regulation of stem cell differentiation network (Leptonychotes weddellii)

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Your Input:
	SOX5	Transcription factor SOX-5 isoform X2. (763 aa)
	KDM3A	Lysine-specific demethylase 3A-like. (281 aa)
	LOC102737270	Negative elongation factor B-like. (199 aa)
	STAT3	Signal transducer and activator of transcription 3-like. (424 aa)
	HNRNPU	Heterogeneous nuclear ribonucleoprotein U isoform X1. (825 aa)
	LOC102742062	T-box transcription factor TBX5-like. (308 aa)
	FGF2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (113 aa)
	SMYD5	SET and MYND domain-containing protein 5. (418 aa)
	LOC102730920	Periodic tryptophan protein 1 homolog. (166 aa)
	LOC102735433	Mitochondrial carrier homolog 2-like; Belongs to the mitochondrial carrier (TC 2.A.29) family. (279 aa)
	ABL1	Tyrosine-protein kinase ABL1-like. (312 aa)
	YAP1	Yorkie homolog. (326 aa)
	NUDT21	Cleavage and polyadenylation specificity factor subunit 5. (161 aa)
	PDGFRA	Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1090 aa)
	CDK12	Cyclin-dependent kinase 12 isoform X1. (1491 aa)
	NFE2L2	Nuclear factor erythroid 2-related factor 2 isoform X1. (590 aa)
	LOC102727345	Transcription factor SOX-9-like. (282 aa)
	ZFP36	Tristetraprolin. (325 aa)
	LOC102745380	Histone-lysine N-methyltransferase EZH2-like. (556 aa)
	ZFP36L2	Zinc finger protein 36, C3H1 type-like 2-like. (491 aa)
	GSK3B	Glycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa)
	SOX17	Transcription factor SOX-17-like. (406 aa)
	DHX36	Probable ATP-dependent RNA helicase DHX36 isoform X1. (1011 aa)
	SP7	Transcription factor Sp7 isoform X1. (431 aa)
	LTBP3	Latent-transforming growth factor beta-binding protein 3-like. (1159 aa)
	HSPA9	Stress-70 protein, mitochondrial; Belongs to the heat shock protein 70 family. (679 aa)
	TACSTD2	Tumor-associated calcium signal transducer 2. (323 aa)
	TBX3	T-box transcription factor TBX3. (675 aa)
	HOXB4	Homeobox protein Hox-B4. (107 aa)
	LOC102745161	Signal transducer and activator of transcription 3-like. (301 aa)
	NANOG	Homeobox protein NANOG. (226 aa)
	TGFB2	Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
	SETD1A	Histone-lysine N-methyltransferase SETD1A-like. (1384 aa)
	EIF2AK2	Interferon-induced, double-stranded RNA-activated protein kinase. (541 aa)
	JAG1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
	GATA6	Transcription factor GATA-6. (287 aa)
	LOC102737670	Cyclin-dependent kinase 6-like. (322 aa)
	SLC4A11	Sodium bicarbonate transporter-like protein 11. (875 aa)
	EZH2	Histone-lysine N-methyltransferase EZH2. (144 aa)
	LOC102739262	Histone-lysine N-methyltransferase SETD1A-like. (299 aa)
	LOC102730695	Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] (227 aa)

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABL1	LOC102745161	A0A2U3YZ15	A0A2U3Y4I5	Tyrosine-protein kinase ABL1-like.	Signal transducer and activator of transcription 3-like.	0.505
ABL1	STAT3	A0A2U3YZ15	A0A2U3Z463	Tyrosine-protein kinase ABL1-like.	Signal transducer and activator of transcription 3-like.	0.505
ABL1	YAP1	A0A2U3YZ15	A0A2U3YVG8	Tyrosine-protein kinase ABL1-like.	Yorkie homolog.	0.548
CDK12	LOC102737270	A0A2U3YTU7	A0A2U3Z8R4	Cyclin-dependent kinase 12 isoform X1.	Negative elongation factor B-like.	0.601
EIF2AK2	LOC102745161	A0A2U3Y1D2	A0A2U3Y4I5	Interferon-induced, double-stranded RNA-activated protein kinase.	Signal transducer and activator of transcription 3-like.	0.510
EIF2AK2	NFE2L2	A0A2U3Y1D2	A0A2U3YSZ9	Interferon-induced, double-stranded RNA-activated protein kinase.	Nuclear factor erythroid 2-related factor 2 isoform X1.	0.911
EIF2AK2	STAT3	A0A2U3Y1D2	A0A2U3Z463	Interferon-induced, double-stranded RNA-activated protein kinase.	Signal transducer and activator of transcription 3-like.	0.510
EZH2	LOC102737670	A0A2U3XHJ2	A0A2U3XML5	Histone-lysine N-methyltransferase EZH2.	Cyclin-dependent kinase 6-like.	0.462
EZH2	LOC102745161	A0A2U3XHJ2	A0A2U3Y4I5	Histone-lysine N-methyltransferase EZH2.	Signal transducer and activator of transcription 3-like.	0.517
EZH2	LOC102745380	A0A2U3XHJ2	A0A2U3YH25	Histone-lysine N-methyltransferase EZH2.	Histone-lysine N-methyltransferase EZH2-like.	0.900
EZH2	NANOG	A0A2U3XHJ2	A0A2U3Y3X4	Histone-lysine N-methyltransferase EZH2.	Homeobox protein NANOG.	0.418
EZH2	STAT3	A0A2U3XHJ2	A0A2U3Z463	Histone-lysine N-methyltransferase EZH2.	Signal transducer and activator of transcription 3-like.	0.517
FGF2	GATA6	A0A2U3Z312	A0A2U3XNQ5	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Transcription factor GATA-6.	0.475
FGF2	GSK3B	A0A2U3Z312	A0A2U3YEV1	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Glycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily.	0.507
FGF2	JAG1	A0A2U3Z312	A0A2U3XZY3	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.486
FGF2	LOC102727345	A0A2U3Z312	A0A2U3YND0	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Transcription factor SOX-9-like.	0.582
FGF2	LOC102745161	A0A2U3Z312	A0A2U3Y4I5	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Signal transducer and activator of transcription 3-like.	0.523
FGF2	NANOG	A0A2U3Z312	A0A2U3Y3X4	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Homeobox protein NANOG.	0.750
FGF2	PDGFRA	A0A2U3Z312	A0A2U3YV07	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development.	0.947
FGF2	SOX17	A0A2U3Z312	A0A2U3YER1	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Transcription factor SOX-17-like.	0.547