(10 nodes) Growth factor complex network (Leptonychotes weddellii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PDGFB	Platelet-derived growth factor subunit B isoform X1; Belongs to the PDGF/VEGF growth factor family. (241 aa)
	FGF2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (113 aa)
	VEGFB	Vascular endothelial growth factor B isoform X1; Belongs to the PDGF/VEGF growth factor family. (207 aa)
	IGFALS	Insulin-like growth factor-binding protein complex acid labile subunit. (602 aa)
	FGF17	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
	PGF	Placenta growth factor; Belongs to the PDGF/VEGF growth factor family. (170 aa)
	FGF20	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
	VEGFC	Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (419 aa)
	IGFBP6	Insulin-like growth factor-binding protein 6 isoform X1. (237 aa)
	LOC102735329	Vascular endothelial growth factor receptor 1-like. (351 aa)

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FGF17	FGF2	A0A2U3YM04	A0A2U3Z312	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.762
FGF17	LOC102735329	A0A2U3YM04	A0A2U3YU32	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Vascular endothelial growth factor receptor 1-like.	0.862
FGF17	PGF	A0A2U3YM04	A0A2U3YQ46	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Placenta growth factor; Belongs to the PDGF/VEGF growth factor family.	0.491
FGF17	VEGFC	A0A2U3YM04	A0A2U3Y8G6	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family.	0.402
FGF2	FGF17	A0A2U3Z312	A0A2U3YM04	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.762
FGF2	LOC102735329	A0A2U3Z312	A0A2U3YU32	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Vascular endothelial growth factor receptor 1-like.	0.911
FGF2	PDGFB	A0A2U3Z312	A0A2U3YT37	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Platelet-derived growth factor subunit B isoform X1; Belongs to the PDGF/VEGF growth factor family.	0.546
FGF2	PGF	A0A2U3Z312	A0A2U3YQ46	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Placenta growth factor; Belongs to the PDGF/VEGF growth factor family.	0.646
FGF2	VEGFB	A0A2U3Z312	A0A2U3YRT5	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Vascular endothelial growth factor B isoform X1; Belongs to the PDGF/VEGF growth factor family.	0.480
FGF2	VEGFC	A0A2U3Z312	A0A2U3Y8G6	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family.	0.524
FGF20	LOC102735329	A0A2U3X7J1	A0A2U3YU32	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Vascular endothelial growth factor receptor 1-like.	0.856
FGF20	PGF	A0A2U3X7J1	A0A2U3YQ46	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Placenta growth factor; Belongs to the PDGF/VEGF growth factor family.	0.491
FGF20	VEGFC	A0A2U3X7J1	A0A2U3Y8G6	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family.	0.403
LOC102735329	FGF17	A0A2U3YU32	A0A2U3YM04	Vascular endothelial growth factor receptor 1-like.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.862
LOC102735329	FGF2	A0A2U3YU32	A0A2U3Z312	Vascular endothelial growth factor receptor 1-like.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.911
LOC102735329	FGF20	A0A2U3YU32	A0A2U3X7J1	Vascular endothelial growth factor receptor 1-like.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.856
LOC102735329	PDGFB	A0A2U3YU32	A0A2U3YT37	Vascular endothelial growth factor receptor 1-like.	Platelet-derived growth factor subunit B isoform X1; Belongs to the PDGF/VEGF growth factor family.	0.929
LOC102735329	PGF	A0A2U3YU32	A0A2U3YQ46	Vascular endothelial growth factor receptor 1-like.	Placenta growth factor; Belongs to the PDGF/VEGF growth factor family.	0.960
LOC102735329	VEGFB	A0A2U3YU32	A0A2U3YRT5	Vascular endothelial growth factor receptor 1-like.	Vascular endothelial growth factor B isoform X1; Belongs to the PDGF/VEGF growth factor family.	0.990
LOC102735329	VEGFC	A0A2U3YU32	A0A2U3Y8G6	Vascular endothelial growth factor receptor 1-like.	Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family.	0.977