(21 nodes) VWFC domain network (Leptonychotes weddellii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	BMPER	BMP-binding endothelial regulator protein-like. (446 aa)
	FCGBP	LOW QUALITY PROTEIN: Fc of IgG binding protein. (2990 aa)
	CHRDL2	Chordin-like protein 2-like. (333 aa)
	LOC102745316	Von Willebrand factor-like. (532 aa)
	LOC102750303	Collagen alpha-1(I) chain-like. (395 aa)
	NOV	Protein NOV homolog. (353 aa)
	VWC2L	Von Willebrand factor C domain-containing protein 2-like. (222 aa)
	DGCR2	Integral membrane protein DGCR2/IDD isoform X2. (549 aa)
	ECM2	Extracellular matrix protein 2 isoform X1. (698 aa)
	THBS1	Thrombospondin-1 isoform X1. (1170 aa)
	LOC102738003	Protein kinase C-binding protein NELL2-like. (354 aa)
	JAG1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
	VWF	Von Willebrand factor. (2285 aa)
	OTOGL	Otogelin-like protein. (2344 aa)
	CYR61	Protein CYR61. (382 aa)
	WISP2	WNT1-inducible-signaling pathway protein 2. (203 aa)
	TECTA	Alpha-tectorin. (2155 aa)
	ZAN	Zonadhesin. (2627 aa)
	NELL2	Protein kinase C-binding protein NELL2. (376 aa)
	VWCE	Von Willebrand factor C and EGF domain-containing protein. (498 aa)
	COL2A1	Collagen alpha-1(II) chain isoform X1. (1487 aa)

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMPER	LOC102745316	A0A2U3XBU2	A0A2U3Z2D9	BMP-binding endothelial regulator protein-like.	Von Willebrand factor-like.	0.713
CHRDL2	VWCE	A0A2U3Z5T0	A0A2U3XFW2	Chordin-like protein 2-like.	Von Willebrand factor C and EGF domain-containing protein.	0.455
COL2A1	LOC102750303	A0A2U3XCY5	A0A2U3YZG6	Collagen alpha-1(II) chain isoform X1.	Collagen alpha-1(I) chain-like.	0.810
CYR61	THBS1	A0A2U3XT44	A0A2U3YEE5	Protein CYR61.	Thrombospondin-1 isoform X1.	0.544
LOC102738003	NELL2	A0A2U3YCD3	A0A2U3XG78	Protein kinase C-binding protein NELL2-like.	Protein kinase C-binding protein NELL2.	0.918
LOC102745316	BMPER	A0A2U3Z2D9	A0A2U3XBU2	Von Willebrand factor-like.	BMP-binding endothelial regulator protein-like.	0.713
LOC102745316	THBS1	A0A2U3Z2D9	A0A2U3YEE5	Von Willebrand factor-like.	Thrombospondin-1 isoform X1.	0.521
LOC102745316	VWF	A0A2U3Z2D9	A0A2U3XX42	Von Willebrand factor-like.	Von Willebrand factor.	0.951
LOC102750303	COL2A1	A0A2U3YZG6	A0A2U3XCY5	Collagen alpha-1(I) chain-like.	Collagen alpha-1(II) chain isoform X1.	0.810
LOC102750303	THBS1	A0A2U3YZG6	A0A2U3YEE5	Collagen alpha-1(I) chain-like.	Thrombospondin-1 isoform X1.	0.575
NELL2	LOC102738003	A0A2U3XG78	A0A2U3YCD3	Protein kinase C-binding protein NELL2.	Protein kinase C-binding protein NELL2-like.	0.918
THBS1	CYR61	A0A2U3YEE5	A0A2U3XT44	Thrombospondin-1 isoform X1.	Protein CYR61.	0.544
THBS1	LOC102745316	A0A2U3YEE5	A0A2U3Z2D9	Thrombospondin-1 isoform X1.	Von Willebrand factor-like.	0.521
THBS1	LOC102750303	A0A2U3YEE5	A0A2U3YZG6	Thrombospondin-1 isoform X1.	Collagen alpha-1(I) chain-like.	0.575
THBS1	VWF	A0A2U3YEE5	A0A2U3XX42	Thrombospondin-1 isoform X1.	Von Willebrand factor.	0.521
VWCE	CHRDL2	A0A2U3XFW2	A0A2U3Z5T0	Von Willebrand factor C and EGF domain-containing protein.	Chordin-like protein 2-like.	0.455
VWF	LOC102745316	A0A2U3XX42	A0A2U3Z2D9	Von Willebrand factor.	Von Willebrand factor-like.	0.951
VWF	THBS1	A0A2U3XX42	A0A2U3YEE5	Von Willebrand factor.	Thrombospondin-1 isoform X1.	0.521