(23 nodes) FERM central domain network (Leptonychotes weddellii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FRMD8	FERM domain-containing protein 8. (457 aa)
	EPB41L5	Band 4.1-like protein 5 isoform X1. (732 aa)
	FRMD4B	FERM domain-containing protein 4B-like. (339 aa)
	FERMT2	Fermitin family homolog 2 isoform X1. (687 aa)
	MSN	LOW QUALITY PROTEIN: moesin. (546 aa)
	FRMD6	FERM domain-containing protein 6-like isoform X1. (622 aa)
	FRMPD1	FERM and PDZ domain-containing protein 1. (1573 aa)
	PLEKHH1	Pleckstrin homology domain-containing family H member 1. (1365 aa)
	TLN2	Talin-2-like isoform X1. (2542 aa)
	PTPN21	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (1157 aa)
	FRMD7	FERM domain-containing protein 7. (590 aa)
	PLEKHH2	Pleckstrin homology domain-containing family H member 2. (1493 aa)
	FARP2	FERM, RhoGEF and pleckstrin domain-containing protein 2. (170 aa)
	JAK3	Tyrosine-protein kinase. (1139 aa)
	FERMT1	Fermitin family homolog 1-like. (678 aa)
	RDX	Radixin isoform X1. (572 aa)
	LOC102737163	Tyrosine-protein phosphatase non-receptor type 3-like. (442 aa)
	FRMPD3	FERM and PDZ domain-containing protein 3. (1579 aa)
	LOC102751019	Talin-1-like. (2016 aa)
	LOC102749847	Tyrosine-protein kinase JAK1-like. (444 aa)
	FRMD5	FERM domain-containing protein 5 isoform X1. (570 aa)
	EPB41L3	Band 4.1-like protein 3 isoform X1. (1095 aa)
	PLEKHH3	Pleckstrin homology domain-containing family H member 3. (728 aa)

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EPB41L3	EPB41L5	A0A2U3Y3R9	A0A2U3XY91	Band 4.1-like protein 3 isoform X1.	Band 4.1-like protein 5 isoform X1.	0.507
EPB41L5	EPB41L3	A0A2U3XY91	A0A2U3Y3R9	Band 4.1-like protein 5 isoform X1.	Band 4.1-like protein 3 isoform X1.	0.507
EPB41L5	FRMD5	A0A2U3XY91	A0A2U3X7Q5	Band 4.1-like protein 5 isoform X1.	FERM domain-containing protein 5 isoform X1.	0.480
FARP2	LOC102749847	A0A2U3YXQ1	A0A2U3Z702	FERM, RhoGEF and pleckstrin domain-containing protein 2.	Tyrosine-protein kinase JAK1-like.	0.415
FERMT1	MSN	A0A2U3Z150	A0A2U3XPG2	Fermitin family homolog 1-like.	LOW QUALITY PROTEIN: moesin.	0.470
FERMT1	RDX	A0A2U3Z150	A0A2U3Z2N7	Fermitin family homolog 1-like.	Radixin isoform X1.	0.493
FERMT2	RDX	A0A2U3XVZ1	A0A2U3Z2N7	Fermitin family homolog 2 isoform X1.	Radixin isoform X1.	0.412
FRMD4B	FRMD6	A0A2U3XY41	A0A2U3XIB8	FERM domain-containing protein 4B-like.	FERM domain-containing protein 6-like isoform X1.	0.494
FRMD5	EPB41L5	A0A2U3X7Q5	A0A2U3XY91	FERM domain-containing protein 5 isoform X1.	Band 4.1-like protein 5 isoform X1.	0.480
FRMD6	FRMD4B	A0A2U3XIB8	A0A2U3XY41	FERM domain-containing protein 6-like isoform X1.	FERM domain-containing protein 4B-like.	0.494
FRMD6	LOC102737163	A0A2U3XIB8	A0A2U3Z3D8	FERM domain-containing protein 6-like isoform X1.	Tyrosine-protein phosphatase non-receptor type 3-like.	0.427
FRMD6	MSN	A0A2U3XIB8	A0A2U3XPG2	FERM domain-containing protein 6-like isoform X1.	LOW QUALITY PROTEIN: moesin.	0.579
FRMD6	PTPN21	A0A2U3XIB8	A0A2U3YEV9	FERM domain-containing protein 6-like isoform X1.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily.	0.461
FRMD6	RDX	A0A2U3XIB8	A0A2U3Z2N7	FERM domain-containing protein 6-like isoform X1.	Radixin isoform X1.	0.579
JAK3	LOC102749847	A0A2U3Z0Y0	A0A2U3Z702	Tyrosine-protein kinase.	Tyrosine-protein kinase JAK1-like.	0.982
LOC102737163	FRMD6	A0A2U3Z3D8	A0A2U3XIB8	Tyrosine-protein phosphatase non-receptor type 3-like.	FERM domain-containing protein 6-like isoform X1.	0.427
LOC102749847	FARP2	A0A2U3Z702	A0A2U3YXQ1	Tyrosine-protein kinase JAK1-like.	FERM, RhoGEF and pleckstrin domain-containing protein 2.	0.415
LOC102749847	JAK3	A0A2U3Z702	A0A2U3Z0Y0	Tyrosine-protein kinase JAK1-like.	Tyrosine-protein kinase.	0.982
MSN	FERMT1	A0A2U3XPG2	A0A2U3Z150	LOW QUALITY PROTEIN: moesin.	Fermitin family homolog 1-like.	0.470
MSN	FRMD6	A0A2U3XPG2	A0A2U3XIB8	LOW QUALITY PROTEIN: moesin.	FERM domain-containing protein 6-like isoform X1.	0.579