STRINGSTRING
LOC102734263 LOC102734263 TAF9B TAF9B LOC102737270 LOC102737270 FIBIN FIBIN EIF3J EIF3J YARS2 YARS2 MARS2 MARS2 EIF4G2 EIF4G2 RRN3 RRN3 EEF1A1 EEF1A1 EIF2B3 EIF2B3 EIF3B EIF3B PDF PDF EARS2 EARS2 EEF2K EEF2K GFM1 GFM1 EIF4EBP3 EIF4EBP3 TAF7 TAF7 SUPT6H SUPT6H GTF2E2 GTF2E2 WARS2 WARS2 EIF4E1B EIF4E1B LARS LARS EIF4ENIF1 EIF4ENIF1 TAF6 TAF6 EIF3C EIF3C TUFM TUFM EIF3I EIF3I EIF3H EIF3H LOC102743390 LOC102743390 LOC102741681 LOC102741681 MTIF2 MTIF2 NELFE NELFE EIF3A EIF3A EIF5A2 EIF5A2 NELFA NELFA TCEAL3 TCEAL3 TCEAL8 TCEAL8 TCEAL7 TCEAL7 TCEAL5 TCEAL5 TCEAL1 TCEAL1 TAF11 TAF11 TCEB1 TCEB1 TCEA3 TCEA3 TCEANC2 TCEANC2 EEF1A2 EEF1A2 LOC102729145 LOC102729145 EIF2B5 EIF2B5 VARS VARS GTF2B GTF2B EEF2 EEF2 TAF9 TAF9 EIF5A EIF5A TEFM TEFM TAF12 TAF12 EIF4E3 EIF4E3 TSFM TSFM EIF1AD EIF1AD EIF2AK3 EIF2AK3 LARS2 LARS2 TAF3 TAF3 LOC102742208 LOC102742208 TAF13 TAF13 EIF2AK4 EIF2AK4 TCEA1 TCEA1 EIF3F EIF3F RARS RARS EIF2S3 EIF2S3 LOC102743422 LOC102743422 SUPT5H SUPT5H EIF5 EIF5 EIF1 EIF1 ELOF1 ELOF1 SEPSECS SEPSECS TAF4 TAF4 EPRS EPRS IARS2 IARS2 LOC102726827 LOC102726827 EIF1B EIF1B GATC GATC VARS2 VARS2 EEF1D EEF1D EIF2B2 EIF2B2 EIF3D EIF3D EIF4H EIF4H RARS2 RARS2 EIF3G EIF3G PET112 PET112 LOC102750675 LOC102750675 EIF2AK1 EIF2AK1 TCEANC TCEANC AARS2 AARS2 LOC102734625 LOC102734625 LOC102728279 LOC102728279 MTIF3 MTIF3 LOC102736431 LOC102736431 EIF4E2 EIF4E2 QARS QARS EIF2B4 EIF2B4 MARS MARS LOC102729820 LOC102729820 LOC102730429 LOC102730429 LOC102745131 LOC102745131 EIF4G1 EIF4G1 LOC102745331 LOC102745331 LOC102727091 LOC102727091 LOC102744935 LOC102744935 LOC102729428 LOC102729428
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
LOC102734263Translation initiation factor eIF-2B subunit alpha-like; Belongs to the eIF-2B alpha/beta/delta subunits family. (142 aa)
TAF9BTranscription initiation factor TFIID subunit 9B. (250 aa)
LOC102737270Negative elongation factor B-like. (199 aa)
FIBINFin bud initiation factor homolog. (211 aa)
EIF3JEukaryotic translation initiation factor 3 subunit J; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (211 aa)
YARS2Tyrosine--tRNA ligase. (477 aa)
MARS2methionine--tRNA ligase, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (593 aa)
EIF4G2Eukaryotic translation initiation factor 4 gamma 2 isoform X1. (701 aa)
RRN3RNA polymerase I-specific transcription initiation factor RRN3 isoform X1. (651 aa)
EEF1A1Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (462 aa)
EIF2B3Translation initiation factor eIF-2B subunit gamma. (451 aa)
EIF3BEukaryotic translation initiation factor 3 subunit B. (275 aa)
PDFPeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins; Belongs to the polypeptide deformylase family. (182 aa)
EARS2Probable glutamate--tRNA ligase, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (523 aa)
EEF2KEukaryotic elongation factor 2 kinase. (544 aa)
GFM1Elongation factor G, mitochondrial; Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. Does not mediate the disassembly of ribosomes from messenger RNA at the termination of mito [...] (754 aa)
EIF4EBP3Eukaryotic translation initiation factor 4E-binding protein 3. (101 aa)
TAF7Transcription initiation factor TFIID subunit 7. (349 aa)
SUPT6HTranscription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1726 aa)
GTF2E2Transcription initiation factor IIE subunit beta. (240 aa)
WARS2tryptophan--tRNA ligase, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (360 aa)
EIF4E1BEukaryotic translation initiation factor 4E type 1B; Belongs to the eukaryotic initiation factor 4E family. (215 aa)
LARSleucine--tRNA ligase, cytoplasmic isoform X1; Belongs to the class-I aminoacyl-tRNA synthetase family. (1178 aa)
EIF4ENIF1Eukaryotic translation initiation factor 4E transporter isoform X1. (987 aa)
TAF6Transcription initiation factor TFIID subunit 6 isoform X1. (677 aa)
EIF3CEukaryotic translation initiation factor 3 subunit C; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (913 aa)
TUFMElongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (452 aa)
EIF3IEukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (325 aa)
EIF3HEukaryotic translation initiation factor 3 subunit H. (235 aa)
LOC102743390Transcription elongation factor SPT4-like. (59 aa)
LOC102741681Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (445 aa)
MTIF2Translation initiation factor IF-2, mitochondrial. (650 aa)
NELFENegative elongation factor E isoform X1. (382 aa)
EIF3AEukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termi [...] (1308 aa)
EIF5A2Eukaryotic translation initiation factor 5A. (153 aa)
NELFANegative elongation factor A. (532 aa)
TCEAL3Transcription elongation factor A protein-like 3-like. (200 aa)
TCEAL8Transcription elongation factor A protein-like 8 isoform X1. (182 aa)
TCEAL7Transcription elongation factor A protein-like 7 isoform X2. (100 aa)
TCEAL5Transcription elongation factor A protein-like 5. (206 aa)
TCEAL1Transcription elongation factor A protein-like 1. (159 aa)
TAF11Transcription initiation factor TFIID subunit 11 isoform X1. (211 aa)
TCEB1Transcription elongation factor B polypeptide 1; Belongs to the SKP1 family. (112 aa)
TCEA3Transcription elongation factor A protein 3. (74 aa)
TCEANC2Transcription elongation factor A N-terminal and central domain-containing protein 2. (208 aa)
EEF1A2Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (463 aa)
LOC102729145Eukaryotic translation initiation factor 4 gamma 1-like. (207 aa)
EIF2B5Translation initiation factor eIF-2B subunit epsilon. (718 aa)
VARSvaline--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. (1264 aa)
GTF2BTranscription initiation factor IIB. (316 aa)
EEF2Elongation factor 2. (858 aa)
TAF9Transcription initiation factor TFIID subunit 9-like isoform X1. (265 aa)
EIF5AEukaryotic translation initiation factor 5A-1 isoform X1. (184 aa)
TEFMTranscription elongation factor, mitochondrial isoform X1. (360 aa)
TAF12Transcription initiation factor TFIID subunit 12 isoform X1. (161 aa)
EIF4E3Eukaryotic translation initiation factor 4E type 3; Belongs to the eukaryotic initiation factor 4E family. (118 aa)
TSFMElongation factor Ts, mitochondrial; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. (325 aa)
EIF1ADProbable RNA-binding protein EIF1AD. (166 aa)
EIF2AK3Eukaryotic translation initiation factor 2-alpha kinase 3 isoform X1. (1114 aa)
LARS2Probable leucine--tRNA ligase, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (664 aa)
TAF3Transcription initiation factor TFIID subunit 3. (774 aa)
LOC102742208Eukaryotic translation initiation factor 1A, X-chromosomal-like; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (144 aa)
TAF13Transcription initiation factor TFIID subunit 13. (124 aa)
EIF2AK4Eukaryotic translation initiation factor 2-alpha kinase 4. (1653 aa)
TCEA1Transcription elongation factor A protein 1 isoform X1. (301 aa)
EIF3FEukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (369 aa)
RARSarginine--tRNA ligase, cytoplasmic; Belongs to the class-I aminoacyl-tRNA synthetase family. (667 aa)
EIF2S3Eukaryotic translation initiation factor 2 subunit 3 isoform X1. (472 aa)
LOC102743422Negative elongation factor D-like. (572 aa)
SUPT5HTranscription elongation factor SPT5. (1087 aa)
EIF5Eukaryotic translation initiation factor 5. (430 aa)
EIF1Eukaryotic translation initiation factor 1. (113 aa)
ELOF1Transcription elongation factor 1 homolog; Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions. Belongs to the ELOF1 family. (83 aa)
SEPSECSO-phosphoseryl-tRNA(Sec) selenium transferase; Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl- tRNA(Sec) required for selenoprotein biosynthesis. (504 aa)
TAF4Transcription initiation factor TFIID subunit 4. (668 aa)
EPRSBifunctional glutamate/proline--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. (974 aa)
IARS2isoleucine--tRNA ligase, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (1012 aa)
LOC102726827Eukaryotic translation initiation factor 4E-like; Belongs to the eukaryotic initiation factor 4E family. (217 aa)
EIF1BEukaryotic translation initiation factor 1b. (113 aa)
GATCGlutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the GatC family. (136 aa)
VARS2valine--tRNA ligase, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (1062 aa)
EEF1DElongation factor 1-delta isoform X1; Belongs to the EF-1-beta/EF-1-delta family. (644 aa)
EIF2B2Translation initiation factor eIF-2B subunit beta; Belongs to the eIF-2B alpha/beta/delta subunits family. (351 aa)
EIF3DEukaryotic translation initiation factor 3 subunit D; mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, a complex required for several steps in the initiation of protein synthesis of a specialized repertoire of mRNAs. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl- tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required [...] (451 aa)
EIF4HEukaryotic translation initiation factor 4H isoform X1. (248 aa)
RARS2Probable arginine--tRNA ligase, mitochondrial isoform X1; Belongs to the class-I aminoacyl-tRNA synthetase family. (578 aa)
EIF3GEukaryotic translation initiation factor 3 subunit G; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termi [...] (320 aa)
PET112Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the GatB/GatE family. GatB subfamily. (557 aa)
LOC102750675Elongation factor 1-delta-like; Belongs to the EF-1-beta/EF-1-delta family. (184 aa)
EIF2AK1Eukaryotic translation initiation factor 2-alpha kinase 1 isoform X1. (630 aa)
TCEANCTranscription elongation factor A N-terminal and central domain-containing protein. (368 aa)
AARS2alanine--tRNA ligase, mitochondrial-like; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. Belongs to the class-II aminoacyl-tRNA synthetase family. (882 aa)
LOC102734625Elongation factor 1-beta-like; Belongs to the EF-1-beta/EF-1-delta family. (152 aa)
LOC102728279Eukaryotic translation elongation factor 1 epsilon-1-like. (174 aa)
MTIF3Translation initiation factor IF-3, mitochondrial. (279 aa)
LOC102736431Eukaryotic initiation factor 4A-III-like. (94 aa)
EIF4E2Eukaryotic translation initiation factor 4E type 2; Belongs to the eukaryotic initiation factor 4E family. (192 aa)
QARSglutamine--tRNA ligase isoform X2; Belongs to the class-I aminoacyl-tRNA synthetase family. (775 aa)
EIF2B4Translation initiation factor eIF-2B subunit delta isoform X1; Belongs to the eIF-2B alpha/beta/delta subunits family. (544 aa)
MARSmethionine--tRNA ligase, cytoplasmic; Belongs to the class-I aminoacyl-tRNA synthetase family. (900 aa)
LOC102729820Eukaryotic translation initiation factor 4E-binding protein 1-like. (81 aa)
LOC102730429Eukaryotic translation initiation factor 2 subunit 2-like. (214 aa)
LOC102745131Eukaryotic translation initiation factor 1A, X-chromosomal-like. (127 aa)
EIF4G1Eukaryotic translation initiation factor 4 gamma 1-like. (1415 aa)
LOC102745331Transcription initiation factor TFIID subunit 8-like. (269 aa)
LOC102727091Transcription elongation factor A protein 3-like. (103 aa)
LOC102744935Translation initiation factor eIF-2B subunit alpha-like; Belongs to the eIF-2B alpha/beta/delta subunits family. (75 aa)
LOC102729428Translation initiation factor eIF-2B subunit alpha-like; Belongs to the eIF-2B alpha/beta/delta subunits family. (114 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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