(5 nodes) Cleavage of the damaged pyrimidine network (Leptonychotes weddellii)

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Your Input:
	NEIL1	Endonuclease 8-like 1. (383 aa)
	NEIL2	Endonuclease 8-like 2. (334 aa)
	LOC102732741	uracil-DNA glycosylase-like. (177 aa)
	OGG1	N-glycosylase/DNA lyase isoform X2. (334 aa)
	NTHL1	Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. (314 aa)

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC102732741	NEIL1	A0A2U3Z2A1	A0A2U3YLP3	uracil-DNA glycosylase-like.	Endonuclease 8-like 1.	0.540
LOC102732741	NTHL1	A0A2U3Z2A1	A0A2U3YE14	uracil-DNA glycosylase-like.	Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.	0.760
LOC102732741	OGG1	A0A2U3Z2A1	A0A2U3Y5R8	uracil-DNA glycosylase-like.	N-glycosylase/DNA lyase isoform X2.	0.513
NEIL1	LOC102732741	A0A2U3YLP3	A0A2U3Z2A1	Endonuclease 8-like 1.	uracil-DNA glycosylase-like.	0.540
NEIL1	NEIL2	A0A2U3YLP3	A0A2U3XD93	Endonuclease 8-like 1.	Endonuclease 8-like 2.	0.900
NEIL1	NTHL1	A0A2U3YLP3	A0A2U3YE14	Endonuclease 8-like 1.	Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.	0.739
NEIL1	OGG1	A0A2U3YLP3	A0A2U3Y5R8	Endonuclease 8-like 1.	N-glycosylase/DNA lyase isoform X2.	0.917
NEIL2	NEIL1	A0A2U3XD93	A0A2U3YLP3	Endonuclease 8-like 2.	Endonuclease 8-like 1.	0.900
NEIL2	OGG1	A0A2U3XD93	A0A2U3Y5R8	Endonuclease 8-like 2.	N-glycosylase/DNA lyase isoform X2.	0.547
NTHL1	LOC102732741	A0A2U3YE14	A0A2U3Z2A1	Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.	uracil-DNA glycosylase-like.	0.760
NTHL1	NEIL1	A0A2U3YE14	A0A2U3YLP3	Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.	Endonuclease 8-like 1.	0.739
NTHL1	OGG1	A0A2U3YE14	A0A2U3Y5R8	Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.	N-glycosylase/DNA lyase isoform X2.	0.725
OGG1	LOC102732741	A0A2U3Y5R8	A0A2U3Z2A1	N-glycosylase/DNA lyase isoform X2.	uracil-DNA glycosylase-like.	0.513
OGG1	NEIL1	A0A2U3Y5R8	A0A2U3YLP3	N-glycosylase/DNA lyase isoform X2.	Endonuclease 8-like 1.	0.917
OGG1	NEIL2	A0A2U3Y5R8	A0A2U3XD93	N-glycosylase/DNA lyase isoform X2.	Endonuclease 8-like 2.	0.547
OGG1	NTHL1	A0A2U3Y5R8	A0A2U3YE14	N-glycosylase/DNA lyase isoform X2.	Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.	0.725