STRINGSTRING
USP14 USP14 NLRP9 NLRP9 LOC102740172 LOC102740172 LOC102746862 LOC102746862 MAPK11 MAPK11 LOC102732364 LOC102732364 LOC102735556 LOC102735556 NFKB2 NFKB2 LOC102741653 LOC102741653 S100B S100B BIRC2 BIRC2 CASP8 CASP8 PELI3 PELI3 LRRC71 LRRC71 FNBP4 FNBP4 S100A12 S100A12 NLRP13 NLRP13 LOC102747337 LOC102747337 LOC102746732 LOC102746732 BIRC3 BIRC3 LOC102733535 LOC102733535 LOC102734131 LOC102734131 UBA52 UBA52 KXD1 KXD1 LOC102732031 LOC102732031 LOC102732223 LOC102732223 LOC102732719 LOC102732719 MAP2K3 MAP2K3 TONSL TONSL FOS FOS MAPK15 MAPK15 NKIRAS1 NKIRAS1 LOC102750659 LOC102750659 LRRC14 LRRC14 LOC102743429 LOC102743429 NKIRAS2 NKIRAS2 LOC102730789 LOC102730789 LOC102737114 LOC102737114 LOC102740611 LOC102740611 APP APP IKBKB IKBKB MAPK1 MAPK1 LRRC45 LRRC45 LOC102729256 LOC102729256 CD180 CD180 PPP4R1 PPP4R1 NOD2 NOD2 LOC102730779 LOC102730779 ATF2 ATF2 USP18 USP18 NLRP6 NLRP6 LOC102748381 LOC102748381 IRF7 IRF7 RPS6KA3 RPS6KA3 LOC102739213 LOC102739213 CHUK CHUK LOC102730470 LOC102730470 LOC102728244 LOC102728244 MAP3K1 MAP3K1 NLRX1 NLRX1 KHNYN KHNYN JUN JUN NFKBIB NFKBIB IKBKG IKBKG DUSP6 DUSP6 MAPK8 MAPK8 BIRC7 BIRC7 LY96 LY96 TICAM2 TICAM2 NOD1 NOD1 FADD FADD PPP2R5D PPP2R5D TRAF6 TRAF6 TNIP2 TNIP2 LOC102735971 LOC102735971 LOC102750157 LOC102750157 AGER AGER PELI2 PELI2 TANK TANK UBE2N UBE2N ATF1 ATF1 TAB3 TAB3 LOC102729636 LOC102729636 MAP2K7 MAP2K7 CREB1 CREB1 LOC102750322 LOC102750322 NFKB1 NFKB1 NFKBIA NFKBIA MAP2K6 MAP2K6 TMEM189 TMEM189 LOC102749246 LOC102749246 MAPK7 MAPK7 DUSP7 DUSP7 PPP2CB PPP2CB KIAA1468 KIAA1468 SARM1 SARM1 LOC102728200 LOC102728200 ECSIT ECSIT MAPK10 MAPK10 LOC102749618 LOC102749618 ATF7 ATF7 IKBKE IKBKE
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
USP14Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (494 aa)
NLRP9LOW QUALITY PROTEIN: NLR family, pyrin domain containing 9. (667 aa)
LOC102740172Lipopolysaccharide-binding protein-like. (97 aa)
LOC102746862ubiquitin-40S ribosomal protein S27a-like isoform X1. (156 aa)
MAPK11Mitogen-activated protein kinase. (254 aa)
LOC102732364Brorin-like. (133 aa)
LOC102735556Mitogen-activated protein kinase 9-like. (134 aa)
NFKB2Nuclear factor NF-kappa-B p100 subunit. (900 aa)
LOC102741653Serine/threonine-protein phosphatase 4 regulatory subunit 1-like. (220 aa)
S100BProtein S100; Belongs to the S-100 family. (92 aa)
BIRC2Baculoviral IAP repeat-containing protein 2-like. (619 aa)
CASP8Caspase-8 isoform X1; Belongs to the peptidase C14A family. (486 aa)
PELI3E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (468 aa)
LRRC71Leucine-rich repeat-containing protein 71. (559 aa)
FNBP4Formin-binding protein 4 isoform X1. (1021 aa)
S100A12Protein S100; Belongs to the S-100 family. (92 aa)
NLRP13NACHT, LRR and PYD domains-containing protein 13. (991 aa)
LOC102747337ubiquitin-40S ribosomal protein S27a-like. (154 aa)
LOC102746732Ubiquitin-conjugating enzyme E2 N-like; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
BIRC3Baculoviral IAP repeat-containing protein 3. (604 aa)
LOC102733535Lymphocyte antigen 86-like. (122 aa)
LOC102734131Fos-related antigen 2-like. (241 aa)
UBA52ubiquitin-60S ribosomal protein L40 isoform X3. (128 aa)
KXD1kxDL motif-containing protein 1 isoform X1. (176 aa)
LOC102732031Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform-like. (407 aa)
LOC102732223Toll/interleukin-1 receptor domain-containing adapter protein-like. (226 aa)
LOC102732719Ribosomal protein S6 kinase alpha-1-like. (200 aa)
MAP2K3Dual specificity mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa)
TONSLTonsoku-like protein. (879 aa)
FOSProto-oncogene c-Fos isoform X1. (380 aa)
MAPK15Mitogen-activated protein kinase. (559 aa)
NKIRAS1NF-kappa-B inhibitor-interacting Ras-like protein 1 isoform X1. (192 aa)
LOC102750659Tonsoku-like protein-like. (490 aa)
LRRC14Leucine-rich repeat-containing protein 14. (503 aa)
LOC102743429Leucine-rich repeat-containing protein LOC400891-like. (392 aa)
NKIRAS2NF-kappa-B inhibitor-interacting Ras-like protein 2 isoform X2. (191 aa)
LOC102730789TNF receptor-associated factor 3-like. (295 aa)
LOC102737114Leucine-rich repeat-containing protein 31-like. (211 aa)
LOC102740611TNF receptor-associated factor. (490 aa)
APPAmyloid beta A4 protein. (753 aa)
IKBKBInhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (756 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (326 aa)
LRRC45Leucine-rich repeat-containing protein 45. (670 aa)
LOC102729256TNF receptor-associated factor 3-like. (283 aa)
CD180CD180 antigen. (661 aa)
PPP4R1Serine/threonine-protein phosphatase 4 regulatory subunit 1-like isoform X1. (367 aa)
NOD2Nucleotide-binding oligomerization domain-containing protein 2. (1013 aa)
LOC102730779Coiled-coil domain-containing protein 71L-like. (112 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2 isoform X2. (505 aa)
USP18Ubl carboxyl-terminal hydrolase 18; Belongs to the peptidase C19 family. (370 aa)
NLRP6NACHT, LRR and PYD domains-containing protein 6. (893 aa)
LOC102748381Inhibitor of nuclear factor kappa-B kinase subunit epsilon-like. (618 aa)
IRF7Interferon regulatory factor 7. (470 aa)
RPS6KA3Ribosomal protein S6 kinase. (740 aa)
LOC102739213High mobility group protein B1-like. (214 aa)
CHUKInhibitor of nuclear factor kappa-B kinase subunit alpha. (745 aa)
LOC102730470Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (394 aa)
LOC102728244Interleukin-1 receptor-associated kinase 1-like. (299 aa)
MAP3K1Mitogen-activated protein kinase kinase kinase 1. (1345 aa)
NLRX1NLR family member X1. (975 aa)
KHNYNProtein KHNYN. (668 aa)
JUNTranscription factor AP-1; Belongs to the bZIP family. (335 aa)
NFKBIBNF-kappa-B inhibitor beta isoform X2. (354 aa)
IKBKGNF-kappa-B essential modulator isoform X2. (419 aa)
DUSP6Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
BIRC7Baculoviral IAP repeat-containing protein 7. (287 aa)
LY96Lymphocyte antigen 96 isoform X1. (160 aa)
TICAM2TIR domain-containing adapter molecule 2. (238 aa)
NOD1Nucleotide-binding oligomerization domain-containing protein 1. (953 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (218 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (676 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa)
TNIP2TNFAIP3-interacting protein 2. (432 aa)
LOC102735971Ubiquitin-conjugating enzyme E2 N-like; Belongs to the ubiquitin-conjugating enzyme family. (199 aa)
LOC102750157Leucine-rich repeat-containing protein 31-like. (523 aa)
AGERAdvanced glycosylation end product-specific receptor. (397 aa)
PELI2E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (420 aa)
TANKTRAF family member-associated NF-kappa-B activator isoform X2. (426 aa)
UBE2NUbiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
ATF1Cyclic AMP-dependent transcription factor ATF-1 isoform X2. (270 aa)
TAB3TGF-beta-activated kinase 1 and MAP3K7-binding protein 3-like. (717 aa)
LOC102729636polyubiquitin-B-like. (77 aa)
MAP2K7Dual specificity mitogen-activated protein kinase kinase 7 isoform X1. (435 aa)
CREB1Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
LOC102750322polyubiquitin-B-like. (153 aa)
NFKB1Nuclear factor NF-kappa-B p105 subunit. (254 aa)
NFKBIANF-kappa-B inhibitor alpha isoform X2. (314 aa)
MAP2K6Dual specificity mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa)
TMEM189Transmembrane protein 189. (221 aa)
LOC102749246Ubiquitin-conjugating enzyme E2 variant 1-like isoform X2. (147 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (814 aa)
DUSP7Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (406 aa)
PPP2CBSerine/threonine-protein phosphatase. (308 aa)
KIAA1468lisH domain and HEAT repeat-containing protein KIAA1468 homolog isoform X1. (1214 aa)
SARM1Sterile alpha and TIR motif-containing protein 1. (724 aa)
LOC102728200ubiquitin-40S ribosomal protein S27a-like. (154 aa)
ECSITEvolutionarily conserved signaling intermediate in Toll pathway, mitochondrial. (409 aa)
MAPK10Mitogen-activated protein kinase. (464 aa)
LOC102749618Toll-like receptor 4-like; Belongs to the Toll-like receptor family. (793 aa)
ATF7Cyclic AMP-dependent transcription factor ATF-7 isoform X2. (483 aa)
IKBKEInhibitor of nuclear factor kappa-B kinase subunit epsilon. (106 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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