39 items (Leptonychotes weddellii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	IKBKE	Inhibitor of nuclear factor kappa-B kinase subunit epsilon. (106 aa)
	SIKE1	Suppressor of IKBKE 1 isoform X1. (211 aa)
	UBE2L6	ubiquitin/ISG15-conjugating enzyme E2 L6; Belongs to the ubiquitin-conjugating enzyme family. (153 aa)
	TOMM70A	Mitochondrial import receptor subunit TOM70. (609 aa)
	LOC102728200	ubiquitin-40S ribosomal protein S27a-like. (154 aa)
	NFKBIA	NF-kappa-B inhibitor alpha isoform X2. (314 aa)
	ISG15	Ubiquitin-like protein ISG15. (169 aa)
	NFKB1	Nuclear factor NF-kappa-B p105 subunit. (254 aa)
	LOC102750322	polyubiquitin-B-like. (153 aa)
	TAX1BP1	Tax1-binding protein 1 homolog isoform X1. (686 aa)
	RNF216	E3 ubiquitin-protein ligase RNF216 isoform X1. (928 aa)
	TNFAIP3	Tumor necrosis factor alpha-induced protein 3. (790 aa)
	AGER	Advanced glycosylation end product-specific receptor. (397 aa)
	OTUD5	OTU domain-containing protein 5 isoform X1. (376 aa)
	DHX58	Probable ATP-dependent RNA helicase DHX58 isoform X1. (678 aa)
	RNF135	E3 ubiquitin-protein ligase RNF135. (188 aa)
	IKBKG	NF-kappa-B essential modulator isoform X2. (419 aa)
	NFKBIB	NF-kappa-B inhibitor beta isoform X2. (354 aa)
	NLRX1	NLR family member X1. (975 aa)
	CHUK	Inhibitor of nuclear factor kappa-B kinase subunit alpha. (745 aa)
	LOC102739213	High mobility group protein B1-like. (214 aa)
	IRF7	Interferon regulatory factor 7. (470 aa)
	LOC102748381	Inhibitor of nuclear factor kappa-B kinase subunit epsilon-like. (618 aa)
	LOC102730779	Coiled-coil domain-containing protein 71L-like. (112 aa)
	MAVS	LOW QUALITY PROTEIN: mitochondrial antiviral-signaling protein. (522 aa)
	LOC102728857	Probable ATP-dependent RNA helicase DDX58-like. (294 aa)
	IKBKB	Inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (756 aa)
	APP	Amyloid beta A4 protein. (753 aa)
	NKIRAS2	NF-kappa-B inhibitor-interacting Ras-like protein 2 isoform X2. (191 aa)
	NKIRAS1	NF-kappa-B inhibitor-interacting Ras-like protein 1 isoform X1. (192 aa)
	KXD1	kxDL motif-containing protein 1 isoform X1. (176 aa)
	UBA52	ubiquitin-60S ribosomal protein L40 isoform X3. (128 aa)
	LOC102747337	ubiquitin-40S ribosomal protein S27a-like. (154 aa)
	S100A12	Protein S100; Belongs to the S-100 family. (92 aa)
	LOC102726367	Heat shock protein HSP 90-alpha-like. (262 aa)
	S100B	Protein S100; Belongs to the S-100 family. (92 aa)
	NFKB2	Nuclear factor NF-kappa-B p100 subunit. (900 aa)
	LOC102732364	Brorin-like. (133 aa)
	LOC102746862	ubiquitin-40S ribosomal protein S27a-like isoform X1. (156 aa)

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGER	APP	A0A2U3XY32	A0A2U3YJP2	Advanced glycosylation end product-specific receptor.	Amyloid beta A4 protein.	0.634
AGER	LOC102739213	A0A2U3XY32	A0A2U3YCB6	Advanced glycosylation end product-specific receptor.	High mobility group protein B1-like.	0.720
AGER	NFKB1	A0A2U3XY32	A0A2U3XMD9	Advanced glycosylation end product-specific receptor.	Nuclear factor NF-kappa-B p105 subunit.	0.434
AGER	S100A12	A0A2U3XY32	A0A2U3YX70	Advanced glycosylation end product-specific receptor.	Protein S100; Belongs to the S-100 family.	0.781
AGER	S100B	A0A2U3XY32	A0A2U3Z3M3	Advanced glycosylation end product-specific receptor.	Protein S100; Belongs to the S-100 family.	0.970
APP	AGER	A0A2U3YJP2	A0A2U3XY32	Amyloid beta A4 protein.	Advanced glycosylation end product-specific receptor.	0.634
APP	NFKB1	A0A2U3YJP2	A0A2U3XMD9	Amyloid beta A4 protein.	Nuclear factor NF-kappa-B p105 subunit.	0.521
APP	NFKB2	A0A2U3YJP2	A0A2U3Z5U0	Amyloid beta A4 protein.	Nuclear factor NF-kappa-B p100 subunit.	0.434
APP	S100B	A0A2U3YJP2	A0A2U3Z3M3	Amyloid beta A4 protein.	Protein S100; Belongs to the S-100 family.	0.514
CHUK	IKBKB	A0A2U3YBY3	A0A2U3YJI5	Inhibitor of nuclear factor kappa-B kinase subunit alpha.	Inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1.	0.999
CHUK	IKBKG	A0A2U3YBY3	A0A2U3Y6Q4	Inhibitor of nuclear factor kappa-B kinase subunit alpha.	NF-kappa-B essential modulator isoform X2.	0.999
CHUK	IRF7	A0A2U3YBY3	A0A2U3YDR6	Inhibitor of nuclear factor kappa-B kinase subunit alpha.	Interferon regulatory factor 7.	0.929
CHUK	LOC102726367	A0A2U3YBY3	A0A2U3YZ27	Inhibitor of nuclear factor kappa-B kinase subunit alpha.	Heat shock protein HSP 90-alpha-like.	0.629
CHUK	LOC102728200	A0A2U3YBY3	A0A2U3XJ47	Inhibitor of nuclear factor kappa-B kinase subunit alpha.	ubiquitin-40S ribosomal protein S27a-like.	0.535
CHUK	LOC102746862	A0A2U3YBY3	A0A2U3Z815	Inhibitor of nuclear factor kappa-B kinase subunit alpha.	ubiquitin-40S ribosomal protein S27a-like isoform X1.	0.535
CHUK	LOC102747337	A0A2U3YBY3	A0A2U3YWH0	Inhibitor of nuclear factor kappa-B kinase subunit alpha.	ubiquitin-40S ribosomal protein S27a-like.	0.535
CHUK	LOC102748381	A0A2U3YBY3	A0A2U3YDT3	Inhibitor of nuclear factor kappa-B kinase subunit alpha.	Inhibitor of nuclear factor kappa-B kinase subunit epsilon-like.	0.513
CHUK	LOC102750322	A0A2U3YBY3	A0A2U3XMJ2	Inhibitor of nuclear factor kappa-B kinase subunit alpha.	polyubiquitin-B-like.	0.596
CHUK	MAVS	A0A2U3YBY3	A0A2U3YG15	Inhibitor of nuclear factor kappa-B kinase subunit alpha.	LOW QUALITY PROTEIN: mitochondrial antiviral-signaling protein.	0.961
CHUK	NFKB1	A0A2U3YBY3	A0A2U3XMD9	Inhibitor of nuclear factor kappa-B kinase subunit alpha.	Nuclear factor NF-kappa-B p105 subunit.	0.980