STRINGSTRING
LOC102746703 LOC102746703 LOC102726804 LOC102726804 TAF1C TAF1C POLR2K POLR2K POLR2E POLR2E DNMT3B DNMT3B LOC102734854 LOC102734854 MYO1D MYO1D LOC102743898 LOC102743898 EZH1 EZH1 GSK3A GSK3A LOC102745013 LOC102745013 LOC102745317 LOC102745317 LOC102730819 LOC102730819 LOC102730207 LOC102730207 LOC102725568 LOC102725568 POLR1C POLR1C LOC102750824 LOC102750824 KAT2A KAT2A CD3EAP CD3EAP POLR2H POLR2H AEBP2 AEBP2 POLR1A POLR1A LOC102738587 LOC102738587 LOC102742396 LOC102742396 LOC102738290 LOC102738290 LOC102737083 LOC102737083 RBBP7 RBBP7 TBPL2 TBPL2 LOC102732990 LOC102732990 LOC102744967 LOC102744967 MYO1G MYO1G EED EED MYO1C MYO1C POLR2L POLR2L GSK3B GSK3B LOC102745380 LOC102745380 LOC102728431 LOC102728431 LOC102750817 LOC102750817 LOC102746084 LOC102746084 LOC102726286 LOC102726286 LOC102739804 LOC102739804 LOC102744317 LOC102744317 LOC102742187 LOC102742187 TET3 TET3 BAZ2B BAZ2B SMARCA5 SMARCA5 RBBP4 RBBP4 DNMT3A DNMT3A TAF1D TAF1D RRP8 RRP8 MBD2 MBD2 LOC102731039 LOC102731039 EZH2 EZH2 KAT2B KAT2B EP300 EP300 POLR1E POLR1E TET1 TET1 DDX21 DDX21 MTF2 MTF2 ERCC6 ERCC6 DEK DEK SMARCA1 SMARCA1 LOC102750992 LOC102750992 ZNRD1 ZNRD1 JARID2 JARID2 POLR2F POLR2F LOC102731009 LOC102731009 SAP130 SAP130 MYBBP1A MYBBP1A TET2 TET2 TAF1A TAF1A BAZ1B BAZ1B TBP TBP LOC102735996 LOC102735996 LOC102741823 LOC102741823 LOC102732330 LOC102732330 DNMT1 DNMT1 LOC102747225 LOC102747225
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
LOC102746703Unconventional myosin-Ia-like; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (619 aa)
LOC102726804Histone H2B; Belongs to the histone H2B family. (126 aa)
TAF1CTATA box-binding protein-associated factor RNA polymerase I subunit C. (849 aa)
POLR2KDNA-directed RNA polymerases I, II, and III subunit RPABC4. (58 aa)
POLR2EDNA-directed RNA polymerases I, II, and III subunit RPABC1 isoform X1. (210 aa)
DNMT3BDNA (Cytosine-5)-methyltransferase 3B isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (856 aa)
LOC102734854Splicing factor 3B subunit 1-like. (1024 aa)
MYO1DUnconventional myosin-Id-like; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (313 aa)
LOC102743898Histone H2B type W-T-like; Belongs to the histone H2B family. (174 aa)
EZH1Histone-lysine N-methyltransferase EZH1. (209 aa)
GSK3AGlycogen synthase kinase-3 alpha; Belongs to the protein kinase superfamily. (419 aa)
LOC102745013Histone H3; Belongs to the histone H3 family. (136 aa)
LOC102745317Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC102730819Histone H3; Belongs to the histone H3 family. (136 aa)
LOC102730207Histone H2A; Belongs to the histone H2A family. (143 aa)
LOC102725568Histone H2B; Belongs to the histone H2B family. (127 aa)
POLR1CDNA-directed RNA polymerases I and III subunit RPAC1. (346 aa)
LOC102750824Histone-lysine N-methyltransferase EZH1-like. (522 aa)
KAT2AHistone acetyltransferase KAT2A isoform X2. (838 aa)
CD3EAPDNA-directed RNA polymerase I subunit RPA34. (522 aa)
POLR2HDNA-directed RNA polymerases I, II, and III subunit RPABC3 isoform X1. (114 aa)
AEBP2Zinc finger protein AEBP2 isoform X1. (513 aa)
POLR1ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1712 aa)
LOC102738587Histone H2B subacrosomal variant-like; Belongs to the histone H2B family. (122 aa)
LOC102742396DNA-directed RNA polymerase I subunit RPA2-like. (304 aa)
LOC102738290Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC102737083Histone H3; Belongs to the histone H3 family. (136 aa)
RBBP7Histone-binding protein RBBP7 isoform X1. (469 aa)
TBPL2TATA box-binding protein-like protein 2. (344 aa)
LOC102732990Histone H2A; Belongs to the histone H2A family. (140 aa)
LOC102744967Histone deacetylase complex subunit SAP130-like. (673 aa)
MYO1GUnconventional myosin-Ig isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1013 aa)
EEDPolycomb protein EED isoform X1. (466 aa)
MYO1CUnconventional myosin-Ic isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1063 aa)
POLR2LDNA-directed RNA polymerases I, II, and III subunit RPABC5. (67 aa)
GSK3BGlycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa)
LOC102745380Histone-lysine N-methyltransferase EZH2-like. (556 aa)
LOC102728431Histone H2B; Belongs to the histone H2B family. (119 aa)
LOC102750817Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC102746084Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
LOC102726286Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (78 aa)
LOC102739804Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC102744317Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC102742187Histone H2B; Belongs to the histone H2B family. (126 aa)
TET3Methylcytosine dioxygenase TET3. (1774 aa)
BAZ2BBromodomain adjacent to zinc finger domain protein 2B isoform X1. (2170 aa)
SMARCA5SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5. (1052 aa)
RBBP4Histone-binding protein RBBP4. (380 aa)
DNMT3ADNA (Cytosine-5)-methyltransferase 3A; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (835 aa)
TAF1DTATA box-binding protein-associated factor RNA polymerase I subunit D. (272 aa)
RRP8Ribosomal RNA-processing protein 8; Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone- modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and pr [...] (457 aa)
MBD2methyl-CpG-binding domain protein 2. (212 aa)
LOC102731039Histone H3.3-like. (128 aa)
EZH2Histone-lysine N-methyltransferase EZH2. (144 aa)
KAT2BHistone acetyltransferase KAT2B. (735 aa)
EP300Histone acetyltransferase p300. (2425 aa)
POLR1EDNA-directed RNA polymerase I subunit RPA49 isoform X1. (419 aa)
TET1Methylcytosine dioxygenase TET1. (2136 aa)
DDX21Nucleolar RNA helicase 2 isoform X1. (795 aa)
MTF2Metal-response element-binding transcription factor 2 isoform X1. (593 aa)
ERCC6DNA excision repair protein ERCC-6. (457 aa)
DEKProtein DEK. (314 aa)
SMARCA1Probable global transcription activator SNF2L1 isoform X1. (1067 aa)
LOC102750992Histone H2B; Belongs to the histone H2B family. (127 aa)
ZNRD1DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (123 aa)
JARID2Protein Jumonji. (1075 aa)
POLR2FDNA-directed RNA polymerases I, II, and III subunit RPABC2. (127 aa)
LOC102731009DNA-directed RNA polymerase I subunit RPA43-like. (116 aa)
SAP130Histone deacetylase complex subunit SAP130-like. (324 aa)
MYBBP1AMyb-binding protein 1A isoform X1. (1332 aa)
TET2Methylcytosine dioxygenase TET2 isoform X2. (2016 aa)
TAF1ATATA box-binding protein-associated factor RNA polymerase I subunit A. (450 aa)
BAZ1BTyrosine-protein kinase BAZ1B. (1443 aa)
TBPTATA-box-binding protein. (322 aa)
LOC102735996Unconventional myosin-Id-like. (120 aa)
LOC102741823DNA-directed RNA polymerase I subunit RPA2-like. (293 aa)
LOC102732330Histone H3; Belongs to the histone H3 family. (136 aa)
DNMT1DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1613 aa)
LOC102747225DNA-directed RNA polymerase I subunit RPA43-like. (316 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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