STRINGSTRING
KIF21A KIF21A KIF19 KIF19 CTSS CTSS KIF2B KIF2B KIF2C KIF2C KLC4 KLC4 FAM193A FAM193A LOC102746878 LOC102746878 LOC102741082 LOC102741082 LOC102740784 LOC102740784 APPBP2 APPBP2 AP1M1 AP1M1 AP1S2 AP1S2 TTC19 TTC19 KIF18B KIF18B CAPZA2 CAPZA2 SH3GL2 SH3GL2 CTSB CTSB MIEF1 MIEF1 SEC23A SEC23A CAPZA3 CAPZA3 LOC102736746 LOC102736746 KIF18A KIF18A DCTN5 DCTN5 SEC23B SEC23B SEC24A SEC24A SAR1B SAR1B ACTR1A ACTR1A KIF2A KIF2A DYNC1I2 DYNC1I2 DYNC1LI2 DYNC1LI2 CAPZB CAPZB KIF3C KIF3C AP1S1 AP1S1 ACTR1B ACTR1B KIF11 KIF11 LOC102732471 LOC102732471 LOC102725609 LOC102725609 LOC102726107 LOC102726107 TUBAL3 TUBAL3 KIF3A KIF3A CST11 CST11 TUBA4A TUBA4A LOC102738506 LOC102738506 CST8 CST8 LOC102736798 LOC102736798 LOC102737106 LOC102737106 TUBB1 TUBB1 RAB7A RAB7A AP1G1 AP1G1 FNDC7 FNDC7 KIF15 KIF15 CTSE CTSE AP2A2 AP2A2 DCTN4 DCTN4 CD74 CD74 KIF3B KIF3B AP1M2 AP1M2 DYNC1LI1 DYNC1LI1 CLTC CLTC KIFAP3 KIFAP3 KLC2 KLC2 DCTN2 DCTN2 CANX CANX LOC102727326 LOC102727326 AP2M1 AP2M1 LOC102750166 LOC102750166 LOC102750454 LOC102750454 LOC102748462 LOC102748462 LOC102747485 LOC102747485 KIF22 KIF22 LAG3 LAG3 KIF13B KIF13B DNM3 DNM3 KIF4A KIF4A TUBB4B TUBB4B KIF9 KIF9 KIF20A KIF20A LOC102735475 LOC102735475 LOC102735177 LOC102735177 LOC102734471 LOC102734471 CTSA CTSA LOC102736866 LOC102736866 CTSD CTSD LOC102738067 LOC102738067 SEC31B SEC31B TUBB3 TUBB3 LOC102727401 LOC102727401 LOC102734456 LOC102734456 KIF28P KIF28P SAR1A SAR1A LOC102743884 LOC102743884 LOC102735638 LOC102735638 LOC102744490 LOC102744490 KLC1 KLC1 LOC102726454 LOC102726454 LOC102738640 LOC102738640 FAM166B FAM166B TUBE1 TUBE1 LOC102732933 LOC102732933 KIF1B KIF1B KIF1A KIF1A LOC102749901 LOC102749901 AP2S1 AP2S1 KIF26B KIF26B CTSH CTSH KIFC3 KIFC3 CPVL CPVL DYNLL1 DYNLL1 LOC102739419 LOC102739419 AP2A1 AP2A1 KIF27 KIF27 DNM1 DNM1 ACTRT3 ACTRT3 ACTR10 ACTR10 CLTA CLTA ARF1 ARF1 KIF1C KIF1C LOC102731290 LOC102731290 SEC24B SEC24B CTSO CTSO
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KIF21AKinesin-like protein KIF21A isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1673 aa)
KIF19Kinesin-like protein KIF19; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1001 aa)
CTSSCathepsin S isoform X1; Belongs to the peptidase C1 family. (340 aa)
KIF2BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (683 aa)
KIF2CKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (723 aa)
KLC4Kinesin light chain 4 isoform X1. (634 aa)
FAM193AProtein FAM193A. (1418 aa)
LOC102746878Cytoplasmic dynein 1 intermediate chain 1-like. (158 aa)
LOC102741082DLA class II histocompatibility antigen, DR-1 beta chain-like. (266 aa)
LOC102740784HLA class II histocompatibility antigen, DR alpha chain-like; Belongs to the MHC class II family. (254 aa)
APPBP2Amyloid protein-binding protein 2. (498 aa)
AP1M1AP-1 complex subunit mu-1 isoform X1; Belongs to the adaptor complexes medium subunit family. (435 aa)
AP1S2AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (157 aa)
TTC19Tetratricopeptide repeat protein 19, mitochondrial. (268 aa)
KIF18BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (866 aa)
CAPZA2F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (286 aa)
SH3GL2endophilin-A1. (352 aa)
CTSBCathepsin B; Belongs to the peptidase C1 family. (339 aa)
MIEF1Mitochondrial dynamics protein MID51. (463 aa)
SEC23AProtein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (639 aa)
CAPZA3F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (299 aa)
LOC102736746Cytoplasmic dynein 1 intermediate chain 1-like. (396 aa)
KIF18AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (898 aa)
DCTN5Dynactin subunit 5. (182 aa)
SEC23BProtein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (767 aa)
SEC24AProtein transport protein Sec24A. (1100 aa)
SAR1BGTP-binding protein SAR1b; Belongs to the small GTPase superfamily. SAR1 family. (198 aa)
ACTR1AAlpha-centractin isoform X1. (376 aa)
KIF2AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (744 aa)
DYNC1I2Cytoplasmic dynein 1 intermediate chain 2 isoform X1. (638 aa)
DYNC1LI2Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (472 aa)
CAPZBF-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (185 aa)
KIF3CKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (790 aa)
AP1S1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (158 aa)
ACTR1BBeta-centractin isoform X1. (376 aa)
KIF11Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (923 aa)
LOC102732471Tubulin alpha-1B chain-like. (134 aa)
LOC102725609Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
LOC102726107Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
TUBAL3Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (398 aa)
KIF3AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (726 aa)
CST11Cystatin-11. (137 aa)
TUBA4ATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa)
LOC102738506Cystatin-9-like. (136 aa)
CST8Cystatin-8. (142 aa)
LOC102736798Cystatin-9-like. (155 aa)
LOC102737106Cystatin-13-like isoform X1. (141 aa)
TUBB1Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (457 aa)
RAB7ARas-related protein Rab-7a isoform X1. (207 aa)
AP1G1AP-1 complex subunit gamma. (825 aa)
FNDC7Fibronectin type III domain-containing protein 7. (740 aa)
KIF15Kinesin-like protein KIF15 isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1388 aa)
CTSECathepsin E isoform X1; Belongs to the peptidase A1 family. (396 aa)
AP2A2AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (936 aa)
DCTN4Dynactin subunit 4 isoform X2. (467 aa)
CD74HLA class II histocompatibility antigen gamma chain. (279 aa)
KIF3BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (747 aa)
AP1M2AP-1 complex subunit mu-2 isoform X1; Belongs to the adaptor complexes medium subunit family. (425 aa)
DYNC1LI1Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (524 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1675 aa)
KIFAP3Kinesin-associated protein 3. (748 aa)
KLC2Kinesin light chain 2 isoform X1. (622 aa)
DCTN2Dynactin subunit 2 isoform X2. (405 aa)
CANXCalnexin isoform X1. (594 aa)
LOC102727326Cathepsin L1-like isoform X1; Belongs to the peptidase C1 family. (334 aa)
AP2M1AP-2 complex subunit mu. (189 aa)
LOC102750166HLA class II histocompatibility antigen, DM beta chain-like. (263 aa)
LOC102750454HLA class II histocompatibility antigen, DM alpha chain-like; Belongs to the MHC class II family. (261 aa)
LOC102748462HLA class II histocompatibility antigen, DO beta chain-like. (273 aa)
LOC102747485HLA class II histocompatibility antigen, DQ beta 2 chain-like isoform X2. (329 aa)
KIF22Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (660 aa)
LAG3Lymphocyte activation gene 3 protein. (389 aa)
KIF13BKinesin-like protein KIF13B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1942 aa)
DNM3Dynamin-3 isoform X2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (865 aa)
KIF4AChromosome-associated kinesin KIF4A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (985 aa)
TUBB4BTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
KIF9Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (789 aa)
KIF20AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (889 aa)
LOC102735475Myelin transcription factor 1-like protein-like. (644 aa)
LOC102735177Myelin transcription factor 1-like protein-like. (184 aa)
LOC102734471Dynactin subunit 1-like. (1117 aa)
CTSACarboxypeptidase; Belongs to the peptidase S10 family. (495 aa)
LOC102736866Cytoplasmic dynein 1 heavy chain 1-like. (856 aa)
CTSDCathepsin D; Belongs to the peptidase A1 family. (410 aa)
LOC102738067Protein transport protein Sec31B-like. (624 aa)
SEC31BProtein transport protein Sec31B-like. (585 aa)
TUBB3Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (378 aa)
LOC102727401Dynactin subunit 3-like. (96 aa)
LOC102734456HLA class II histocompatibility antigen, DO alpha chain-like; Belongs to the MHC class II family. (250 aa)
KIF28PKinesin-like protein KIF28P. (452 aa)
SAR1AGTP-binding protein SAR1a; Belongs to the small GTPase superfamily. SAR1 family. (198 aa)
LOC102743884Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
LOC102735638Protein transport protein Sec24D-like. (565 aa)
LOC102744490Kinesin-like protein KIF1C-like; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1153 aa)
KLC1Kinesin light chain 1. (554 aa)
LOC102726454Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (264 aa)
LOC102738640AP complex subunit beta. (683 aa)
FAM166BProtein FAM166B. (278 aa)
TUBE1Tubulin epsilon chain; Belongs to the tubulin family. (475 aa)
LOC102732933Dynactin subunit 6-like. (127 aa)
KIF1BKinesin-like protein KIF1B. (593 aa)
KIF1AKinesin-like protein KIF1A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1785 aa)
LOC102749901Gamma-interferon-inducible-lysosomal thiol reductase-like. (252 aa)
AP2S1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (142 aa)
KIF26BKinesin-like protein KIF26B-like; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (700 aa)
CTSHPro-cathepsin H; Belongs to the peptidase C1 family. (331 aa)
KIFC3Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (831 aa)
CPVLProbable serine carboxypeptidase CPVL-like; Belongs to the peptidase S10 family. (477 aa)
DYNLL1Dynein light chain. (89 aa)
LOC102739419Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
AP2A1AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (978 aa)
KIF27Kinesin-like protein KIF27; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1346 aa)
DNM1Dynamin-1 isoform X2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (864 aa)
ACTRT3Actin-related protein T3; Belongs to the actin family. (372 aa)
ACTR10Actin-related protein 10; Belongs to the actin family. (417 aa)
CLTAClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (171 aa)
ARF1ADP-ribosylation factor 1; Belongs to the small GTPase superfamily. Arf family. (181 aa)
KIF1CKinesin-like protein KIF1C; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1104 aa)
LOC102731290Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
SEC24BProtein transport protein Sec24B isoform X1. (1258 aa)
CTSOCathepsin O; Belongs to the peptidase C1 family. (321 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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