(23 nodes) SUMOylation of transcription factors network (Leptonychotes weddellii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC102740606	SUMO-conjugating enzyme UBC9-like; Belongs to the ubiquitin-conjugating enzyme family. (123 aa)
	HIC2	Hypermethylated in cancer 2 protein-like. (616 aa)
	FOXD4L3	Forkhead box protein D4-like 3. (303 aa)
	SUMO3	Small ubiquitin-related modifier. (111 aa)
	SP3	Transcription factor Sp3-like. (751 aa)
	PIAS1	E3 SUMO-protein ligase PIAS1 isoform X1. (653 aa)
	SP4	Transcription factor Sp4-like. (562 aa)
	LOC102749849	Microphthalmia-associated transcription factor-like. (181 aa)
	SUMO2	Small ubiquitin-related modifier. (95 aa)
	KCTD2	BTB/POZ domain-containing protein KCTD2. (221 aa)
	TFEB	Transcription factor EB. (329 aa)
	PIAS3	E3 SUMO-protein ligase PIAS3. (628 aa)
	SP5	Transcription factor Sp5. (310 aa)
	FOXL2	Forkhead box protein L2. (257 aa)
	SUMO1	Small ubiquitin-related modifier. (101 aa)
	ZMIZ1	Zinc finger MIZ domain-containing protein 1. (957 aa)
	ZMIZ2	Zinc finger MIZ domain-containing protein 2 isoform X1. (919 aa)
	FOXD2	Forkhead box protein D2. (448 aa)
	TFE3	Transcription factor E3 isoform X1. (571 aa)
	PIAS4	E3 SUMO-protein ligase PIAS4. (503 aa)
	LOC102737595	Small ubiquitin-related modifier. (95 aa)
	HIC1	Hypermethylated in cancer 1 protein. (560 aa)
	FOXD3	Forkhead box protein D3. (357 aa)

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KCTD2	LOC102737595	A0A2U3X9R0	A0A2U3Y8B4	BTB/POZ domain-containing protein KCTD2.	Small ubiquitin-related modifier.	0.842
KCTD2	PIAS1	A0A2U3X9R0	A0A2U3Z0G3	BTB/POZ domain-containing protein KCTD2.	E3 SUMO-protein ligase PIAS1 isoform X1.	0.773
KCTD2	PIAS3	A0A2U3X9R0	A0A2U3XFU1	BTB/POZ domain-containing protein KCTD2.	E3 SUMO-protein ligase PIAS3.	0.773
KCTD2	PIAS4	A0A2U3X9R0	A0A2U3Y4Z2	BTB/POZ domain-containing protein KCTD2.	E3 SUMO-protein ligase PIAS4.	0.773
KCTD2	SUMO1	A0A2U3X9R0	A0A2U3XT97	BTB/POZ domain-containing protein KCTD2.	Small ubiquitin-related modifier.	0.949
KCTD2	SUMO2	A0A2U3X9R0	A0A2U3X9G7	BTB/POZ domain-containing protein KCTD2.	Small ubiquitin-related modifier.	0.842
KCTD2	SUMO3	A0A2U3X9R0	A0A2U3YTI9	BTB/POZ domain-containing protein KCTD2.	Small ubiquitin-related modifier.	0.842
KCTD2	ZMIZ1	A0A2U3X9R0	A0A2U3XU99	BTB/POZ domain-containing protein KCTD2.	Zinc finger MIZ domain-containing protein 1.	0.720
KCTD2	ZMIZ2	A0A2U3X9R0	A0A2U3XYD9	BTB/POZ domain-containing protein KCTD2.	Zinc finger MIZ domain-containing protein 2 isoform X1.	0.720
LOC102737595	KCTD2	A0A2U3Y8B4	A0A2U3X9R0	Small ubiquitin-related modifier.	BTB/POZ domain-containing protein KCTD2.	0.842
LOC102737595	LOC102740606	A0A2U3Y8B4	A0A2U3YE51	Small ubiquitin-related modifier.	SUMO-conjugating enzyme UBC9-like; Belongs to the ubiquitin-conjugating enzyme family.	0.972
LOC102737595	PIAS1	A0A2U3Y8B4	A0A2U3Z0G3	Small ubiquitin-related modifier.	E3 SUMO-protein ligase PIAS1 isoform X1.	0.841
LOC102737595	PIAS3	A0A2U3Y8B4	A0A2U3XFU1	Small ubiquitin-related modifier.	E3 SUMO-protein ligase PIAS3.	0.790
LOC102737595	PIAS4	A0A2U3Y8B4	A0A2U3Y4Z2	Small ubiquitin-related modifier.	E3 SUMO-protein ligase PIAS4.	0.953
LOC102737595	SUMO1	A0A2U3Y8B4	A0A2U3XT97	Small ubiquitin-related modifier.	Small ubiquitin-related modifier.	0.914
LOC102737595	ZMIZ1	A0A2U3Y8B4	A0A2U3XU99	Small ubiquitin-related modifier.	Zinc finger MIZ domain-containing protein 1.	0.576
LOC102737595	ZMIZ2	A0A2U3Y8B4	A0A2U3XYD9	Small ubiquitin-related modifier.	Zinc finger MIZ domain-containing protein 2 isoform X1.	0.576
LOC102740606	LOC102737595	A0A2U3YE51	A0A2U3Y8B4	SUMO-conjugating enzyme UBC9-like; Belongs to the ubiquitin-conjugating enzyme family.	Small ubiquitin-related modifier.	0.972
LOC102740606	LOC102749849	A0A2U3YE51	A0A2U3Z7J0	SUMO-conjugating enzyme UBC9-like; Belongs to the ubiquitin-conjugating enzyme family.	Microphthalmia-associated transcription factor-like.	0.425
LOC102740606	PIAS1	A0A2U3YE51	A0A2U3Z0G3	SUMO-conjugating enzyme UBC9-like; Belongs to the ubiquitin-conjugating enzyme family.	E3 SUMO-protein ligase PIAS1 isoform X1.	0.914