STRINGSTRING
LOC102732367 LOC102732367 LOC102735156 LOC102735156 LOC102736765 LOC102736765 LOC102746862 LOC102746862 NLRP9 NLRP9 NKIRAS1 NKIRAS1 PSMA8 PSMA8 IL18BP IL18BP PSMF1 PSMF1 TONSL TONSL PSMB5 PSMB5 PSMB11 PSMB11 PSMD9 PSMD9 PTPN5 PTPN5 MAP3K2 MAP3K2 KXD1 KXD1 UBA52 UBA52 LOC102729589 LOC102729589 LOC102733426 LOC102733426 LOC102746732 LOC102746732 LOC102747337 LOC102747337 NLRP13 NLRP13 LOC102735127 LOC102735127 LOC102749524 LOC102749524 GZMB GZMB S100A12 S100A12 PSMA4 PSMA4 LRRC71 LRRC71 LOC102730919 LOC102730919 IL1RN IL1RN PELI3 PELI3 IL1F10 IL1F10 PSMD10 PSMD10 CASP8 CASP8 LOC102734343 LOC102734343 PSMA5 PSMA5 LOC102730318 LOC102730318 MYD88 MYD88 LOC102726381 LOC102726381 S100B S100B STAT3 STAT3 PSMD6 PSMD6 NFKB2 NFKB2 LOC102732364 LOC102732364 LOC102729219 LOC102729219 PSMD4 PSMD4 PSMB4 PSMB4 RBX1 RBX1 PSMB10 PSMB10 IRAK4 IRAK4 CUL1 CUL1 SKP1 SKP1 LOC102728200 LOC102728200 LOC102749246 LOC102749246 PSMC2 PSMC2 MAP2K6 MAP2K6 NFKBIA NFKBIA PSMA6 PSMA6 NFKB1 NFKB1 LOC102742178 LOC102742178 LOC102750322 LOC102750322 PSMB2 PSMB2 PTPN23 PTPN23 USP14 USP14 IL18 IL18 LOC102734657 LOC102734657 LOC102729636 LOC102729636 TAB3 TAB3 IL13 IL13 UBE2N UBE2N PSMC6 PSMC6 PSMD14 PSMD14 PELI2 PELI2 AGER AGER LOC102750157 LOC102750157 LOC102735971 LOC102735971 TNIP2 TNIP2 TRAF6 TRAF6 IL18R1 IL18R1 IL18RAP IL18RAP IL1R2 IL1R2 PSMC5 PSMC5 PSMB8 PSMB8 LOC102733981 LOC102733981 LOC102745161 LOC102745161 PSME1 PSME1 PSME2 PSME2 PSME3 PSME3 IKBKG IKBKG PSMD8 PSMD8 NFKBIB NFKBIB KHNYN KHNYN CTSG CTSG NLRX1 NLRX1 LOC102728244 LOC102728244 MAP3K3 MAP3K3 CHUK CHUK LOC102739213 LOC102739213 NLRP6 NLRP6 USP18 USP18 LOC102730779 LOC102730779 PTPN21 PTPN21 LOC102749969 LOC102749969 PSMD7 PSMD7 PSMB6 PSMB6 LRRC45 LRRC45 IKBKB IKBKB APP APP LOC102737114 LOC102737114 PSMA3 PSMA3 NKIRAS2 NKIRAS2 LOC102728967 LOC102728967 PTPN9 PTPN9 PSMD11 PSMD11 LOC102743429 LOC102743429 PSMA7 PSMA7 IL1B IL1B LOC102739627 LOC102739627 LRRC14 LRRC14 LOC102750659 LOC102750659 IL1A IL1A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC102732367Proteasome subunit beta type-1-like. (140 aa)
LOC102735156Proteasome subunit beta type-5-like. (119 aa)
LOC102736765Interleukin-1 receptor-associated kinase 3-like. (125 aa)
LOC102746862ubiquitin-40S ribosomal protein S27a-like isoform X1. (156 aa)
NLRP9LOW QUALITY PROTEIN: NLR family, pyrin domain containing 9. (667 aa)
NKIRAS1NF-kappa-B inhibitor-interacting Ras-like protein 1 isoform X1. (192 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
IL18BPInterleukin-18-binding protein. (188 aa)
PSMF1Proteasome inhibitor PI31 subunit. (128 aa)
TONSLTonsoku-like protein. (879 aa)
PSMB5Proteasome subunit beta type-5. (160 aa)
PSMB11Proteasome subunit beta. (285 aa)
PSMD926S proteasome non-ATPase regulatory subunit 9 isoform X1. (223 aa)
PTPN5Tyrosine-protein phosphatase non-receptor type 5 isoform X1. (539 aa)
MAP3K2Mitogen-activated protein kinase kinase kinase 2. (540 aa)
KXD1kxDL motif-containing protein 1 isoform X1. (176 aa)
UBA52ubiquitin-60S ribosomal protein L40 isoform X3. (128 aa)
LOC102729589Tyrosine-protein phosphatase non-receptor type 20-like isoform X2. (179 aa)
LOC102733426Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (890 aa)
LOC102746732Ubiquitin-conjugating enzyme E2 N-like; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
LOC102747337ubiquitin-40S ribosomal protein S27a-like. (154 aa)
NLRP13NACHT, LRR and PYD domains-containing protein 13. (991 aa)
LOC10273512726S protease regulatory subunit 4-like isoform X1; Belongs to the AAA ATPase family. (440 aa)
LOC102749524LOW QUALITY PROTEIN: duodenase-1-like; Belongs to the peptidase S1 family. (251 aa)
GZMBGranzyme B; Belongs to the peptidase S1 family. (259 aa)
S100A12Protein S100; Belongs to the S-100 family. (92 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
LRRC71Leucine-rich repeat-containing protein 71. (559 aa)
LOC102730919Interleukin-1. (150 aa)
IL1RNInterleukin-1. (176 aa)
PELI3E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (468 aa)
IL1F10Interleukin-1. (152 aa)
PSMD1026S proteasome non-ATPase regulatory subunit 10 isoform X1. (226 aa)
CASP8Caspase-8 isoform X1; Belongs to the peptidase C14A family. (486 aa)
LOC102734343Single Ig IL-1-related receptor-like. (229 aa)
PSMA5Proteasome subunit alpha type. (235 aa)
LOC102730318Mothers against decapentaplegic homolog. (415 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa)
LOC10272638126S proteasome non-ATPase regulatory subunit 1-like. (574 aa)
S100BProtein S100; Belongs to the S-100 family. (92 aa)
STAT3Signal transducer and activator of transcription 3-like. (424 aa)
PSMD626S proteasome non-ATPase regulatory subunit 6 isoform X1. (389 aa)
NFKB2Nuclear factor NF-kappa-B p100 subunit. (900 aa)
LOC102732364Brorin-like. (133 aa)
LOC10272921926S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (778 aa)
PSMD426S proteasome non-ATPase regulatory subunit 4. (377 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
RBX1E3 ubiquitin-protein ligase RBX1 isoform X3. (108 aa)
PSMB10Proteasome subunit beta. (273 aa)
IRAK4Interleukin-1 receptor-associated kinase 4 isoform X1. (459 aa)
CUL1Cullin-1; Belongs to the cullin family. (327 aa)
SKP1S-phase kinase-associated protein 1 isoform X1; Belongs to the SKP1 family. (163 aa)
LOC102728200ubiquitin-40S ribosomal protein S27a-like. (154 aa)
LOC102749246Ubiquitin-conjugating enzyme E2 variant 1-like isoform X2. (147 aa)
PSMC226S protease regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa)
MAP2K6Dual specificity mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa)
NFKBIANF-kappa-B inhibitor alpha isoform X2. (314 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
NFKB1Nuclear factor NF-kappa-B p105 subunit. (254 aa)
LOC102742178Proteasome subunit alpha type. (234 aa)
LOC102750322polyubiquitin-B-like. (153 aa)
PSMB2Proteasome subunit beta. (201 aa)
PTPN23Tyrosine-protein phosphatase non-receptor type 23 isoform X1. (1558 aa)
USP14Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (494 aa)
IL18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa)
LOC10273465726S proteasome non-ATPase regulatory subunit 1-like. (279 aa)
LOC102729636polyubiquitin-B-like. (77 aa)
TAB3TGF-beta-activated kinase 1 and MAP3K7-binding protein 3-like. (717 aa)
IL13Interleukin-13. (133 aa)
UBE2NUbiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
PSMC626S protease regulatory subunit 10B. (291 aa)
PSMD1426S proteasome non-ATPase regulatory subunit 14. (310 aa)
PELI2E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (420 aa)
AGERAdvanced glycosylation end product-specific receptor. (397 aa)
LOC102750157Leucine-rich repeat-containing protein 31-like. (523 aa)
LOC102735971Ubiquitin-conjugating enzyme E2 N-like; Belongs to the ubiquitin-conjugating enzyme family. (199 aa)
TNIP2TNFAIP3-interacting protein 2. (432 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa)
IL18R1Interleukin-18 receptor 1. (540 aa)
IL18RAPInterleukin-18 receptor accessory protein. (593 aa)
IL1R2Interleukin-1 receptor type 2. (414 aa)
PSMC526S protease regulatory subunit 8; Belongs to the AAA ATPase family. (406 aa)
PSMB8Proteasome subunit beta. (276 aa)
LOC10273398126S proteasome non-ATPase regulatory subunit 2-like. (125 aa)
LOC102745161Signal transducer and activator of transcription 3-like. (301 aa)
PSME1Proteasome activator complex subunit 1 isoform X1. (249 aa)
PSME2Proteasome activator complex subunit 2 isoform X1. (239 aa)
PSME3Proteasome activator complex subunit 3 isoform X3. (254 aa)
IKBKGNF-kappa-B essential modulator isoform X2. (419 aa)
PSMD8LOW QUALITY PROTEIN: 26S proteasome non-ATPase regulatory subunit 8. (351 aa)
NFKBIBNF-kappa-B inhibitor beta isoform X2. (354 aa)
KHNYNProtein KHNYN. (668 aa)
CTSGCathepsin G; Belongs to the peptidase S1 family. (251 aa)
NLRX1NLR family member X1. (975 aa)
LOC102728244Interleukin-1 receptor-associated kinase 1-like. (299 aa)
MAP3K3Mitogen-activated protein kinase kinase kinase 3. (600 aa)
CHUKInhibitor of nuclear factor kappa-B kinase subunit alpha. (745 aa)
LOC102739213High mobility group protein B1-like. (214 aa)
NLRP6NACHT, LRR and PYD domains-containing protein 6. (893 aa)
USP18Ubl carboxyl-terminal hydrolase 18; Belongs to the peptidase C19 family. (370 aa)
LOC102730779Coiled-coil domain-containing protein 71L-like. (112 aa)
PTPN21Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (1157 aa)
LOC102749969Interleukin-33-like. (267 aa)
PSMD726S proteasome non-ATPase regulatory subunit 7-like. (324 aa)
PSMB6Proteasome subunit beta. (239 aa)
LRRC45Leucine-rich repeat-containing protein 45. (670 aa)
IKBKBInhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (756 aa)
APPAmyloid beta A4 protein. (753 aa)
LOC102737114Leucine-rich repeat-containing protein 31-like. (211 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
NKIRAS2NF-kappa-B inhibitor-interacting Ras-like protein 2 isoform X2. (191 aa)
LOC102728967Interleukin-1 receptor accessory protein-like 1-like. (418 aa)
PTPN9Tyrosine-protein phosphatase non-receptor type 9. (593 aa)
PSMD1126S proteasome non-ATPase regulatory subunit 11. (422 aa)
LOC102743429Leucine-rich repeat-containing protein LOC400891-like. (392 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (270 aa)
LOC102739627Interleukin-1. (155 aa)
LRRC14Leucine-rich repeat-containing protein 14. (503 aa)
LOC102750659Tonsoku-like protein-like. (490 aa)
IL1AInterleukin-1; Belongs to the IL-1 family. (265 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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