STRINGSTRING
SYVN1 SYVN1 LOC102730851 LOC102730851 LOC102746862 LOC102746862 LOC102741471 LOC102741471 LOC102735156 LOC102735156 LOC102731038 LOC102731038 LOC102732367 LOC102732367 SHH SHH LOC102729219 LOC102729219 PRKACA PRKACA PSMD6 PSMD6 NUMBL NUMBL LOC102726381 LOC102726381 GSK3A GSK3A LOC102744495 LOC102744495 LOC102734751 LOC102734751 PSMA5 PSMA5 PSMD10 PSMD10 MKS1 MKS1 LOC102750402 LOC102750402 PSMA4 PSMA4 LOC102735127 LOC102735127 LOC102747337 LOC102747337 HHATL HHATL IFT57 IFT57 UBA52 UBA52 KXD1 KXD1 ULK3 ULK3 SPOP SPOP PSMD9 PSMD9 PSMB11 PSMB11 PSMB5 PSMB5 PSMF1 PSMF1 LOC102746012 LOC102746012 PSMA8 PSMA8 LOC102751154 LOC102751154 LOC102736400 LOC102736400 THAP7 THAP7 PSMA7 PSMA7 ADCY9 ADCY9 PSMD11 PSMD11 FUZ FUZ PSMA3 PSMA3 HHIP HHIP ADRBK1 ADRBK1 LOC102749886 LOC102749886 PSMB6 PSMB6 P4HB P4HB LOC102735500 LOC102735500 PSMD7 PSMD7 DISP2 DISP2 TUB TUB GSK3B GSK3B LOC102739114 LOC102739114 PRKAR1A PRKAR1A EFCAB7 EFCAB7 DYNC2H1 DYNC2H1 LOC102748477 LOC102748477 PTRHD1 PTRHD1 CSNK1A1 CSNK1A1 GLI1 GLI1 KIAA0141 KIAA0141 PSMD8 PSMD8 VCP VCP PSME3 PSME3 PSME2 PSME2 PSME1 PSME1 PTCH1 PTCH1 LOC102733981 LOC102733981 PSMB8 PSMB8 PSMC5 PSMC5 SEL1L3 SEL1L3 PRKAR1B PRKAR1B PRKACB PRKACB GLI2 GLI2 LOC102725698 LOC102725698 PSMD14 PSMD14 GPR161 GPR161 PSMC6 PSMC6 PTCHD2 PTCHD2 LOC102747957 LOC102747957 LRP2BP LRP2BP KIF3A KIF3A LOC102729636 LOC102729636 LOC102734657 LOC102734657 DZIP1 DZIP1 PRKAR2A PRKAR2A PSMB2 PSMB2 LOC102750322 LOC102750322 LOC102742178 LOC102742178 RPGRIP1L RPGRIP1L PSMA6 PSMA6 PRKAR2B PRKAR2B PDIA2 PDIA2 PSMC2 PSMC2 LOC102728200 LOC102728200 LOC102738462 LOC102738462 LOC102731945 LOC102731945 SKP1 SKP1 NUMB NUMB CUL1 CUL1 PDCD2L PDCD2L PSMB10 PSMB10 RBX1 RBX1 ADCY6 ADCY6 DHH DHH PSMB4 PSMB4 CDC73 CDC73 PSMD4 PSMD4 SPOPL SPOPL INTU INTU
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SYVN1E3 ubiquitin-protein ligase synoviolin. (612 aa)
LOC10273085126S protease regulatory subunit 6A-like. (200 aa)
LOC102746862ubiquitin-40S ribosomal protein S27a-like isoform X1. (156 aa)
LOC102741471Parafibromin-like. (141 aa)
LOC102735156Proteasome subunit beta type-5-like. (119 aa)
LOC102731038Adenylate cyclase type 9-like; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (564 aa)
LOC102732367Proteasome subunit beta type-1-like. (140 aa)
SHHSonic hedgehog protein-like. (286 aa)
LOC10272921926S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (778 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa)
PSMD626S proteasome non-ATPase regulatory subunit 6 isoform X1. (389 aa)
NUMBLNumb-like protein-like. (413 aa)
LOC10272638126S proteasome non-ATPase regulatory subunit 1-like. (574 aa)
GSK3AGlycogen synthase kinase-3 alpha; Belongs to the protein kinase superfamily. (419 aa)
LOC102744495Zinc finger protein GLI2-like. (460 aa)
LOC102734751Intraflagellar transport protein 172 homolog. (1210 aa)
PSMA5Proteasome subunit alpha type. (235 aa)
PSMD1026S proteasome non-ATPase regulatory subunit 10 isoform X1. (226 aa)
MKS1Meckel syndrome type 1 protein. (262 aa)
LOC102750402E3 ubiquitin-protein ligase SMURF1-like. (321 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
LOC10273512726S protease regulatory subunit 4-like isoform X1; Belongs to the AAA ATPase family. (440 aa)
LOC102747337ubiquitin-40S ribosomal protein S27a-like. (154 aa)
HHATLProtein-cysteine N-palmitoyltransferase HHAT-like protein; Belongs to the membrane-bound acyltransferase family. (504 aa)
IFT57Intraflagellar transport protein 57 homolog. (429 aa)
UBA52ubiquitin-60S ribosomal protein L40 isoform X3. (128 aa)
KXD1kxDL motif-containing protein 1 isoform X1. (176 aa)
ULK3Serine/threonine-protein kinase ULK3 isoform X1. (382 aa)
SPOPSpeckle-type POZ protein isoform X1. (374 aa)
PSMD926S proteasome non-ATPase regulatory subunit 9 isoform X1. (223 aa)
PSMB11Proteasome subunit beta. (285 aa)
PSMB5Proteasome subunit beta type-5. (160 aa)
PSMF1Proteasome inhibitor PI31 subunit. (128 aa)
LOC102746012Adenylate cyclase type 3-like; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (311 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
LOC102751154Numb-like protein-like. (141 aa)
LOC102736400Ellis-van Creveld syndrome protein-like. (192 aa)
THAP7THAP domain-containing protein 7. (313 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
ADCY9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (790 aa)
PSMD1126S proteasome non-ATPase regulatory subunit 11. (422 aa)
FUZProtein fuzzy homolog isoform X1. (418 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
HHIPHedgehog-interacting protein-like. (662 aa)
ADRBK1G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (647 aa)
LOC102749886Intraflagellar transport protein 172 homolog. (168 aa)
PSMB6Proteasome subunit beta. (239 aa)
P4HBProtein disulfide-isomerase. (510 aa)
LOC102735500Cyclic nucleotide-binding domain-containing protein 2-like. (147 aa)
PSMD726S proteasome non-ATPase regulatory subunit 7-like. (324 aa)
DISP2Protein dispatched homolog 2. (686 aa)
TUBTubby-like protein; Belongs to the TUB family. (507 aa)
GSK3BGlycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa)
LOC102739114Intraflagellar transport protein 140 homolog. (375 aa)
PRKAR1AcAMP-dependent protein kinase type I-alpha regulatory subunit. (381 aa)
EFCAB7EF-hand calcium-binding domain-containing protein 7 isoform X1. (629 aa)
DYNC2H1Cytoplasmic dynein 2 heavy chain 1. (386 aa)
LOC102748477Spermatogenesis-associated protein 5-like; Belongs to the AAA ATPase family. (137 aa)
PTRHD1Putative peptidyl-tRNA hydrolase PTRHD1. (140 aa)
CSNK1A1Casein kinase I isoform alpha; Belongs to the protein kinase superfamily. (227 aa)
GLI1Zinc finger protein GLI1 isoform X1. (1105 aa)
KIAA0141Death ligand signal enhancer. (522 aa)
PSMD8LOW QUALITY PROTEIN: 26S proteasome non-ATPase regulatory subunit 8. (351 aa)
VCPTransitional endoplasmic reticulum ATPase isoform X1; Belongs to the AAA ATPase family. (806 aa)
PSME3Proteasome activator complex subunit 3 isoform X3. (254 aa)
PSME2Proteasome activator complex subunit 2 isoform X1. (239 aa)
PSME1Proteasome activator complex subunit 1 isoform X1. (249 aa)
PTCH1Protein patched homolog 1. (1301 aa)
LOC10273398126S proteasome non-ATPase regulatory subunit 2-like. (125 aa)
PSMB8Proteasome subunit beta. (276 aa)
PSMC526S protease regulatory subunit 8; Belongs to the AAA ATPase family. (406 aa)
SEL1L3Protein sel-1 homolog 3-like. (338 aa)
PRKAR1BcAMP-dependent protein kinase type I-beta regulatory subunit. (145 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa)
GLI2Zinc finger protein GLI2. (556 aa)
LOC102725698Zinc finger protein GLI2-like. (368 aa)
PSMD1426S proteasome non-ATPase regulatory subunit 14. (310 aa)
GPR161G-protein coupled receptor 161 isoform X2. (398 aa)
PSMC626S protease regulatory subunit 10B. (291 aa)
PTCHD2Patched domain-containing protein 2. (1393 aa)
LOC102747957Meckel syndrome type 1 protein-like. (318 aa)
LRP2BPLRP2-binding protein. (348 aa)
KIF3AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (726 aa)
LOC102729636polyubiquitin-B-like. (77 aa)
LOC10273465726S proteasome non-ATPase regulatory subunit 1-like. (279 aa)
DZIP1Zinc finger protein DZIP1. (789 aa)
PRKAR2AcAMP-dependent protein kinase type II-alpha regulatory subunit. (391 aa)
PSMB2Proteasome subunit beta. (201 aa)
LOC102750322polyubiquitin-B-like. (153 aa)
LOC102742178Proteasome subunit alpha type. (234 aa)
RPGRIP1LProtein fantom isoform X2. (1244 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
PRKAR2BcAMP-dependent protein kinase type II-beta regulatory subunit. (417 aa)
PDIA2Protein disulfide-isomerase A2. (524 aa)
PSMC226S protease regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa)
LOC102728200ubiquitin-40S ribosomal protein S27a-like. (154 aa)
LOC102738462Cell adhesion molecule-related/down-regulated by oncogenes-like. (620 aa)
LOC102731945Suppressor of fused homolog. (106 aa)
SKP1S-phase kinase-associated protein 1 isoform X1; Belongs to the SKP1 family. (163 aa)
NUMBProtein numb homolog isoform X1. (653 aa)
CUL1Cullin-1; Belongs to the cullin family. (327 aa)
PDCD2LProgrammed cell death protein 2-like. (366 aa)
PSMB10Proteasome subunit beta. (273 aa)
RBX1E3 ubiquitin-protein ligase RBX1 isoform X3. (108 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1161 aa)
DHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (396 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
CDC73Parafibromin. (418 aa)
PSMD426S proteasome non-ATPase regulatory subunit 4. (377 aa)
SPOPLSpeckle-type POZ protein-like isoform X1. (392 aa)
INTUProtein inturned. (943 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.