(18 nodes) Translesion synthesis by POLK network (Leptonychotes weddellii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RPA4	LOW QUALITY PROTEIN: replication protein A4, 30kDa. (262 aa)
	RFC3	Replication factor C subunit 3. (356 aa)
	LOC102728200	ubiquitin-40S ribosomal protein S27a-like. (154 aa)
	LOC102750322	polyubiquitin-B-like. (153 aa)
	LOC102729636	polyubiquitin-B-like. (77 aa)
	REV3L	DNA polymerase zeta catalytic subunit. (3024 aa)
	PCNA	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
	KXD1	kxDL motif-containing protein 1 isoform X1. (176 aa)
	RFC2	Replication factor C subunit 2 isoform X1. (368 aa)
	RFC4	Replication factor C subunit 4. (363 aa)
	LOC102746412	Replication protein A 32 kDa subunit-like. (124 aa)
	UBA52	ubiquitin-60S ribosomal protein L40 isoform X3. (128 aa)
	LOC102747337	ubiquitin-40S ribosomal protein S27a-like. (154 aa)
	RFC5	Replication factor C subunit 5 isoform X1. (340 aa)
	LOC102746862	ubiquitin-40S ribosomal protein S27a-like isoform X1. (156 aa)
	RPA3	Replication protein A 14 kDa subunit. (121 aa)
	RCBTB1	RCC1 and BTB domain-containing protein 1. (531 aa)
	MEIOB	Meiosis-specific with OB domain-containing protein. (300 aa)

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KXD1	LOC102728200	A0A2U3YUL4	A0A2U3XJ47	kxDL motif-containing protein 1 isoform X1.	ubiquitin-40S ribosomal protein S27a-like.	0.884
KXD1	LOC102729636	A0A2U3YUL4	A0A2U3XSD5	kxDL motif-containing protein 1 isoform X1.	polyubiquitin-B-like.	0.866
KXD1	LOC102746862	A0A2U3YUL4	A0A2U3Z815	kxDL motif-containing protein 1 isoform X1.	ubiquitin-40S ribosomal protein S27a-like isoform X1.	0.887
KXD1	LOC102747337	A0A2U3YUL4	A0A2U3YWH0	kxDL motif-containing protein 1 isoform X1.	ubiquitin-40S ribosomal protein S27a-like.	0.552
KXD1	LOC102750322	A0A2U3YUL4	A0A2U3XMJ2	kxDL motif-containing protein 1 isoform X1.	polyubiquitin-B-like.	0.771
KXD1	UBA52	A0A2U3YUL4	A0A2U3YV30	kxDL motif-containing protein 1 isoform X1.	ubiquitin-60S ribosomal protein L40 isoform X3.	0.899
LOC102728200	KXD1	A0A2U3XJ47	A0A2U3YUL4	ubiquitin-40S ribosomal protein S27a-like.	kxDL motif-containing protein 1 isoform X1.	0.884
LOC102728200	LOC102729636	A0A2U3XJ47	A0A2U3XSD5	ubiquitin-40S ribosomal protein S27a-like.	polyubiquitin-B-like.	0.789
LOC102728200	LOC102746412	A0A2U3XJ47	A0A2U3YHP5	ubiquitin-40S ribosomal protein S27a-like.	Replication protein A 32 kDa subunit-like.	0.400
LOC102728200	LOC102750322	A0A2U3XJ47	A0A2U3XMJ2	ubiquitin-40S ribosomal protein S27a-like.	polyubiquitin-B-like.	0.999
LOC102728200	MEIOB	A0A2U3XJ47	A0A2U3YE20	ubiquitin-40S ribosomal protein S27a-like.	Meiosis-specific with OB domain-containing protein.	0.461
LOC102728200	PCNA	A0A2U3XJ47	A0A2U3XVX8	ubiquitin-40S ribosomal protein S27a-like.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.847
LOC102728200	RFC2	A0A2U3XJ47	A0A2U3YR32	ubiquitin-40S ribosomal protein S27a-like.	Replication factor C subunit 2 isoform X1.	0.511
LOC102728200	RFC3	A0A2U3XJ47	A0A2U3XC21	ubiquitin-40S ribosomal protein S27a-like.	Replication factor C subunit 3.	0.511
LOC102728200	RFC4	A0A2U3XJ47	A0A2U3YHT9	ubiquitin-40S ribosomal protein S27a-like.	Replication factor C subunit 4.	0.511
LOC102728200	RFC5	A0A2U3XJ47	A0A2U3Z142	ubiquitin-40S ribosomal protein S27a-like.	Replication factor C subunit 5 isoform X1.	0.511
LOC102728200	RPA3	A0A2U3XJ47	A0A2U3XYM8	ubiquitin-40S ribosomal protein S27a-like.	Replication protein A 14 kDa subunit.	0.531
LOC102728200	RPA4	A0A2U3XJ47	A0A2U3Z926	ubiquitin-40S ribosomal protein S27a-like.	LOW QUALITY PROTEIN: replication protein A4, 30kDa.	0.400
LOC102728200	UBA52	A0A2U3XJ47	A0A2U3YV30	ubiquitin-40S ribosomal protein S27a-like.	ubiquitin-60S ribosomal protein L40 isoform X3.	0.999
LOC102729636	KXD1	A0A2U3XSD5	A0A2U3YUL4	polyubiquitin-B-like.	kxDL motif-containing protein 1 isoform X1.	0.866